SMT201300034B - Genetica inversa che utilizza promotori pol i non-endogeni - Google Patents

Genetica inversa che utilizza promotori pol i non-endogeni

Info

Publication number
SMT201300034B
SMT201300034B SM201300034T SM201300034T SMT201300034B SM T201300034 B SMT201300034 B SM T201300034B SM 201300034 T SM201300034 T SM 201300034T SM 201300034 T SM201300034 T SM 201300034T SM T201300034 B SMT201300034 B SM T201300034B
Authority
SM
San Marino
Prior art keywords
polis
promoters
endogenous
reverse genetics
genetics
Prior art date
Application number
SM201300034T
Other languages
English (en)
Inventor
Philip Dormitzer
Pirada Suphaphiphat
Bjoern Keiner
Michael Franti
Peter Mason
Stephania Crotta
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SMT201300034B publication Critical patent/SMT201300034B/it

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • C12N2760/16011Orthomyxoviridae
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    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16041Use of virus, viral particle or viral elements as a vector
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    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16051Methods of production or purification of viral material
    • C12N2760/16052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16211Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2830/00Vector systems having a special element relevant for transcription
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Mushroom Cultivation (AREA)
  • Data Exchanges In Wide-Area Networks (AREA)
SM201300034T 2009-05-21 2013-03-27 Genetica inversa che utilizza promotori pol i non-endogeni SMT201300034B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21691909P 2009-05-21 2009-05-21
PCT/IB2010/001332 WO2010133964A1 (en) 2009-05-21 2010-05-21 Reverse genetics using non-endogenous pol i promoters

Publications (1)

Publication Number Publication Date
SMT201300034B true SMT201300034B (it) 2013-05-06

Family

ID=42338045

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201300034T SMT201300034B (it) 2009-05-21 2013-03-27 Genetica inversa che utilizza promotori pol i non-endogeni

Country Status (19)

Country Link
US (3) US9072702B2 (it)
EP (2) EP2573184A1 (it)
JP (2) JP5836266B2 (it)
KR (1) KR101800245B1 (it)
CN (1) CN102597246B (it)
AU (1) AU2010250832B2 (it)
BR (1) BRPI1011171A2 (it)
CA (1) CA2762802A1 (it)
DK (1) DK2401384T3 (it)
EA (1) EA021009B1 (it)
ES (1) ES2394797T3 (it)
HK (1) HK1165827A1 (it)
HR (1) HRP20121048T1 (it)
NZ (1) NZ596432A (it)
PL (1) PL2401384T3 (it)
PT (1) PT2401384E (it)
SI (1) SI2401384T1 (it)
SM (1) SMT201300034B (it)
WO (1) WO2010133964A1 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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US7985401B2 (en) 2003-10-31 2011-07-26 The Regents Of The University Of California Peptides whose uptake by cells is controllable
KR101800245B1 (ko) * 2009-05-21 2017-11-22 노파르티스 아게 비-내인성 pol i 프로모터를 사용하는 역 유전학
KR101323582B1 (ko) * 2011-03-17 2013-10-30 충북대학교 산학협력단 Vero 세포 유래의 polⅠ 프로모터 및 이를 포함하는 재조합 벡터
AU2013354219A1 (en) 2012-12-03 2015-07-02 Novartis Ag Reassortant influenza a viren
AU2014229255B2 (en) 2013-03-13 2018-12-13 Novartis Ag Influenza B virus reassortment
CA2914604A1 (en) 2013-06-06 2014-12-11 Novartis Ag Influenza virus reassortment
WO2016148195A1 (ja) * 2015-03-17 2016-09-22 一般財団法人阪大微生物病研究会 インフルエンザウイルス作出用細胞
MX2018015540A (es) * 2016-06-20 2019-04-11 Janssen Vaccines & Prevention Bv Promotor bidireccional potente y equilibrado.
JP2023502650A (ja) 2019-11-18 2023-01-25 セキラス ピーティーワイ リミテッド 遺伝子再集合インフルエンザウイルスを産生するための方法
BR102020010208A2 (pt) 2020-05-21 2022-04-12 Fundação Oswaldo Cruz Construção de ácido nucleico, virus influenza recombinante, método para preparar um virus influenza recombinante, composição, e, uso.

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Also Published As

Publication number Publication date
US20160024525A1 (en) 2016-01-28
ES2394797T3 (es) 2013-02-05
HRP20121048T1 (hr) 2013-02-28
AU2010250832B2 (en) 2013-10-03
EP2401384B1 (en) 2012-10-03
HK1165827A1 (en) 2012-10-12
JP5836266B2 (ja) 2015-12-24
US9072702B2 (en) 2015-07-07
JP2015204843A (ja) 2015-11-19
KR101800245B1 (ko) 2017-11-22
KR20120028328A (ko) 2012-03-22
CN102597246B (zh) 2014-02-26
EA201171449A1 (ru) 2012-05-30
NZ596432A (en) 2013-05-31
EP2573184A1 (en) 2013-03-27
BRPI1011171A2 (pt) 2015-08-25
PL2401384T3 (pl) 2013-03-29
DK2401384T3 (da) 2013-01-14
WO2010133964A1 (en) 2010-11-25
CN102597246A (zh) 2012-07-18
US20120189656A1 (en) 2012-07-26
CA2762802A1 (en) 2010-11-25
AU2010250832A1 (en) 2011-12-08
PT2401384E (pt) 2012-12-19
SI2401384T1 (sl) 2013-01-31
JP2012527228A (ja) 2012-11-08
EA021009B1 (ru) 2015-03-31
EP2401384A1 (en) 2012-01-04
US20190284575A1 (en) 2019-09-19

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