EA200700395A1 - Спектрометр подвижности ионов - Google Patents

Спектрометр подвижности ионов

Info

Publication number
EA200700395A1
EA200700395A1 EA200700395A EA200700395A EA200700395A1 EA 200700395 A1 EA200700395 A1 EA 200700395A1 EA 200700395 A EA200700395 A EA 200700395A EA 200700395 A EA200700395 A EA 200700395A EA 200700395 A1 EA200700395 A1 EA 200700395A1
Authority
EA
Eurasian Patent Office
Prior art keywords
spectrometer
ion
electrodes
ion mobility
description
Prior art date
Application number
EA200700395A
Other languages
English (en)
Inventor
Пол Бойл
Эндрю Кель
Дэвид Руис Алонсо
Original Assignee
Оулстоун Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0417184A external-priority patent/GB0417184D0/en
Priority claimed from GB0500812A external-priority patent/GB0500812D0/en
Application filed by Оулстоун Лтд. filed Critical Оулстоун Лтд.
Publication of EA200700395A1 publication Critical patent/EA200700395A1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

Предлагается описание спектрометра подвижности ионов, содержащего ионный фильтр в виде по меньшей мере одного ионного канала, содержащего множество электродов. Изменяющийся во времени электрический потенциал, подаваемый на проводящие слои, позволяет фильтру селективно пропускать некоторые виды ионов. Электрический потенциал содержит движущую и поперечную компоненты, и в предпочтительных вариантах осуществления каждый из электродов участвует в создании компоненты как движущего, так и поперечного полей. Устройство можно применять без дрейфового газового потока. Предложено описание технологий микрообработки для изготовления микромасштабных спектрометров, а также разнообразные применения спектрометра.
EA200700395A 2004-08-02 2005-08-02 Спектрометр подвижности ионов EA200700395A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0417184A GB0417184D0 (en) 2004-08-02 2004-08-02 Microchip ion mobility spectrometer
GB0500812A GB0500812D0 (en) 2005-01-17 2005-01-17 Ion mobility spectrometer
PCT/GB2005/050124 WO2006013396A2 (en) 2004-08-02 2005-08-02 Ion mobility spectrometer

Publications (1)

Publication Number Publication Date
EA200700395A1 true EA200700395A1 (ru) 2008-12-30

Family

ID=35583323

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700395A EA200700395A1 (ru) 2004-08-02 2005-08-02 Спектрометр подвижности ионов

Country Status (14)

Country Link
US (2) US7714278B2 (ru)
EP (1) EP1779409A2 (ru)
JP (1) JP5221954B2 (ru)
KR (1) KR20070052774A (ru)
CN (1) CN101882552A (ru)
AU (1) AU2005268605A1 (ru)
BR (1) BRPI0514095A (ru)
CA (1) CA2575913A1 (ru)
EA (1) EA200700395A1 (ru)
IL (2) IL181140A (ru)
MX (1) MX2007001434A (ru)
NO (1) NO20071168L (ru)
NZ (1) NZ553460A (ru)
WO (1) WO2006013396A2 (ru)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101882552A (zh) * 2004-08-02 2010-11-10 奥斯通有限公司 离子迁移率谱仪
WO2007034239A2 (en) * 2005-09-19 2007-03-29 Owlstone Ltd Ion pump
US20100264304A1 (en) * 2006-04-04 2010-10-21 Martinez-Lozano Pablo Method for detecting volatile species of high molecular weight
CN100587486C (zh) * 2006-05-31 2010-02-03 中国科学院电子学研究所 用于离子迁移率谱仪的微机电表面离化源
GB0618926D0 (en) 2006-09-26 2006-11-08 Owlstone Ltd Ion filter
EP1959476A1 (de) * 2007-02-19 2008-08-20 Technische Universität Hamburg-Harburg Massenspektrometer
US9588081B2 (en) 2007-09-25 2017-03-07 Ownstone Medical Limited Interdigitated electrode configuration for ion filter
US8178045B2 (en) 2007-12-17 2012-05-15 University Of Louisville Research Foundation, Inc. Interchangeable preconcentrator connector assembly
EP2112683A1 (en) 2008-04-22 2009-10-28 IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. Differential mobility spectrometer and operating method therefor
US8627710B2 (en) * 2008-05-05 2014-01-14 Inficon Ab Gas probe for sampling gas molecules from a fluid and a system comprising the gas probe
WO2009157187A1 (ja) 2008-06-23 2009-12-30 Murthy Prakash Sreedhar 化学物質に関連した情報を取り扱うためのシステム
WO2010014950A1 (en) 2008-07-31 2010-02-04 University Of Louisville Rasearch Foundation, Inc. Large volume analyte preconcentrator
US8448532B2 (en) 2009-03-18 2013-05-28 The United States Of America As Represented By The Secretary Of The Navy Actively cooled vapor preconcentrator
US8193488B2 (en) * 2009-06-30 2012-06-05 New Zealand Forest Research Institute Limited Vibrating probe
US8716655B2 (en) * 2009-07-02 2014-05-06 Tricorntech Corporation Integrated ion separation spectrometer
GB0911884D0 (en) * 2009-07-08 2009-08-19 Sideris Dimitrios Mass spectrometer and methods of mass spectrometry
US8569691B2 (en) 2009-11-24 2013-10-29 University Of Louisville Research Foundation Preconcentrator for analysis instruments
EP2518485A4 (en) 2009-12-22 2017-09-06 Atonarp Inc. Device for detecting chemical substances
JPWO2011077732A1 (ja) * 2009-12-22 2013-05-02 アトナープ株式会社 コンテンツを供給する装置
JP5745429B2 (ja) 2009-12-22 2015-07-08 アトナープ株式会社 ロボットおよびロボットを制御する方法
GB2479190B (en) * 2010-04-01 2014-03-19 Microsaic Systems Plc Microengineered multipole rod assembly
GB2479191B (en) * 2010-04-01 2014-03-19 Microsaic Systems Plc Microengineered multipole ion guide
US8812250B2 (en) * 2010-06-18 2014-08-19 Washington State University Ion mobility spectrometry systems and associated methods of operation
JP5815534B2 (ja) 2010-08-31 2015-11-17 アトナープ株式会社 センサーにより測定されたデータから候補を見つける方法および装置
JP5815535B2 (ja) 2010-08-31 2015-11-17 アトナープ株式会社 イオン移動装置
CZ306424B6 (cs) * 2010-10-26 2017-01-18 Vysoké Učení Technické V Brně Filtr iontů pro senzor pro měření extrémně nízkých úrovní koncentrace volných iontů
JP5836967B2 (ja) 2010-10-29 2015-12-24 アトナープ株式会社 分析装置
US8581177B2 (en) * 2011-04-11 2013-11-12 Thermo Finnigan Llc High duty cycle ion storage/ion mobility separation mass spectrometer
DE102011017280A1 (de) 2011-04-15 2012-10-18 Fagus-Grecon Greten Gmbh & Co Kg Verfahren zum Messen von emittierenden flüchtigen Stoffen aus Holzwerkstoffen und Vorrichtung zum Messen von emittierenden flüchtigen Stoffen aus Holzwerkstoffen
US8502138B2 (en) 2011-07-29 2013-08-06 Sharp Kabushiki Kaisha Integrated ion mobility spectrometer
CN103998914B (zh) 2011-09-06 2016-04-06 Atonarp株式会社 气体采集装置以及检查装置
US9285341B2 (en) 2011-09-06 2016-03-15 Atonarp Inc. Apparatus monitoring for abnormalities
JP5453490B2 (ja) 2011-12-21 2014-03-26 財團法人工業技術研究院 除湿と離脱装置及びシステム
US9362099B2 (en) 2012-01-05 2016-06-07 Owlstone Limited Field asymmetric ion mobility spectrometry filter
US9366649B2 (en) * 2012-03-29 2016-06-14 Owlstone Nanotech Inc Field asymmetric ion mobility spectrometry system
US9070542B2 (en) 2012-04-06 2015-06-30 Implant Sciences Corporation Selective ionization using high frequency filtering of reactive ions
WO2013154732A1 (en) * 2012-04-11 2013-10-17 President And Fellows Of Harvard College Buffer gas cooling and mixture analysis
US20150074093A1 (en) 2012-04-25 2015-03-12 Atonarp Inc. System that provides content
US8878127B2 (en) * 2013-03-15 2014-11-04 The University Of North Carolina Of Chapel Hill Miniature charged particle trap with elongated trapping region for mass spectrometry
CN105209898A (zh) 2013-03-18 2015-12-30 蒙特利尔史密斯安检仪公司 具有带电材料输送腔室的离子迁移谱装置
JP6157621B2 (ja) * 2013-07-19 2017-07-05 株式会社日立製作所 イオン移動度分離装置
GB201315145D0 (en) * 2013-08-23 2013-10-09 Smiths Detection Watford Ltd Ion Modification
US20160225597A1 (en) * 2013-09-13 2016-08-04 Inficon Inc. Chemical analyzer with membrane
EP4040147A1 (en) 2014-06-16 2022-08-10 Purdue Research Foundation Sample analysis systems and methods of use thereof
CN104201083A (zh) * 2014-09-04 2014-12-10 同方威视技术股份有限公司 用于离子迁移谱仪的空气干燥器
EP2993177A1 (en) 2014-09-05 2016-03-09 Technische Universität Berlin A chemo-enzymatic preparation method for purine nucleosides and their deaza- and aza- analogues
CN104759189A (zh) * 2015-03-12 2015-07-08 同方威视技术股份有限公司 离子迁移谱仪中可持续工作的气体净化装置
US10209220B2 (en) 2015-11-26 2019-02-19 Korea Basic Science Institute Apparatus for measuring ion mobility of harmful material and reference data obtaining method of the same
DE102015016820A1 (de) * 2015-12-22 2017-06-22 Testo SE & Co. KGaA Partikelmessanordnung
WO2017158534A1 (en) * 2016-03-15 2017-09-21 Dh Technologies Development Pte. Ltd. Systems and methods for multi-channel differential mobility spectrometry
WO2017187141A1 (en) 2016-04-25 2017-11-02 Owlstone Medical Limited A method for collecting a selective portion of a subject's breath
JP6330154B2 (ja) 2016-05-24 2018-05-30 パナソニックＩｐマネジメント株式会社 電界非対称性イオン移動度分光計、およびそれを用いた混合物分離方法
JP6750530B2 (ja) * 2016-08-02 2020-09-02 株式会社リコー イオンフィルタ、イオン検出装置及びイオンフィルタの製造方法
JP7022884B2 (ja) * 2017-03-31 2022-02-21 パナソニックＩｐマネジメント株式会社 電界非対称性イオン移動度分光計、およびそれを用いた混合物分離方法
JP6937462B2 (ja) * 2017-04-24 2021-09-22 パナソニックＩｐマネジメント株式会社 電界非対称性イオン移動度分光計、およびそれを用いた混合物分離方法
CN107342212B (zh) * 2017-07-18 2019-05-10 上海新示方科技有限公司 一种电离源系统、氢原子频标
CN107342768B (zh) * 2017-07-18 2020-08-11 上海新示方科技有限公司 一种氢原子频标
GB2566326A (en) * 2017-09-11 2019-03-13 Owlstone Inc Ion mobility filter
GB2573483B (en) * 2017-10-06 2022-05-11 Owlstone Inc Ion Mobility Filter
GB2568480A (en) * 2017-11-16 2019-05-22 Owlstone Inc Method of manufacture for a ion mobility filter
JP7102733B2 (ja) 2018-01-04 2022-07-20 株式会社リコー イオン検出装置及び電界非対称波形イオン移動度分光分析システム
JP7069742B2 (ja) * 2018-01-23 2022-05-18 株式会社リコー イオンフィルタ、イオン検出装置及びイオンフィルタの製造方法
US11874251B2 (en) 2018-02-13 2024-01-16 Jp Scientific Limited Ion mobility spectrometer and method of analyzing ions
EP3752822A4 (en) * 2018-02-13 2021-11-24 JP Scientific Limited ION MOBILITY SPECTROMETERS AND METHOD OF ANALYSIS OF IONS
CN112840434A (zh) 2018-05-14 2021-05-25 莫比莱昂系统有限公司 离子迁移率谱仪与质谱仪的耦合
GB2582367B (en) 2019-03-21 2021-03-24 Owlstone Med Ltd Method of manufacture for an ion mobility filter
EP3972726A4 (en) 2019-05-21 2023-05-10 Mobilion Systems, Inc. VOLTAGE CONTROL FOR ION MOBILITY SEPARATION
US11543384B2 (en) 2019-11-22 2023-01-03 MOBILion Systems, Inc. Mobility based filtering of ions
JP7276751B2 (ja) * 2020-03-05 2023-05-18 新東工業株式会社 ガス測定器及びガス測定方法
WO2021207235A1 (en) 2020-04-06 2021-10-14 MOBILion Systems, Inc. Systems and methods for two-dimensional mobility based filtering of ions
EP4153985A4 (en) 2020-05-22 2024-07-10 Mobilion Systems Inc METHODS AND APPARATUS FOR ION TRAPPING AND ACCUMULATION
US11874252B2 (en) 2020-06-05 2024-01-16 MOBILion Systems, Inc. Apparatus and methods for ion manipulation having improved duty cycle
KR102218535B1 (ko) 2020-08-24 2021-02-22 주식회사 이온랩토리 이온 이동도 분광장치 및 이를 활용한 대기 분석시스템
CN117665087A (zh) * 2022-08-30 2024-03-08 霍尼韦尔国际公司 采用时分模式在同一物理区执行分离和检测的光电离检测器传感器

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06176734A (ja) * 1991-07-24 1994-06-24 Yukiro Takahashi 電子増倍素子
KR0156602B1 (ko) * 1994-07-08 1998-12-01 황해웅 이온이동도 분석기
GB2291200A (en) * 1994-07-15 1996-01-17 Ion Track Instr Ion mobility spectrometer and method of operation for enhanced detection of narotics
US6051832A (en) * 1996-08-20 2000-04-18 Graseby Dynamics Limited Drift chambers
DE19730898C2 (de) 1997-07-18 1999-06-17 Bruker Saxonia Analytik Gmbh Verfahren zum Erstellen eines Ionenmobilitätsspektrums
US5789745A (en) 1997-10-28 1998-08-04 Sandia Corporation Ion mobility spectrometer using frequency-domain separation
US6512224B1 (en) * 1999-07-21 2003-01-28 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven field asymmetric ion mobility filter and detection system
US6815668B2 (en) * 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
US6639213B2 (en) * 2000-02-29 2003-10-28 The Texas A & M University System Periodic field focusing ion mobility spectrometer
CA2402628A1 (en) * 2000-03-14 2001-09-20 Roger Guevremont Apparatus and method for trandem icp/faims/ms
JP3758944B2 (ja) * 2000-06-05 2006-03-22 三菱電機株式会社 ガス中イオン量測定装置
US6744043B2 (en) * 2000-12-08 2004-06-01 Mds Inc. Ion mobilty spectrometer incorporating an ion guide in combination with an MS device
US6576899B2 (en) * 2001-01-16 2003-06-10 California Institute Of Technology Direct detection of low-energy charged particles using metal oxide semiconductor circuitry
US6765215B2 (en) * 2001-06-28 2004-07-20 Agilent Technologies, Inc. Super alloy ionization chamber for reactive samples
WO2003038086A1 (en) * 2001-10-31 2003-05-08 Ionfinity Llc Soft ionization device and applications thereof
ES2579804T3 (es) 2003-12-02 2016-08-16 Celavie Biosciences, Llc Composiciones y métodos para la propagación de células progenitoras neurales
CN101882552A (zh) * 2004-08-02 2010-11-10 奥斯通有限公司 离子迁移率谱仪

Also Published As

Publication number Publication date
JP5221954B2 (ja) 2013-06-26
US20110006196A1 (en) 2011-01-13
US8319177B2 (en) 2012-11-27
NO20071168L (no) 2007-04-24
CA2575913A1 (en) 2006-02-09
AU2005268605A1 (en) 2006-02-09
EP1779409A2 (en) 2007-05-02
WO2006013396A2 (en) 2006-02-09
JP2008508693A (ja) 2008-03-21
MX2007001434A (es) 2008-03-07
IL181140A (en) 2011-07-31
IL181140A0 (en) 2007-07-04
WO2006013396A3 (en) 2006-12-21
KR20070052774A (ko) 2007-05-22
US20080191132A1 (en) 2008-08-14
US7714278B2 (en) 2010-05-11
BRPI0514095A (pt) 2008-05-27
NZ553460A (en) 2010-06-25
CN101882552A (zh) 2010-11-10
IL206034A0 (en) 2010-11-30

Similar Documents

Publication Publication Date Title
EA200700395A1 (ru) Спектрометр подвижности ионов
CN105264637B (zh) 离子操作方法和设备
WO2005043115A3 (en) Ion mobility tof/maldi/ms using drift cell alternating high and low electrical field regions
ATE483967T1 (de) Manipulation von analyten mittels elektrischer felder
DE60309725D1 (de) Wellenformgenerator-elektronik mit abgestimmten lc-schaltkreisen
GB2451149B (en) Mass spectrometer
GB201204372D0 (en) Ion mobility separator with variable effective length
GB2455593B (en) Mass spectrometer
WO2006085110A3 (en) Mass spectrometer
CN108701578A (zh) 电离装置的用途、装置及用于电离的气态物质的方法以及用于分析被电离的气态物质的装置和方法
WO2004092705A3 (en) Cross-flow ion mobility analyzer
WO2009118690A3 (en) Microfluidic device and method
Waltman et al. Characterization of a distributed plasma ionization source (DPIS) for ion mobility spectrometry and mass spectrometry
ATE557416T1 (de) Permanentmagnet-ionenfalle und massenspektrometer mit einem solchen magneten
WO2007034239A3 (en) Ion pump
WO2018229724A3 (de) Vorrichtung und verfahren zur ionisation eines analyten sowie vorrichtung und verfahren zur analyse eines ionisierten analyten
EA200500276A1 (ru) Способы и лечение расстройств изменением потока ионов через клеточные мембраны с помощью электрических полей
CN102646571B (zh) 基于离子风抽气系统的高场不对称波形离子迁移谱仪
WO2004077016A3 (en) Ion mobility separation devices
WO2004107389A3 (en) System and method for modifying the fringing fields of a radio frequency multipole
DE60233422D1 (de) Silizium-auf-isolator-hochspannungsbauelementstruktur
RU2013110784A (ru) Способ и устройство для сокращения частиц сажи в отработанном газе двигателя внутреннего сгорания
US7758316B2 (en) Ion micro pump
WO2005081944A3 (en) Ion source with controlled superposition of electrostatic and gas flow fields
CN103311088A (zh) 梳状结构的放电电离源