UA115135C2 - Катіонні полімери на основі глікогену - Google Patents

Катіонні полімери на основі глікогену

Info

Publication number
UA115135C2
UA115135C2 UAA201406638A UAA201406638A UA115135C2 UA 115135 C2 UA115135 C2 UA 115135C2 UA A201406638 A UAA201406638 A UA A201406638A UA A201406638 A UAA201406638 A UA A201406638A UA 115135 C2 UA115135 C2 UA 115135C2
Authority
UA
Ukraine
Prior art keywords
cationic polymers
glycogen
based cationic
complexes
anionic compounds
Prior art date
Application number
UAA201406638A
Other languages
English (en)
Inventor
Вінченцо Руссо
Еліза Лібераті
Нікола Каццолла
Original Assignee
Ацьєнде Кіміке Ріуніте Анджеліні Франческо А.Чі.Р.А.Ф. С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ацьєнде Кіміке Ріуніте Анджеліні Франческо А.Чі.Р.А.Ф. С.П.А. filed Critical Ацьєнде Кіміке Ріуніте Анджеліні Франческо А.Чі.Р.А.Ф. С.П.А.
Publication of UA115135C2 publication Critical patent/UA115135C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/18—Reserve carbohydrates, e.g. glycogen, inulin, laminarin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Даний винахід стосується катіонних полімерів на основі глікогену, комплексів зазначених катіонних полімерів з аніонними сполуками, фармацевтичних композицій, що містять зазначені комплекси, та застосування зазначених комплексів для доставки або трансфектування зазначених аніонних сполук у специфічну фармакологічну ціль, таку як, наприклад, орган, тканина або клітина.
UAA201406638A 2012-03-15 2013-02-21 Катіонні полімери на основі глікогену UA115135C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12159710 2012-03-15
PCT/EP2013/053422 WO2013135471A1 (en) 2012-03-15 2013-02-21 Glycogen-based cationic polymers

Publications (1)

Publication Number Publication Date
UA115135C2 true UA115135C2 (uk) 2017-09-25

Family

ID=47739282

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201406638A UA115135C2 (uk) 2012-03-15 2013-02-21 Катіонні полімери на основі глікогену

Country Status (29)

Country Link
US (1) US9717801B2 (uk)
EP (1) EP2825565B1 (uk)
JP (1) JP6247234B2 (uk)
KR (1) KR101997018B1 (uk)
CN (2) CN104080812B (uk)
AR (1) AR090307A1 (uk)
AU (1) AU2013231561B2 (uk)
BR (1) BR112014018617A8 (uk)
CA (1) CA2859273C (uk)
CY (1) CY1121829T1 (uk)
DK (1) DK2825565T3 (uk)
EA (1) EA032479B1 (uk)
ES (1) ES2732216T3 (uk)
GE (1) GEP201606581B (uk)
HK (1) HK1203984A1 (uk)
HR (1) HRP20191114T1 (uk)
HU (1) HUE045049T2 (uk)
IL (1) IL233823B (uk)
LT (1) LT2825565T (uk)
ME (1) ME03429B (uk)
MX (1) MX351599B (uk)
PL (1) PL2825565T3 (uk)
PT (1) PT2825565T (uk)
RS (1) RS58985B1 (uk)
SG (2) SG10201607577QA (uk)
SI (1) SI2825565T1 (uk)
TR (1) TR201909387T4 (uk)
UA (1) UA115135C2 (uk)
WO (1) WO2013135471A1 (uk)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR095937A1 (es) 2013-04-05 2015-11-25 Acraf Potenciador de la solubilidad en agua a base de glucógeno
KR102214865B1 (ko) 2013-04-26 2021-02-15 마이렉서스 바이오테크놀로지스 인코퍼레이티드 파이토글리코겐 나노입자와 이를 제조하는 방법
WO2016108264A1 (ja) * 2014-12-29 2016-07-07 株式会社ボナック 核酸分子を安定に含有する組成物
CN104558246B (zh) * 2015-01-20 2017-03-01 武汉理工大学 一种叶酸/生物素修饰的壳聚糖材料及其制备方法
DE102015205088B4 (de) * 2015-03-20 2021-03-04 Kuka Deutschland Gmbh Verfahren zum Ermitteln eines Kalibrierungsparameters eines Fahrzeuges sowie Fahrzeug hierzu
JP6872782B2 (ja) * 2016-03-08 2021-05-19 国立大学法人京都大学 カチオン性グルカンナノスフェア、複合体、核酸導入剤及びがん治療剤
AU2017251217A1 (en) * 2016-04-14 2018-11-08 Mirexus Biotechnologies Inc. Anti-infective compositions comprising phytoglycogen nanoparticles
WO2017190248A1 (en) * 2016-05-04 2017-11-09 Mirexus Biotechnologies Inc. Glycogen and phytoglycogen nanoparticles as immunosuppressive compounds, and compositions and methods of use thereof
CN105949344B (zh) * 2016-05-13 2019-05-17 中山大学 一种阳离子超支化多糖衍生物及其在增强血卟啉类光敏剂对肿瘤细胞光毒性方面的应用
WO2019027999A1 (en) * 2017-07-31 2019-02-07 Ohio State Innovation Foundation BIOMIMETIC NANOMATERIALS AND USES THEREOF
WO2019140304A1 (en) * 2018-01-11 2019-07-18 Virgina Tech Intellectual Properties Inc. Amphiphilic polysacchardides,polysaccharide-based hydrogels, and methods of manufacture

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IT1255488B (it) 1992-08-04 1995-11-06 Angelini Francesco Ist Ricerca Polisaccaridi del glicogeno
US7144713B1 (en) 1995-10-02 2006-12-05 Emd Biosciences, Inc. Method for precipitating nucleic acid with visible carrier
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EP1399189A1 (en) 2001-06-11 2004-03-24 Universite De Montreal Compositions and methods for enhancing nucleic acid transfer into cells
US20030147958A1 (en) 2002-01-29 2003-08-07 Cheol-Hee Ahn Biodegradable multi-block copolymers of poly(amino acid)s and poly(ethylene glycol) for the delivery of bioactive agents
WO2003078576A2 (en) 2002-03-12 2003-09-25 Nitto Denko Corporation Vector for transfection of eukaryotic cells
EP1738769A4 (en) * 2004-03-31 2011-03-09 Medgel Corp PREPARATION FOR THE TRANSFER OF NUCLEIC ACID INTO A CELL
WO2007038769A1 (en) 2005-09-28 2007-04-05 Hetzel Adrian H Electro-hydraulic timed angle controlled joint simulation torque calibration, certification and analysis device
UA97559C2 (uk) * 2007-11-08 2012-02-27 Оцука Фармасьютікал Ко., Лтд. Комплекс нуклеїнової кислоти і композиція для доставки нуклеїнової кислоти
CN101235098A (zh) * 2008-01-09 2008-08-06 浙江大学 功能性植物多糖的修饰方法
CN102257116B (zh) * 2008-12-22 2013-02-06 荷兰联合利华有限公司 洗衣组合物
EP2366009B1 (en) * 2008-12-22 2012-10-24 Unilever PLC Laundry compositions
JP5649224B2 (ja) * 2009-05-08 2015-01-07 江崎グリコ株式会社 グルクロン酸含有グルカン、その製造法および利用
EP2275085A1 (en) * 2009-07-07 2011-01-19 University of Rostock Biodegradable copolymer suitable for delivering nucleic acid materials into cells
CN102068698A (zh) * 2009-11-24 2011-05-25 深圳先进技术研究院 纳米疫苗及其制备方法

Also Published As

Publication number Publication date
WO2013135471A1 (en) 2013-09-19
CN107236052A (zh) 2017-10-10
US20140378532A1 (en) 2014-12-25
SI2825565T1 (sl) 2019-08-30
LT2825565T (lt) 2019-07-10
IL233823B (en) 2018-05-31
RS58985B1 (sr) 2019-08-30
BR112014018617A8 (pt) 2017-07-11
SG10201607577QA (en) 2016-11-29
CN107236052B (zh) 2019-09-24
MX2014010698A (es) 2015-03-10
AU2013231561B2 (en) 2017-06-08
BR112014018617A2 (uk) 2017-06-20
HK1203984A1 (en) 2015-11-06
JP6247234B2 (ja) 2017-12-13
CA2859273A1 (en) 2013-09-19
EP2825565A1 (en) 2015-01-21
MX351599B (es) 2017-10-20
PL2825565T3 (pl) 2019-10-31
US9717801B2 (en) 2017-08-01
DK2825565T3 (da) 2019-06-24
SG11201403816YA (en) 2014-08-28
TR201909387T4 (tr) 2019-07-22
ME03429B (me) 2020-01-20
IL233823A0 (en) 2014-09-30
JP2015510020A (ja) 2015-04-02
AU2013231561A1 (en) 2014-07-10
EA032479B1 (ru) 2019-06-28
ES2732216T3 (es) 2019-11-21
AR090307A1 (es) 2014-11-05
HUE045049T2 (hu) 2019-12-30
PT2825565T (pt) 2019-07-10
EP2825565B1 (en) 2019-04-03
KR20150006414A (ko) 2015-01-16
CN104080812A (zh) 2014-10-01
CN104080812B (zh) 2017-06-27
CY1121829T1 (el) 2020-07-31
HRP20191114T1 (hr) 2019-09-20
CA2859273C (en) 2020-04-14
GEP201606581B (en) 2016-11-25
KR101997018B1 (ko) 2019-07-05
EA201491613A1 (ru) 2014-12-30

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