FR2850576B1 - Composition comprenant un melange de principes actifs, et procede de preparation - Google Patents

Composition comprenant un melange de principes actifs, et procede de preparation

Info

Publication number
FR2850576B1
FR2850576B1 FR0301308A FR0301308A FR2850576B1 FR 2850576 B1 FR2850576 B1 FR 2850576B1 FR 0301308 A FR0301308 A FR 0301308A FR 0301308 A FR0301308 A FR 0301308A FR 2850576 B1 FR2850576 B1 FR 2850576B1
Authority
FR
France
Prior art keywords
preparing
mixture
composition
same
active ingredients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR0301308A
Other languages
English (en)
Other versions
FR2850576A1 (fr
Inventor
Philippe Chenevier
Dominique Marechal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethypharm SAS
Original Assignee
Ethypharm SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0301308A priority Critical patent/FR2850576B1/fr
Application filed by Ethypharm SAS filed Critical Ethypharm SAS
Priority to KR1020057014021A priority patent/KR20050096963A/ko
Priority to BRPI0407116-6A priority patent/BRPI0407116B1/pt
Priority to MXPA05008161A priority patent/MXPA05008161A/es
Priority to JP2006501987A priority patent/JP4791348B2/ja
Priority to ZA200506028A priority patent/ZA200506028B/en
Priority to ES04703798.1T priority patent/ES2590807T3/es
Priority to NZ541886A priority patent/NZ541886A/en
Priority to PCT/EP2004/050035 priority patent/WO2004069135A2/fr
Priority to CA2514446A priority patent/CA2514446C/fr
Priority to EA200501250A priority patent/EA010972B1/ru
Priority to AU2004210438A priority patent/AU2004210438B2/en
Priority to EP04703798.1A priority patent/EP1589954B1/fr
Priority to US10/544,311 priority patent/US7846460B2/en
Priority to PL376465A priority patent/PL223347B1/pl
Priority to CN200480003558XA priority patent/CN1747723B/zh
Publication of FR2850576A1 publication Critical patent/FR2850576A1/fr
Priority to IL169880A priority patent/IL169880A/en
Priority to NO20053799A priority patent/NO341294B1/no
Priority to IS7998A priority patent/IS7998A/is
Priority to HK06107140.8A priority patent/HK1087015A1/xx
Application granted granted Critical
Publication of FR2850576B1 publication Critical patent/FR2850576B1/fr
Priority to US12/947,551 priority patent/US20110081389A1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/003—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer
FR0301308A 2003-02-05 2003-02-05 Composition comprenant un melange de principes actifs, et procede de preparation Expired - Lifetime FR2850576B1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR0301308A FR2850576B1 (fr) 2003-02-05 2003-02-05 Composition comprenant un melange de principes actifs, et procede de preparation
PL376465A PL223347B1 (pl) 2003-02-05 2004-01-21 Kompozycja farmaceutyczna albo kosmetyczna zawierająca powlekane cząstki
US10/544,311 US7846460B2 (en) 2003-02-05 2004-01-21 Composition comprising a mixture of active principles, and method of preparation
JP2006501987A JP4791348B2 (ja) 2003-02-05 2004-01-21 有効成分の混合物を含む組成物および調製の方法
BRPI0407116-6A BRPI0407116B1 (pt) 2003-02-05 2004-01-21 Partícula revestida baseada em princípio ativo, composição farmacêutica ou cosmética, e, método para produção de partícula revestida baseada em princípio ativo
ES04703798.1T ES2590807T3 (es) 2003-02-05 2004-01-21 Composición que comprende una mezcla de principios activos y procedimiento de preparación
NZ541886A NZ541886A (en) 2003-02-05 2004-01-21 Composition comprising a mixture of active principles, and method of preparation
CN200480003558XA CN1747723B (zh) 2003-02-05 2004-01-21 含活性成分混合物的组合物及其制备方法
CA2514446A CA2514446C (fr) 2003-02-05 2004-01-21 Composition comprenant un melange de principes actifs et methode pour la preparer
EA200501250A EA010972B1 (ru) 2003-02-05 2004-01-21 Композиция, содержащая смесь активных начал, и способ ее получения
KR1020057014021A KR20050096963A (ko) 2003-02-05 2004-01-21 유효 성분 혼합물을 포함하는 조성물 및 이의 제조 방법
EP04703798.1A EP1589954B1 (fr) 2003-02-05 2004-01-21 Composition comprenant un melange de principes actifs, et procede pour la preparer
MXPA05008161A MXPA05008161A (es) 2003-02-05 2004-01-21 Composicion que comprende una mezcla de principios activos, y metodo de preparacion.
ZA200506028A ZA200506028B (en) 2003-02-05 2004-01-21 Composition comprising a mixture of active principles, and method of preparation
PCT/EP2004/050035 WO2004069135A2 (fr) 2003-02-05 2004-01-21 Composition comprenant un melange de principes actifs, et procede pour la preparer
AU2004210438A AU2004210438B2 (en) 2003-02-05 2004-01-21 Composition comprising a mixture of active principles, and method of preparation
IL169880A IL169880A (en) 2003-02-05 2005-07-26 Preparations manufactured from particles with a coating containing active substance in the particle and coating and their preparation processes
NO20053799A NO341294B1 (no) 2003-02-05 2005-08-11 Blanding innbefattende blanding av aktive bestanddeler og en fremgangsmåte ved fremstilling derav
IS7998A IS7998A (is) 2003-02-05 2005-08-25 Samsetning sem inniheldur blöndu af virkum þáttumog aðferð til að framleiða hana
HK06107140.8A HK1087015A1 (en) 2003-02-05 2006-06-22 Composition comprising a mixture of active principles, and method of preparation
US12/947,551 US20110081389A1 (en) 2003-02-05 2010-11-16 Composition comprising a mixture of active principles, and method of preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0301308A FR2850576B1 (fr) 2003-02-05 2003-02-05 Composition comprenant un melange de principes actifs, et procede de preparation
US44719803P 2003-02-13 2003-02-13

Publications (2)

Publication Number Publication Date
FR2850576A1 FR2850576A1 (fr) 2004-08-06
FR2850576B1 true FR2850576B1 (fr) 2007-03-23

Family

ID=32852330

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0301308A Expired - Lifetime FR2850576B1 (fr) 2003-02-05 2003-02-05 Composition comprenant un melange de principes actifs, et procede de preparation

Country Status (19)

Country Link
US (2) US7846460B2 (fr)
EP (1) EP1589954B1 (fr)
JP (1) JP4791348B2 (fr)
KR (1) KR20050096963A (fr)
CN (1) CN1747723B (fr)
AU (1) AU2004210438B2 (fr)
BR (1) BRPI0407116B1 (fr)
CA (1) CA2514446C (fr)
EA (1) EA010972B1 (fr)
ES (1) ES2590807T3 (fr)
FR (1) FR2850576B1 (fr)
HK (1) HK1087015A1 (fr)
IL (1) IL169880A (fr)
IS (1) IS7998A (fr)
MX (1) MXPA05008161A (fr)
NO (1) NO341294B1 (fr)
NZ (1) NZ541886A (fr)
PL (1) PL223347B1 (fr)
WO (1) WO2004069135A2 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201509943A (zh) 2004-03-30 2015-03-16 Euro Celtique Sa 含有小於２５ｐｐｍ１４-羥可待因酮之羥可酮鹽酸鹽之組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝
US8163114B2 (en) * 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
AU2006274541B2 (en) 2005-08-02 2012-12-13 Sol-Gel Technologies Ltd. Metal oxide coating of water insoluble ingredients
FR2897267A1 (fr) * 2006-02-16 2007-08-17 Flamel Technologies Sa Formes pharmaceutiques multimicroparticulaires pour administration per os
WO2008015220A1 (fr) * 2006-08-04 2008-02-07 Ethypharm Granulés et comprimés comprenant de l'oxycodone et se désintégrant par voie orale
AU2007302296A1 (en) * 2006-09-26 2008-04-03 Novartis Ag Pharmaceutical compositions comprising an S1P modulator
WO2008089774A1 (fr) * 2007-01-22 2008-07-31 Crd Saidal Formulation d'un comprime orodispersible a base de paracetamol enrobe
KR20090125243A (ko) 2007-02-01 2009-12-04 솔-겔 테크놀로지스 리미티드 퍼옥사이드 및 레티노이드를 함유하는 국소 도포용 조성물
US20100266706A1 (en) * 2007-12-27 2010-10-21 Taiho Pharmaceutical Co., Ltd. Oral particulate antitumor preparation
TW201041608A (en) * 2009-05-01 2010-12-01 Eurand Inc Orally disintegrating tablet compositions comprising combinations of high and low-dose drugs
CN102526124B (zh) * 2011-01-31 2013-11-20 成都科尔医药技术有限公司 一种中药粉体及其制备方法
AU2013203493B2 (en) * 2012-03-02 2016-02-04 Rhodes Pharmaceuticals L.P. Tamper resistant immediate release formulations
WO2014042120A1 (fr) * 2012-09-13 2014-03-20 ライオン株式会社 Composition orale de formation de mousse, préparation solide orale de formation de mousse et produit oral de formation de mousse
CA2888278A1 (fr) * 2012-10-15 2014-04-24 Isa Odidi Formulations de medicament pour administration par voie orale
KR101484608B1 (ko) * 2012-11-26 2015-01-22 한국과학기술연구원 Pva와 알지네이트 기반 코어-쉘 구조의 복합담체 및 그 제조방법
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
PL2950923T3 (pl) 2013-02-01 2022-04-04 W.R. Grace & Co. - Conn. Porowaty żel krzemionkowy jako nośnik płynnych technologii
AU2014306759B2 (en) 2013-08-12 2018-04-26 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (fr) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Comprimé extrudé anti-abus à libération prolongée
WO2016010771A1 (fr) 2014-07-17 2016-01-21 Pharmaceutical Manufacturing Research Services, Inc. Forme posologique remplie de liquide anti-abus à libération immédiate
EP3209282A4 (fr) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Forme galénique anti-abus de remplissage de liquide à libération prolongée
CN111990641A (zh) * 2020-05-06 2020-11-27 焦作百仑斯生物科技有限公司 一种解酒护肝片及施工方法

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Publication number Priority date Publication date Assignee Title
JP2000044404A (ja) * 1998-07-27 2000-02-15 Otsuka Chem Co Ltd 農業用混合粒剤
CA2259727A1 (fr) * 1999-01-18 2000-07-18 Bernard Charles Sherman Pastille pharmaceutique a deux couches comprenant un ains et du misoprostol
US6296874B1 (en) * 2000-05-01 2001-10-02 Aeropharm Technology Incorporated Core formulation comprising troglitazone and abiguanide
US6451342B2 (en) * 2000-05-01 2002-09-17 Aeropharm Technology Incorporated Core formulation comprised of troglitazone and a biguanide
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
WO2004060355A1 (fr) * 2002-12-26 2004-07-22 Pozen Inc. Formes galeniques multicouches contenant des ains et des triptanes

Also Published As

Publication number Publication date
KR20050096963A (ko) 2005-10-06
EA010972B1 (ru) 2008-12-30
IS7998A (is) 2005-08-25
CA2514446A1 (fr) 2004-08-19
CN1747723A (zh) 2006-03-15
ES2590807T3 (es) 2016-11-23
NO341294B1 (no) 2017-10-02
EP1589954B1 (fr) 2016-08-31
MXPA05008161A (es) 2005-10-05
IL169880A (en) 2013-10-31
CN1747723B (zh) 2010-05-12
BRPI0407116B1 (pt) 2018-04-03
PL376465A1 (en) 2005-12-27
US7846460B2 (en) 2010-12-07
AU2004210438A1 (en) 2004-08-19
JP4791348B2 (ja) 2011-10-12
US20060134422A1 (en) 2006-06-22
JP2006516597A (ja) 2006-07-06
AU2004210438B2 (en) 2007-08-16
HK1087015A1 (en) 2006-10-06
EP1589954A2 (fr) 2005-11-02
IL169880A0 (en) 2007-07-04
FR2850576A1 (fr) 2004-08-06
PL223347B1 (pl) 2016-10-31
NO20053799L (no) 2005-08-11
NZ541886A (en) 2008-12-24
WO2004069135A3 (fr) 2004-10-28
BRPI0407116A (pt) 2006-01-10
WO2004069135A2 (fr) 2004-08-19
CA2514446C (fr) 2012-04-10
US20110081389A1 (en) 2011-04-07
EA200501250A1 (ru) 2006-02-24

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