EA200700329A1 - Биохимический синтез 1,4-бутандиамина - Google Patents

Биохимический синтез 1,4-бутандиамина

Info

Publication number
EA200700329A1
EA200700329A1 EA200700329A EA200700329A EA200700329A1 EA 200700329 A1 EA200700329 A1 EA 200700329A1 EA 200700329 A EA200700329 A EA 200700329A EA 200700329 A EA200700329 A EA 200700329A EA 200700329 A1 EA200700329 A1 EA 200700329A1
Authority
EA
Eurasian Patent Office
Prior art keywords
activity
microorganism
increased
acetylglutamate
formation
Prior art date
Application number
EA200700329A
Other languages
English (en)
Other versions
EA010179B1 (ru
Inventor
Катрин Эппельман
Петрус Мартинус Матеус Носсин
Леон Жан Реньер Мари Равен
Сусанна Мария Кремер
Марсель Герхардус Вубболтс
Original Assignee
ДСМ АйПи АССЕТС Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДСМ АйПи АССЕТС Б.В. filed Critical ДСМ АйПи АССЕТС Б.В.
Publication of EA200700329A1 publication Critical patent/EA200700329A1/ru
Publication of EA010179B1 publication Critical patent/EA010179B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Изобретение относится к способу биохимического синтеза 1,4-бутандиамина в микроорганизме, имеющем повышенный уровень активности ортининдекарбоксилазы (повышенная активность ODC) по сравнению с нативным уровнем орнитиндекарбоксилазы, где у микроорганизма представлена также увеличенная активность образования N-ацетилглутамата по сравнению с исходным уровнем активности образования N-ацетилглутамата в микроорганизме, где производимый в микроорганизме 1,4-бутандиамин секретируется в среду ферментации и выделяется из среды ферментации. Изобретение также относится к векторам, плазмидам и хозяевам, несущим соответствующую увеличенную активность орнитиндекарбоксилазы и увеличенную активность образования N-ацетилглутамата.
EA200700329A 2004-07-15 2005-07-11 Биохимический синтез 1,4-бутандиамина EA010179B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04077046 2004-07-15
PCT/EP2005/007606 WO2006005603A1 (en) 2004-07-15 2005-07-11 Biochemical synthesis of 1,4-butanediamine

Publications (2)

Publication Number Publication Date
EA200700329A1 true EA200700329A1 (ru) 2007-08-31
EA010179B1 EA010179B1 (ru) 2008-06-30

Family

ID=34928370

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700329A EA010179B1 (ru) 2004-07-15 2005-07-11 Биохимический синтез 1,4-бутандиамина

Country Status (18)

Country Link
US (1) US8497098B2 (ru)
EP (2) EP2949755B1 (ru)
JP (1) JP4836948B2 (ru)
CN (1) CN101010433B (ru)
AU (1) AU2005261861B2 (ru)
BR (1) BRPI0513343B1 (ru)
CA (1) CA2571528C (ru)
DK (1) DK1784496T3 (ru)
EA (1) EA010179B1 (ru)
ES (1) ES2581244T3 (ru)
IN (1) IN2007DE00479A (ru)
MX (1) MX2007000566A (ru)
MY (1) MY152156A (ru)
NZ (1) NZ552631A (ru)
TW (1) TWI346139B (ru)
UA (1) UA90479C2 (ru)
WO (1) WO2006005603A1 (ru)
ZA (1) ZA200700104B (ru)

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EP2049675A1 (de) 2006-08-01 2009-04-22 Basf Se Verfahren zur herstellung von pentamethylen-1,5-diisocyanat
CN101063144B (zh) * 2007-05-10 2010-09-15 南京农业大学 乳酸菌谷氨酸脱羧酶基因的克隆、表达及应用
US8334411B2 (en) 2008-03-12 2012-12-18 Toray Industries, Inc. Process for producing diamine and polyamide
AU2009234625B2 (en) * 2008-04-10 2012-07-19 Korea Advanced Institute Of Science And Technology Mutant microorganisms having high ability to produce putrescine and method for producing putrescine using the same
FR2933414B1 (fr) * 2008-07-07 2010-08-13 Arkema France Polyamide, composition comprenant un tel polyamide et leurs utilisations
BR112012001617B1 (pt) 2009-07-24 2019-06-18 Dsm Ip Assets B.V. Preparação de 1,4-diaminobutano
US8377666B2 (en) * 2009-10-13 2013-02-19 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
KR101174267B1 (ko) * 2010-01-06 2012-08-14 씨제이제일제당 (주) Ｌ-오르니틴 또는 ｌ-아르기닌 생산 변이주 및 이의 제조방법
KR101348461B1 (ko) * 2010-12-08 2014-01-08 씨제이제일제당 (주) 퓨트레신을 생산하는 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법
KR101286158B1 (ko) * 2011-08-24 2013-07-15 씨제이제일제당 (주) 발효액에서 1,4-디아미노부탄의 분리 및 정제하는 방법
US9677099B2 (en) * 2012-01-11 2017-06-13 Cj Cheiledang Corporation Recombinant microorganisms with an improved productivity of putrescine and method for producing putrescine using the same
ES2682696T3 (es) 2012-01-20 2018-09-21 Cj Cheiljedang Corporation Microorganismo recombinante con productividad de putrescina mejorada, y procedimiento de producción de putrescina utilizando el mismo
KR20140052189A (ko) * 2012-10-22 2014-05-07 씨제이제일제당 (주) 1,4-디아미노부탄의 정제방법, 상기 방법으로 정제된 1,4-디아미노부탄 및 이로부터 제조되는 폴리아미드
KR101607741B1 (ko) * 2013-03-20 2016-03-31 씨제이제일제당 (주) 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법
KR101835164B1 (ko) * 2013-07-17 2018-03-06 씨제이제일제당 (주) 향상된 퓨트레신 생산능을 가지는 변이된 오르니틴 디카복실레이즈 단백질 및 이의 용도
CN103951504A (zh) * 2014-04-21 2014-07-30 扬州市嘉康菇业发展有限公司 一种促进金针菇菌丝体快速生长的培养基的制备方法
WO2015163592A1 (ko) 2014-04-25 2015-10-29 씨제이제일제당 (주) 다이아민 생산 미생물 및 이를 이용한 다이아민 생산방법
AU2015250431B2 (en) 2014-04-25 2017-09-28 Cj Cheiljedang Corporation Microorganisms for Producing Putrescine and Process for Producing Putrescine Using Them
BR112016024958A2 (pt) 2014-04-25 2017-10-24 Cj Cheiljedang Corp micro-organismos para produção de diamina e processo para produção de diamina utilizando os mesmos
JP2017158434A (ja) * 2014-07-22 2017-09-14 協同乳業株式会社 バクテリア混合培養によるプトレッシン製造方法
KR101813759B1 (ko) 2015-06-24 2018-01-02 씨제이제일제당 (주) 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법
KR101735935B1 (ko) * 2015-07-20 2017-05-16 씨제이제일제당 (주) 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법
KR102011394B1 (ko) 2017-07-19 2019-10-22 씨제이제일제당 주식회사 퓨트레신을 생산하는 미생물 및 이를 이용한 퓨트레신 생산방법
EP3808848A1 (en) 2019-10-14 2021-04-21 Eberhard Karls Universität Tübingen Regulatory element of an arginine decarboxylase gene and methods and uses thereof
KR102246288B1 (ko) 2020-08-13 2021-04-29 씨제이제일제당 주식회사 퓨트레신 생산 미생물 및 이를 이용한 퓨트레신 생산방법
CN113061562B (zh) * 2021-03-22 2022-09-27 江南大学 一种利用钝齿棒杆菌发酵生产1,4-丁二胺的方法

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US2130948A (en) 1937-04-09 1938-09-20 Du Pont Synthetic fiber
ES2088826B1 (es) 1995-02-10 1997-06-01 Taguidell Sociedad Limitada Procedimiento de obtencion de las diaminas putrescina y cadaverina a partir de productos naturales tratados, su uso como aditivo en abonos, y abono correspondiente.
AU6464100A (en) * 1999-08-10 2001-03-05 John Innes Centre Polyamine accumulation in plants
JP2002345496A (ja) * 2001-05-25 2002-12-03 Ajinomoto Co Inc アグマチンの製造方法およびアルギニン脱炭酸酵素の製造方法

Also Published As

Publication number Publication date
BRPI0513343B1 (pt) 2020-11-03
AU2005261861A1 (en) 2006-01-19
JP4836948B2 (ja) 2011-12-14
ES2581244T3 (es) 2016-09-02
CN101010433B (zh) 2012-03-07
NZ552631A (en) 2009-09-25
US20090011478A1 (en) 2009-01-08
CN101010433A (zh) 2007-08-01
MX2007000566A (es) 2007-04-02
TW200605869A (en) 2006-02-16
JP2008505651A (ja) 2008-02-28
EA010179B1 (ru) 2008-06-30
BRPI0513343A (pt) 2008-05-06
ZA200700104B (en) 2008-05-28
DK1784496T3 (en) 2016-07-25
US8497098B2 (en) 2013-07-30
EP2949755A1 (en) 2015-12-02
IN2007DE00479A (ru) 2007-08-17
EP2949755B1 (en) 2018-03-28
AU2005261861B2 (en) 2010-08-26
CA2571528A1 (en) 2006-01-19
MY152156A (en) 2014-08-15
WO2006005603A1 (en) 2006-01-19
TWI346139B (en) 2011-08-01
UA90479C2 (en) 2010-05-11
EP1784496A1 (en) 2007-05-16
CA2571528C (en) 2016-02-16
EP1784496B1 (en) 2016-04-06

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU