EA032943B1 - Способ получения терапевтических наночастиц (варианты) и терапевтическая наночастица (варианты) - Google Patents

Способ получения терапевтических наночастиц (варианты) и терапевтическая наночастица (варианты)

Info

Publication number
EA032943B1
EA032943B1 EA201590583A EA201590583A EA032943B1 EA 032943 B1 EA032943 B1 EA 032943B1 EA 201590583 A EA201590583 A EA 201590583A EA 201590583 A EA201590583 A EA 201590583A EA 032943 B1 EA032943 B1 EA 032943B1
Authority
EA
Eurasian Patent Office
Prior art keywords
therapeutic
preparing
nanoparticles
nanoparticle
therapeutic nanoparticles
Prior art date
Application number
EA201590583A
Other languages
English (en)
Russian (ru)
Other versions
EA201590583A1 (ru
Inventor
Мария Фигуэйредо
Эрик Пик
Дэвид Дьюитт
Кристина Ван Ген Ховен
Грег Трояно
Джеймс Райт
Юнг-Хо Сонг
Хун Ван
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49274868&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA032943(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA201590583A1 publication Critical patent/EA201590583A1/ru
Publication of EA032943B1 publication Critical patent/EA032943B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201590583A 2012-09-17 2013-09-16 Способ получения терапевтических наночастиц (варианты) и терапевтическая наночастица (варианты) EA032943B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261702037P 2012-09-17 2012-09-17
PCT/US2013/059936 WO2014043618A1 (en) 2012-09-17 2013-09-16 Process for preparing therapeutic nanoparticles

Publications (2)

Publication Number Publication Date
EA201590583A1 EA201590583A1 (ru) 2015-11-30
EA032943B1 true EA032943B1 (ru) 2019-08-30

Family

ID=49274868

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590583A EA032943B1 (ru) 2012-09-17 2013-09-16 Способ получения терапевтических наночастиц (варианты) и терапевтическая наночастица (варианты)

Country Status (22)

Country Link
US (1) US9877923B2 (cg-RX-API-DMAC7.html)
EP (1) EP2895156B1 (cg-RX-API-DMAC7.html)
JP (1) JP6356678B2 (cg-RX-API-DMAC7.html)
KR (1) KR20150056618A (cg-RX-API-DMAC7.html)
CN (1) CN104812381B (cg-RX-API-DMAC7.html)
AU (1) AU2013315118B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015005940A2 (cg-RX-API-DMAC7.html)
CA (1) CA2885193C (cg-RX-API-DMAC7.html)
DK (1) DK2895156T3 (cg-RX-API-DMAC7.html)
EA (1) EA032943B1 (cg-RX-API-DMAC7.html)
ES (1) ES2732377T3 (cg-RX-API-DMAC7.html)
HU (1) HUE043998T2 (cg-RX-API-DMAC7.html)
IL (1) IL237780A0 (cg-RX-API-DMAC7.html)
MX (1) MX356097B (cg-RX-API-DMAC7.html)
MY (1) MY179194A (cg-RX-API-DMAC7.html)
NZ (1) NZ705812A (cg-RX-API-DMAC7.html)
PL (1) PL2895156T3 (cg-RX-API-DMAC7.html)
PT (1) PT2895156T (cg-RX-API-DMAC7.html)
SG (1) SG11201502065UA (cg-RX-API-DMAC7.html)
SI (1) SI2895156T1 (cg-RX-API-DMAC7.html)
TR (1) TR201909389T4 (cg-RX-API-DMAC7.html)
WO (1) WO2014043618A1 (cg-RX-API-DMAC7.html)

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