EA201001755A1 - Новые соединения азабицикло[3.2.0]гепт-3-ила, способ их получения и фармацевтические композиции, которые их содержат - Google Patents

Новые соединения азабицикло[3.2.0]гепт-3-ила, способ их получения и фармацевтические композиции, которые их содержат

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Publication number
EA201001755A1
EA201001755A1 EA201001755A EA201001755A EA201001755A1 EA 201001755 A1 EA201001755 A1 EA 201001755A1 EA 201001755 A EA201001755 A EA 201001755A EA 201001755 A EA201001755 A EA 201001755A EA 201001755 A1 EA201001755 A1 EA 201001755A1
Authority
EA
Eurasian Patent Office
Prior art keywords
ila
azabicyclo
hept
contain
production
Prior art date
Application number
EA201001755A
Other languages
English (en)
Other versions
EA018971B1 (ru
Inventor
Патрик Касара
Анне-Мари Шолле
Ален Дено
Пьер Лестаж
Фани Панайи
Original Assignee
Ле Лаборатуар Сервье
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ле Лаборатуар Сервье filed Critical Ле Лаборатуар Сервье
Publication of EA201001755A1 publication Critical patent/EA201001755A1/ru
Publication of EA018971B1 publication Critical patent/EA018971B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)

Abstract

Соединения формулы (I)где ALK представляет собой алкиленовую цепь, W представляет собой группугде R и R' имеют значения, указанные в описании. Лекарственное средство.
EA201001755A 2009-12-09 2010-12-07 Соединения азабицикло[3.2.0]гепт-3-ила, способ их получения и фармацевтические композиции, которые их содержат EA018971B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0905957A FR2953514B1 (fr) 2009-12-09 2009-12-09 Nouveaux derives azabicyclo[3.2.0]hept-3-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
EA201001755A1 true EA201001755A1 (ru) 2011-10-31
EA018971B1 EA018971B1 (ru) 2013-12-30

Family

ID=42133738

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001755A EA018971B1 (ru) 2009-12-09 2010-12-07 Соединения азабицикло[3.2.0]гепт-3-ила, способ их получения и фармацевтические композиции, которые их содержат

Country Status (44)

Country Link
US (1) US8008337B2 (ru)
EP (1) EP2332910B1 (ru)
JP (1) JP5511645B2 (ru)
KR (1) KR101292705B1 (ru)
CN (1) CN102127004B (ru)
AP (1) AP2755A (ru)
AR (1) AR079268A1 (ru)
AU (1) AU2010246426B2 (ru)
BR (1) BRPI1005270A2 (ru)
CA (1) CA2724151C (ru)
CL (1) CL2010001309A1 (ru)
CO (1) CO6280059A1 (ru)
CR (1) CR11811A (ru)
CU (1) CU23993B1 (ru)
CY (1) CY1113971T1 (ru)
DK (1) DK2332910T3 (ru)
EA (1) EA018971B1 (ru)
EC (1) ECSP10010649A (ru)
ES (1) ES2405206T3 (ru)
FR (1) FR2953514B1 (ru)
GE (1) GEP20135801B (ru)
HN (1) HN2010002593A (ru)
HR (1) HRP20130307T1 (ru)
IL (1) IL209463A (ru)
JO (1) JO2880B1 (ru)
MA (1) MA32444B1 (ru)
ME (1) ME01504B (ru)
MX (1) MX2010013093A (ru)
MY (1) MY150598A (ru)
NI (1) NI201000206A (ru)
NZ (1) NZ589763A (ru)
PE (1) PE20110542A1 (ru)
PL (1) PL2332910T3 (ru)
PT (1) PT2332910E (ru)
RS (1) RS52698B (ru)
SA (1) SA110320007B1 (ru)
SG (1) SG172543A1 (ru)
SI (1) SI2332910T1 (ru)
SV (1) SV2010003746A (ru)
TW (1) TWI419875B (ru)
UA (1) UA106721C2 (ru)
UY (1) UY33046A (ru)
WO (1) WO2011070250A1 (ru)
ZA (1) ZA201008651B (ru)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9300625B (sl) * 1993-12-02 2002-02-28 Basf Aktiengesellschaft N-substituirani derivati azabicikloheptana, njihova priprava in uporaba
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4427647A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
SV2010003746A (es) 2011-03-15
IL209463A (en) 2014-06-30
AR079268A1 (es) 2012-01-04
HRP20130307T1 (hr) 2013-04-30
ME01504B (me) 2014-04-20
EP2332910A1 (fr) 2011-06-15
MX2010013093A (es) 2011-06-14
SI2332910T1 (sl) 2013-05-31
CA2724151A1 (fr) 2011-06-09
CR11811A (es) 2011-02-04
AP2755A (en) 2013-09-30
EA018971B1 (ru) 2013-12-30
CU20100236A7 (es) 2011-11-15
JO2880B1 (en) 2015-03-15
MA32444B1 (fr) 2011-07-03
JP5511645B2 (ja) 2014-06-04
KR20110065384A (ko) 2011-06-15
US8008337B2 (en) 2011-08-30
UA106721C2 (ru) 2014-10-10
ZA201008651B (en) 2011-10-26
FR2953514B1 (fr) 2011-12-23
NZ589763A (en) 2012-05-25
TW201200498A (en) 2012-01-01
NI201000206A (es) 2014-01-07
CN102127004B (zh) 2013-10-23
US20110136886A1 (en) 2011-06-09
ES2405206T3 (es) 2013-05-30
GEP20135801B (en) 2013-04-10
PT2332910E (pt) 2013-02-26
CA2724151C (fr) 2013-03-26
AP2010005489A0 (en) 2010-12-31
BRPI1005270A2 (pt) 2013-04-30
MY150598A (en) 2014-01-30
HN2010002593A (es) 2013-03-18
ECSP10010649A (es) 2011-07-29
AU2010246426B2 (en) 2013-06-27
CL2010001309A1 (es) 2012-01-13
PE20110542A1 (es) 2011-08-18
RS52698B (en) 2013-08-30
CO6280059A1 (es) 2011-05-20
JP2011121945A (ja) 2011-06-23
CY1113971T1 (el) 2016-07-27
PL2332910T3 (pl) 2013-06-28
FR2953514A1 (fr) 2011-06-10
CN102127004A (zh) 2011-07-20
AU2010246426A1 (en) 2011-06-23
CU23993B1 (es) 2014-04-24
EP2332910B1 (fr) 2013-01-30
DK2332910T3 (da) 2013-05-13
IL209463A0 (en) 2011-02-28
SG172543A1 (en) 2011-07-28
WO2011070250A1 (fr) 2011-06-16
SA110320007B1 (ar) 2013-10-03
UY33046A (es) 2011-05-31
KR101292705B1 (ko) 2013-08-02
TWI419875B (zh) 2013-12-21

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU