EA200200635A1 - Флуоресцентный контрастный агент для ближней инфракрасной области спектра и способ флуоресцентной визуализации - Google Patents
Флуоресцентный контрастный агент для ближней инфракрасной области спектра и способ флуоресцентной визуализацииInfo
- Publication number
- EA200200635A1 EA200200635A1 EA200200635A EA200200635A EA200200635A1 EA 200200635 A1 EA200200635 A1 EA 200200635A1 EA 200200635 A EA200200635 A EA 200200635A EA 200200635 A EA200200635 A EA 200200635A EA 200200635 A1 EA200200635 A1 EA 200200635A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- contrast agent
- near infrared
- spectrum
- fluorescent
- infrared region
- Prior art date
Links
- 239000002872 contrast media Substances 0.000 title abstract 6
- 238000002329 infrared spectrum Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000012800 visualization Methods 0.000 title 1
- 238000001228 spectrum Methods 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005284 excitation Effects 0.000 abstract 1
- 238000001917 fluorescence detection Methods 0.000 abstract 1
- 238000000799 fluorescence microscopy Methods 0.000 abstract 1
- 230000001678 irradiating effect Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 125000000542 sulfonic acid group Chemical group 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1999/009959 WO2001043781A1 (en) | 1999-12-15 | 1999-12-15 | Near infrared fluorescent contrast agent and fluorescence imaging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200200635A1 true EA200200635A1 (ru) | 2002-12-26 |
Family
ID=8167530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200200635A EA200200635A1 (ru) | 1999-12-15 | 1999-12-15 | Флуоресцентный контрастный агент для ближней инфракрасной области спектра и способ флуоресцентной визуализации |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1237583A1 (zh) |
| JP (1) | JP2003517025A (zh) |
| KR (1) | KR20020082207A (zh) |
| CN (1) | CN1217701C (zh) |
| AU (1) | AU2097500A (zh) |
| BG (1) | BG106822A (zh) |
| BR (1) | BR9917587A (zh) |
| CA (1) | CA2394539C (zh) |
| EA (1) | EA200200635A1 (zh) |
| EE (1) | EE200200321A (zh) |
| HU (1) | HUP0204024A2 (zh) |
| IL (1) | IL149798A0 (zh) |
| MX (1) | MXPA02005806A (zh) |
| NO (1) | NO328630B1 (zh) |
| PL (1) | PL355891A1 (zh) |
| SK (1) | SK8142002A3 (zh) |
| TR (1) | TR200201567T2 (zh) |
| WO (1) | WO2001043781A1 (zh) |
| YU (1) | YU44402A (zh) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7682602B2 (en) * | 2003-12-19 | 2010-03-23 | Konica Minolta Medical & Graphic, Inc. | Near-infrared fluorescent contrast medium |
| JP2005220045A (ja) * | 2004-02-04 | 2005-08-18 | Konica Minolta Medical & Graphic Inc | 蛍光造影剤 |
| JP5074044B2 (ja) * | 2007-01-18 | 2012-11-14 | オリンパス株式会社 | 蛍光観察装置および蛍光観察装置の作動方法 |
| WO2009023813A1 (en) * | 2007-08-15 | 2009-02-19 | Applied Soil Water Technologies Llc | Metals recovery from mining heap leach ore |
| US20090214436A1 (en) | 2008-02-18 | 2009-08-27 | Washington University | Dichromic fluorescent compounds |
| DK2470887T3 (da) | 2009-08-28 | 2020-04-06 | Visen Medical Inc | Systemer til tomografisk billeddannelse i diffuse medier ved at anvende en hybrid inversionsteknik |
| JP2011046663A (ja) | 2009-08-28 | 2011-03-10 | Fujifilm Corp | 近赤外蛍光造影剤 |
| WO2011038006A1 (en) | 2009-09-22 | 2011-03-31 | Visen Medical, Inc. | Systems and methods for virtual index-matching of diffusive media |
| CA2787129A1 (en) * | 2010-01-14 | 2011-07-21 | The Regents Of The University Of California | Devices, systems and methods to detect and reduce or prevent entry of inflammatory mediators into milk ducts |
| GB201010878D0 (en) | 2010-06-29 | 2010-08-11 | Ge Healthcare As | Dye compositiion and dye syntheses |
| EP3553075A1 (en) | 2012-01-23 | 2019-10-16 | Washington University | Goggle imaging systems and methods |
| CN104853669B (zh) | 2012-10-15 | 2017-07-21 | 文森医学公司 | 具有荧光及生物发光源的交叉形态加权特征的漫射介质成像的系统、方法及设备 |
| US20170232119A1 (en) | 2013-03-15 | 2017-08-17 | Purdue Research Foundation | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors |
| AU2013383382B2 (en) | 2013-03-15 | 2017-02-23 | Purdue Research Foundation | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors |
| CN113349707A (zh) | 2013-12-31 | 2021-09-07 | 纪念斯隆-凯特琳癌症中心 | 用于荧光源实时多通道成像的系统、方法和设备 |
| CN107249647A (zh) | 2014-12-15 | 2017-10-13 | 纪念斯隆-凯特琳癌症中心 | 具有增强的神经结合选择性的环状肽、与所述环状肽结合的纳米颗粒和此二者用于实时体内神经组织成像的用途 |
| US10806804B2 (en) | 2015-05-06 | 2020-10-20 | Washington University | Compounds having RD targeting motifs and methods of use thereof |
| CN107949385B (zh) | 2015-06-03 | 2021-04-09 | 瑟吉麦博股份公司 | 荧光缀合物 |
| CN105222828B (zh) * | 2015-09-30 | 2017-05-24 | 东南大学 | 一种贴壁射流速度场和浓度场的同步测量装置与方法 |
| KR20180093961A (ko) | 2015-12-15 | 2018-08-22 | 메모리얼 슬로안-케터링 캔서 센터 | 조직 구별, 예를 들어, 수술 중 시각화를 위한 영상화 시스템 및 방법 |
| EP3548096A1 (en) | 2016-11-30 | 2019-10-09 | Memorial Sloan Kettering Cancer Center | Inhibitor-functionalized ultrasmall nanoparticles and methods thereof |
| CA3095410A1 (en) | 2018-03-30 | 2019-10-03 | Perkinelmer Health Sciences, Inc. | Systems and methods for 3d reconstruction of anatomical organs and inclusions using short-wave infrared (swir) projection tomography |
| EP4072598A4 (en) | 2019-12-13 | 2024-02-21 | Washington University | NEAR-INFRARED FLUORESCENT DYES, FORMULATIONS AND ASSOCIATED METHODS |
| US11964965B2 (en) * | 2020-05-08 | 2024-04-23 | On Target Laboratories, LLC | Methods of manufacture and synthesis of fluorescent dye compounds and uses thereof |
| EP4015004A1 (en) | 2020-12-18 | 2022-06-22 | Phi Pharma SA | Proteoglycan specific branched peptides |
| CN114459862A (zh) * | 2022-01-13 | 2022-05-10 | 华腾实业（深圳）股份有限公司 | 一种高识别的真菌荧光染色液 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0529002B1 (en) * | 1990-05-15 | 2001-10-04 | Hyperion, Inc. | Fluorescent porphyrin, and fluorescent phthalocyanine - polyethylene glycol, polyol, and saccharide derivatives as fluorescent probes |
| CN1093768C (zh) * | 1995-01-30 | 2002-11-06 | 第一化学药品株式会社 | 诊断用标记物 |
| JP2000095758A (ja) * | 1998-09-18 | 2000-04-04 | Schering Ag | 近赤外蛍光造影剤および蛍光造影方法 |
-
1999
- 1999-12-15 BR BR9917587-8A patent/BR9917587A/pt not_active Application Discontinuation
- 1999-12-15 EE EEP200200321A patent/EE200200321A/xx unknown
- 1999-12-15 SK SK814-2002A patent/SK8142002A3/sk unknown
- 1999-12-15 EP EP99965468A patent/EP1237583A1/en not_active Withdrawn
- 1999-12-15 YU YU44402A patent/YU44402A/sh unknown
- 1999-12-15 AU AU20975/00A patent/AU2097500A/en not_active Abandoned
- 1999-12-15 WO PCT/EP1999/009959 patent/WO2001043781A1/en not_active Application Discontinuation
- 1999-12-15 EA EA200200635A patent/EA200200635A1/ru unknown
- 1999-12-15 CN CN998170437A patent/CN1217701C/zh not_active Expired - Fee Related
- 1999-12-15 IL IL14979899A patent/IL149798A0/xx not_active IP Right Cessation
- 1999-12-15 CA CA002394539A patent/CA2394539C/en not_active Expired - Fee Related
- 1999-12-15 MX MXPA02005806A patent/MXPA02005806A/es unknown
- 1999-12-15 KR KR1020027007635A patent/KR20020082207A/ko not_active Application Discontinuation
- 1999-12-15 TR TR2002/01567T patent/TR200201567T2/xx unknown
- 1999-12-15 PL PL99355891A patent/PL355891A1/xx not_active Application Discontinuation
- 1999-12-15 HU HU0204024A patent/HUP0204024A2/hu unknown
- 1999-12-15 JP JP2001544917A patent/JP2003517025A/ja active Pending
-
2002
- 2002-06-13 BG BG106822A patent/BG106822A/bg unknown
- 2002-06-14 NO NO20022837A patent/NO328630B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003517025A (ja) | 2003-05-20 |
| IL149798A0 (en) | 2002-11-10 |
| AU2097500A (en) | 2001-06-25 |
| WO2001043781A1 (en) | 2001-06-21 |
| CA2394539A1 (en) | 2001-06-21 |
| HUP0204024A2 (en) | 2003-04-28 |
| MXPA02005806A (es) | 2010-10-26 |
| EE200200321A (et) | 2003-10-15 |
| BG106822A (bg) | 2003-01-31 |
| TR200201567T2 (tr) | 2002-11-21 |
| NO20022837D0 (no) | 2002-06-14 |
| NO328630B1 (no) | 2010-04-12 |
| BR9917587A (pt) | 2002-08-06 |
| CA2394539C (en) | 2009-10-27 |
| SK8142002A3 (en) | 2002-12-03 |
| CN1384760A (zh) | 2002-12-11 |
| YU44402A (sh) | 2005-03-15 |
| NO20022837L (no) | 2002-06-14 |
| CN1217701C (zh) | 2005-09-07 |
| KR20020082207A (ko) | 2002-10-30 |
| EP1237583A1 (en) | 2002-09-11 |
| PL355891A1 (en) | 2004-05-31 |
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