EA200500091A1 - Фосфатные соли карведилола и/или их сольваты, соответствующие композиции и/или способы лечения - Google Patents

Фосфатные соли карведилола и/или их сольваты, соответствующие композиции и/или способы лечения

Info

Publication number
EA200500091A1
EA200500091A1 EA200500091A EA200500091A EA200500091A1 EA 200500091 A1 EA200500091 A1 EA 200500091A1 EA 200500091 A EA200500091 A EA 200500091A EA 200500091 A EA200500091 A EA 200500091A EA 200500091 A1 EA200500091 A1 EA 200500091A1
Authority
EA
Eurasian Patent Office
Prior art keywords
solvates
carvedilol
treatment methods
phosphate salts
salts
Prior art date
Application number
EA200500091A
Other languages
English (en)
Other versions
EA008384B1 (ru
Inventor
Кристофер С. Брук
Вей Чен
Филип К. Делль'Орсо
Ли М. Катринчич
Энн Мари Лоувет
Чоон К. Ох
Пол Дж. Сперрс
Кристофер Вернер
Original Assignee
Эс Би ФАРМКО ПУЭРТО РИКО ИНК.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30000823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200500091(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Эс Би ФАРМКО ПУЭРТО РИКО ИНК. filed Critical Эс Би ФАРМКО ПУЭРТО РИКО ИНК.
Publication of EA200500091A1 publication Critical patent/EA200500091A1/ru
Publication of EA008384B1 publication Critical patent/EA008384B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Настоящее изобретение относится к фосфатным солям карведилола, которые включают в себя новые кристаллические формы дигидрофосфата карведилола (т.е. дигидрофосфатную соль 1-(карбазол-4-илокси-3-[[2-(o-метоксифенокси)этил]амино]-2-пропанола) и/или гидрофосфат карведилола и тому подобное) и/или их сольваты, композиции, содержащие вышеуказанные соли и/или сольваты, и способы использования вышеуказанных солей и/или сольватов для лечения гипертензии, застойной сердечной недостаточности, стенокардии и тому подобное.Отчет о международном поиске был опубликован 2004.06.03.
EA200500091A 2002-06-27 2003-06-27 Фосфатные соли карведилола, их сольваты, композиции и способы лечения гипертензии, застойной сердечной недостаточности или стенокардии EA008384B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39217502P 2002-06-27 2002-06-27
PCT/US2003/020408 WO2004002419A2 (en) 2002-06-27 2003-06-27 Carvedilol phosphate salts and/or solvates thereof, correspondinq compositions, and/or methods of treatment

Publications (2)

Publication Number Publication Date
EA200500091A1 true EA200500091A1 (ru) 2005-10-27
EA008384B1 EA008384B1 (ru) 2007-04-27

Family

ID=30000823

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500091A EA008384B1 (ru) 2002-06-27 2003-06-27 Фосфатные соли карведилола, их сольваты, композиции и способы лечения гипертензии, застойной сердечной недостаточности или стенокардии

Country Status (15)

Country Link
US (6) US7268156B2 (ru)
EP (1) EP1534270A4 (ru)
JP (3) JP2005533823A (ru)
KR (3) KR20140006111A (ru)
CN (6) CN103288714A (ru)
AU (1) AU2003248746B2 (ru)
BR (1) BR0312102A (ru)
CA (1) CA2492060C (ru)
EA (1) EA008384B1 (ru)
IL (1) IL165814A (ru)
MX (1) MXPA04012923A (ru)
NO (1) NO329710B1 (ru)
NZ (1) NZ537161A (ru)
WO (1) WO2004002419A2 (ru)
ZA (1) ZA200410011B (ru)

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Also Published As

Publication number Publication date
AU2003248746A1 (en) 2004-01-19
CA2492060C (en) 2011-11-01
KR20140006111A (ko) 2014-01-15
CN103254114A (zh) 2013-08-21
US7759384B2 (en) 2010-07-20
CA2492060A1 (en) 2004-01-08
US7893100B2 (en) 2011-02-22
US20070259940A1 (en) 2007-11-08
WO2004002419A2 (en) 2004-01-08
US20050240027A1 (en) 2005-10-27
WO2004002419A3 (en) 2004-06-03
BR0312102A (pt) 2007-05-29
JP2013241450A (ja) 2013-12-05
ZA200410011B (en) 2006-07-26
CN103333099A (zh) 2013-10-02
CN103288715A (zh) 2013-09-11
US20070244181A1 (en) 2007-10-18
NZ537161A (en) 2007-09-28
CN101898995A (zh) 2010-12-01
US7268156B2 (en) 2007-09-11
US20080262069A1 (en) 2008-10-23
AU2003248746B2 (en) 2009-01-08
US20070244182A1 (en) 2007-10-18
US7902378B2 (en) 2011-03-08
IL165814A0 (en) 2006-01-15
JP2005533823A (ja) 2005-11-10
EP1534270A2 (en) 2005-06-01
US20070238774A1 (en) 2007-10-11
EA008384B1 (ru) 2007-04-27
CN1678305A (zh) 2005-10-05
EP1534270A4 (en) 2006-05-17
NO329710B1 (no) 2010-12-06
JP2011088917A (ja) 2011-05-06
US7626041B2 (en) 2009-12-01
JP5422545B2 (ja) 2014-02-19
CN103288714A (zh) 2013-09-11
NO20050427L (no) 2005-01-25
CN101898995B (zh) 2013-05-01
IL165814A (en) 2012-05-31
MXPA04012923A (es) 2005-03-31
KR20110134952A (ko) 2011-12-15
KR20130042047A (ko) 2013-04-25
KR101468827B1 (ko) 2014-12-03

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