EA200501250A1 - Композиция, содержащая смесь активных начал, и способ ее получения - Google Patents

Композиция, содержащая смесь активных начал, и способ ее получения

Info

Publication number
EA200501250A1
EA200501250A1 EA200501250A EA200501250A EA200501250A1 EA 200501250 A1 EA200501250 A1 EA 200501250A1 EA 200501250 A EA200501250 A EA 200501250A EA 200501250 A EA200501250 A EA 200501250A EA 200501250 A1 EA200501250 A1 EA 200501250A1
Authority
EA
Eurasian Patent Office
Prior art keywords
active
mixture
beginnings
obtaining
composition containing
Prior art date
Application number
EA200501250A
Other languages
English (en)
Other versions
EA010972B1 (ru
Inventor
Филипп Шеневье
Доминик Марешаль
Original Assignee
Этифарм
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Этифарм filed Critical Этифарм
Publication of EA200501250A1 publication Critical patent/EA200501250A1/ru
Publication of EA010972B1 publication Critical patent/EA010972B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/003—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Cosmetics (AREA)

Abstract

Изобретение относится к композиции, состоящей из смеси активных начал, и к способу ее получения, а именно, к основанной на активных началах частице с покрытием, в которой и ядро, и покрытие содержат активное начало, при этом ядро содержит первое активное начало, в то время как покрытие содержит второе активное начало, отличающееся по своей природе от первого.Отчет о международном поиске был опубликован 2004.10.28.
EA200501250A 2003-02-05 2004-01-21 Композиция, содержащая смесь активных начал, и способ ее получения EA010972B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0301308A FR2850576B1 (fr) 2003-02-05 2003-02-05 Composition comprenant un melange de principes actifs, et procede de preparation
US44719803P 2003-02-13 2003-02-13
PCT/EP2004/050035 WO2004069135A2 (en) 2003-02-05 2004-01-21 Composition comprising a mixture of active principles, and method of preparation

Publications (2)

Publication Number Publication Date
EA200501250A1 true EA200501250A1 (ru) 2006-02-24
EA010972B1 EA010972B1 (ru) 2008-12-30

Family

ID=32852330

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501250A EA010972B1 (ru) 2003-02-05 2004-01-21 Композиция, содержащая смесь активных начал, и способ ее получения

Country Status (19)

Country Link
US (2) US7846460B2 (ru)
EP (1) EP1589954B1 (ru)
JP (1) JP4791348B2 (ru)
KR (1) KR20050096963A (ru)
CN (1) CN1747723B (ru)
AU (1) AU2004210438B2 (ru)
BR (1) BRPI0407116B1 (ru)
CA (1) CA2514446C (ru)
EA (1) EA010972B1 (ru)
ES (1) ES2590807T3 (ru)
FR (1) FR2850576B1 (ru)
HK (1) HK1087015A1 (ru)
IL (1) IL169880A (ru)
IS (1) IS7998A (ru)
MX (1) MXPA05008161A (ru)
NO (1) NO341294B1 (ru)
NZ (1) NZ541886A (ru)
PL (1) PL223347B1 (ru)
WO (1) WO2004069135A2 (ru)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201509943A (zh) 2004-03-30 2015-03-16 Euro Celtique Sa 含有小於２５ｐｐｍ１４-羥可待因酮之羥可酮鹽酸鹽之組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝
US8163114B2 (en) * 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
BRPI0614143A2 (pt) 2005-08-02 2012-11-20 Sol Gel Technologies Ltd processo para revestir um material particulado insolével em Água, sàlido, com um àxido metÁlico, material particulado revestido, composiÇço, mÉtodo para o tratamento de uma condiÇço superficial em um induvÍduo, e, uso de material particulado revestido
FR2897267A1 (fr) * 2006-02-16 2007-08-17 Flamel Technologies Sa Formes pharmaceutiques multimicroparticulaires pour administration per os
MX2009001294A (es) * 2006-08-04 2009-05-21 Ethypharm Sa Granulo y tableta que se desintegra por vía oral que comprende oxicodona.
PL3103448T3 (pl) * 2006-09-26 2019-12-31 Novartis Ag Kompozycje farmaceutyczne zawierające modulator S1P
WO2008089774A1 (fr) * 2007-01-22 2008-07-31 Crd Saidal Formulation d'un comprime orodispersible a base de paracetamol enrobe
MX2009008250A (es) 2007-02-01 2009-08-27 Sol Gel Technologies Ltd Composiciones para aplicacion topica que comprenden un peroxido y retinoide.
MY151207A (en) * 2007-12-27 2014-04-30 Taiho Pharmaceutical Co Ltd Oral particulate antitumor preparation
AR076540A1 (es) * 2009-05-01 2011-06-22 Eurand Inc Composiciones de comprimidos de desintegracion oral que comprenden combinaciones de analgesicos no- opioides y opioides, forma de dosificacion. metodo de preparacion. metodo para tratar dolor
CN102526124B (zh) * 2011-01-31 2013-11-20 成都科尔医药技术有限公司 一种中药粉体及其制备方法
EP2819653B1 (en) 2012-03-02 2017-01-11 Rhodes Pharmaceuticals L.P. Tamper resistant immediate release formulations
WO2014042120A1 (ja) * 2012-09-13 2014-03-20 ライオン株式会社 発泡性口腔用組成物、発泡性口腔用固形製剤及び発泡性口腔用製品
CA2888278A1 (en) * 2012-10-15 2014-04-24 Isa Odidi Oral drug delivery formulations
KR101484608B1 (ko) * 2012-11-26 2015-01-22 한국과학기술연구원 Pva와 알지네이트 기반 코어-쉘 구조의 복합담체 및 그 제조방법
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
JP6513031B2 (ja) 2013-02-01 2019-05-15 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 液体テクノロジーのための担体としての多孔質シリカゲル
CA2919892C (en) 2013-08-12 2019-06-18 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9707184B2 (en) 2014-07-17 2017-07-18 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
EP3209282A4 (en) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
CN111990641A (zh) * 2020-05-06 2020-11-27 焦作百仑斯生物科技有限公司 一种解酒护肝片及施工方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000044404A (ja) * 1998-07-27 2000-02-15 Otsuka Chem Co Ltd 農業用混合粒剤
CA2259727A1 (en) * 1999-01-18 2000-07-18 Bernard Charles Sherman A two-layer pharmaceutical tablet comprising an nsaid and misoprostol
US6296874B1 (en) * 2000-05-01 2001-10-02 Aeropharm Technology Incorporated Core formulation comprising troglitazone and abiguanide
US6451342B2 (en) * 2000-05-01 2002-09-17 Aeropharm Technology Incorporated Core formulation comprised of troglitazone and a biguanide
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
WO2004060355A1 (en) * 2002-12-26 2004-07-22 Pozen Inc. Multilayer Dosage Forms Containing NSAIDs and Triptans

Also Published As

Publication number Publication date
US20060134422A1 (en) 2006-06-22
EA010972B1 (ru) 2008-12-30
NO341294B1 (no) 2017-10-02
PL376465A1 (en) 2005-12-27
CA2514446A1 (en) 2004-08-19
WO2004069135A2 (en) 2004-08-19
NZ541886A (en) 2008-12-24
IL169880A0 (en) 2007-07-04
JP2006516597A (ja) 2006-07-06
BRPI0407116A (pt) 2006-01-10
EP1589954A2 (en) 2005-11-02
CA2514446C (en) 2012-04-10
IS7998A (is) 2005-08-25
NO20053799L (no) 2005-08-11
AU2004210438B2 (en) 2007-08-16
WO2004069135A3 (en) 2004-10-28
MXPA05008161A (es) 2005-10-05
KR20050096963A (ko) 2005-10-06
JP4791348B2 (ja) 2011-10-12
AU2004210438A1 (en) 2004-08-19
CN1747723A (zh) 2006-03-15
HK1087015A1 (en) 2006-10-06
IL169880A (en) 2013-10-31
FR2850576A1 (fr) 2004-08-06
CN1747723B (zh) 2010-05-12
PL223347B1 (pl) 2016-10-31
EP1589954B1 (en) 2016-08-31
FR2850576B1 (fr) 2007-03-23
ES2590807T3 (es) 2016-11-23
US20110081389A1 (en) 2011-04-07
US7846460B2 (en) 2010-12-07
BRPI0407116B1 (pt) 2018-04-03

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU