EA201101014A1 - Сульфонамиды, предназначенные для лечения респираторных нарушений - Google Patents

Сульфонамиды, предназначенные для лечения респираторных нарушений

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Publication number
EA201101014A1
EA201101014A1 EA201101014A EA201101014A EA201101014A1 EA 201101014 A1 EA201101014 A1 EA 201101014A1 EA 201101014 A EA201101014 A EA 201101014A EA 201101014 A EA201101014 A EA 201101014A EA 201101014 A1 EA201101014 A1 EA 201101014A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
sulphonamides
intended
respiratory disorders
alkyl
Prior art date
Application number
EA201101014A
Other languages
English (en)
Other versions
EA019441B1 (ru
Inventor
Видя Рамдас
Харри Финч
Крейг Фокс
Original Assignee
Палмаджен Терепьютикс (Инфлеммейшн) Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Палмаджен Терепьютикс (Инфлеммейшн) Лимитед filed Critical Палмаджен Терепьютикс (Инфлеммейшн) Лимитед
Publication of EA201101014A1 publication Critical patent/EA201101014A1/ru
Publication of EA019441B1 publication Critical patent/EA019441B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

В заявке описаны соединения формулы (I), которые являются агонистами PPARγ, применимые для лечения респираторного заболеванияв которой R, Rили R, все, независимо обозначают галоген, цианогруппу, нитрогруппу, аминогруппу, алкил, галогеналкил, алкоксигруппу, галогеналкоксигруппу, карбоновую кислоту или ее эфир или амид; Rобозначает водород или алкил; m, n или р независимо равны 0, 1, 2 или 3.
EA201101014A 2008-12-30 2009-12-23 Сульфонамиды, предназначенные для лечения респираторных нарушений EA019441B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN3324CH2008 2008-12-30
PCT/GB2009/002951 WO2010076553A1 (en) 2008-12-30 2009-12-23 Sulfonamide compounds for the treatment of respiratory disorders

Publications (2)

Publication Number Publication Date
EA201101014A1 true EA201101014A1 (ru) 2012-01-30
EA019441B1 EA019441B1 (ru) 2014-03-31

Family

ID=41600475

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201101014A EA019441B1 (ru) 2008-12-30 2009-12-23 Сульфонамиды, предназначенные для лечения респираторных нарушений

Country Status (22)

Country Link
US (1) US8362064B2 (ru)
EP (1) EP2379507B1 (ru)
JP (1) JP5555255B2 (ru)
CN (1) CN102272104B (ru)
AU (1) AU2009334597B2 (ru)
BR (1) BRPI0923862A2 (ru)
CA (1) CA2748331C (ru)
CY (1) CY1114798T1 (ru)
DK (1) DK2379507T3 (ru)
EA (1) EA019441B1 (ru)
ES (1) ES2442343T3 (ru)
HK (1) HK1158626A1 (ru)
HR (1) HRP20140022T1 (ru)
MX (1) MX2011007036A (ru)
NZ (1) NZ594157A (ru)
PL (1) PL2379507T3 (ru)
PT (1) PT2379507E (ru)
SG (1) SG172444A1 (ru)
SI (1) SI2379507T1 (ru)
SM (1) SMT201300156B (ru)
WO (1) WO2010076553A1 (ru)
ZA (1) ZA201104663B (ru)

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Also Published As

Publication number Publication date
BRPI0923862A2 (pt) 2015-07-28
NZ594157A (en) 2013-07-26
DK2379507T3 (da) 2014-01-27
EA019441B1 (ru) 2014-03-31
MX2011007036A (es) 2011-07-20
JP2012514027A (ja) 2012-06-21
WO2010076553A1 (en) 2010-07-08
CN102272104B (zh) 2014-07-09
EP2379507B1 (en) 2013-10-16
CY1114798T1 (el) 2016-12-14
HK1158626A1 (en) 2012-07-20
CA2748331C (en) 2016-08-02
ES2442343T3 (es) 2014-02-11
ZA201104663B (en) 2012-10-31
PT2379507E (pt) 2014-01-21
US8362064B2 (en) 2013-01-29
JP5555255B2 (ja) 2014-07-23
US20120041043A1 (en) 2012-02-16
EP2379507A1 (en) 2011-10-26
HRP20140022T1 (hr) 2014-02-14
AU2009334597A1 (en) 2011-07-21
CA2748331A1 (en) 2010-07-08
CN102272104A (zh) 2011-12-07
SMT201300156B (it) 2014-03-07
SI2379507T1 (sl) 2014-02-28
PL2379507T3 (pl) 2014-03-31
AU2009334597B2 (en) 2015-07-16
SG172444A1 (en) 2011-07-28

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