EA201071100A1 - Пиридилсодержащие ингибиторы передачи сигнала через белок hedgehog - Google Patents

Пиридилсодержащие ингибиторы передачи сигнала через белок hedgehog

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Publication number
EA201071100A1
EA201071100A1 EA201071100A EA201071100A EA201071100A1 EA 201071100 A1 EA201071100 A1 EA 201071100A1 EA 201071100 A EA201071100 A EA 201071100A EA 201071100 A EA201071100 A EA 201071100A EA 201071100 A1 EA201071100 A1 EA 201071100A1
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EA
Eurasian Patent Office
Prior art keywords
signal transmission
inhibitors
hedgehog
pyridyl
containing signal
Prior art date
Application number
EA201071100A
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English (en)
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EA020192B1 (ru
Inventor
Джанет Л. Гунцнер
Даниэл П. Сатерлин
Марк С. Стэнли
Лян Бао
Джорджетт Кастанедо
Ребекка Л. Лалонд
Шумэй Ван
Марк И. Рейнолдс
Скотт Дж. Сэвидж
Кимберли Малески
Майкл С. Дайна
Original Assignee
Дженентек, Инк.
Кьюрис, Инк.
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Family has litigation
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Application filed by Дженентек, Инк., Кьюрис, Инк. filed Critical Дженентек, Инк.
Publication of EA201071100A1 publication Critical patent/EA201071100A1/ru
Publication of EA020192B1 publication Critical patent/EA020192B1/ru

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Abstract

Согласно настоящему изобретению предложены новые ингибиторы передачи сигнала с участием белка hedgehog, которые можно применять в качестве терапевтического агента для лечения злокачественных новообразований, причем указанные соединения имеют общую формулу (I)где А, X, Y, R, R, R, R, m и n определены в настоящем описании.
EA201071100A 2008-04-11 2009-04-10 Пиридилсодержащие ингибиторы передачи сигнала через белок hedgehog EA020192B1 (ru)

Applications Claiming Priority (2)

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