EA031154B1 - Новый препарат, противодействующий злоупотреблению лекарством - Google Patents
Новый препарат, противодействующий злоупотреблению лекарством Download PDFInfo
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- EA031154B1 EA031154B1 EA201101281A EA201101281A EA031154B1 EA 031154 B1 EA031154 B1 EA 031154B1 EA 201101281 A EA201101281 A EA 201101281A EA 201101281 A EA201101281 A EA 201101281A EA 031154 B1 EA031154 B1 EA 031154B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- preparation according
- active substance
- film
- mixture
- filler
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- HUNXMJYCHXQEGX-UHFFFAOYSA-N zaleplon Chemical compound CCN(C(C)=O)C1=CC=CC(C=2N3N=CC(=C3N=CC=2)C#N)=C1 HUNXMJYCHXQEGX-UHFFFAOYSA-N 0.000 description 1
- 229960004010 zaleplon Drugs 0.000 description 1
- 229910052726 zirconium Inorganic materials 0.000 description 1
- 229910001928 zirconium oxide Inorganic materials 0.000 description 1
- 229960000820 zopiclone Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2009000592 | 2009-03-04 | ||
| PCT/GB2010/000374 WO2010100414A1 (en) | 2009-03-04 | 2010-03-02 | Abuse resistant formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201101281A1 EA201101281A1 (ru) | 2012-02-28 |
| EA031154B1 true EA031154B1 (ru) | 2018-11-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201101281A EA031154B1 (ru) | 2009-03-04 | 2010-03-02 | Новый препарат, противодействующий злоупотреблению лекарством |
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| EP (1) | EP2403482B1 (enExample) |
| JP (1) | JP5728705B2 (enExample) |
| KR (1) | KR101751906B1 (enExample) |
| CN (1) | CN102341096B (enExample) |
| AU (1) | AU2010219449B2 (enExample) |
| BR (1) | BRPI1009121A2 (enExample) |
| CA (1) | CA2753664C (enExample) |
| DK (1) | DK2403482T3 (enExample) |
| EA (1) | EA031154B1 (enExample) |
| ES (1) | ES2660674T3 (enExample) |
| IL (1) | IL214583A (enExample) |
| MX (1) | MX336355B (enExample) |
| NO (1) | NO2403482T3 (enExample) |
| NZ (1) | NZ594513A (enExample) |
| PL (1) | PL2403482T3 (enExample) |
| WO (1) | WO2010100414A1 (enExample) |
Families Citing this family (24)
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| EP2393484A1 (en) | 2009-02-06 | 2011-12-14 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
| EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
| US12186426B2 (en) | 2009-10-30 | 2025-01-07 | Ix Biopharma Ltd. | Solid dosage form |
| CN102933207B (zh) | 2009-10-30 | 2018-02-02 | Ix生物医药有限公司 | 快速溶解固体剂型 |
| EP3446685A1 (en) * | 2012-11-30 | 2019-02-27 | Acura Pharmaceuticals, Inc. | Self-regulated release of active pharmaceutical ingredient |
| US10420729B2 (en) | 2013-03-15 | 2019-09-24 | R.P. Scherer Technologies, Llc | Abuse resistant capsule |
| AU2014306759B2 (en) | 2013-08-12 | 2018-04-26 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2016010771A1 (en) | 2014-07-17 | 2016-01-21 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| CA2964628A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| CA3018328A1 (en) | 2014-10-31 | 2016-04-30 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| GB201502073D0 (en) | 2015-02-09 | 2015-03-25 | Cubic Pharmaceuticals Ltd And Delta Pharmaceuticals Ltd | HDEG technology |
| WO2016140961A1 (en) | 2015-03-02 | 2016-09-09 | Mc10, Inc. | Perspiration sensor |
| WO2017149287A1 (en) * | 2016-02-29 | 2017-09-08 | Emplicure Ab | Devices for evaporation and inhalation of active agents |
| EP3210596A1 (en) * | 2016-02-29 | 2017-08-30 | G.L. Pharma GmbH | Abuse-deterrent pharmaceutical composition |
| CN105997907A (zh) * | 2016-05-16 | 2016-10-12 | 胡小丽 | 高血压治疗药丸 |
| CN105997915A (zh) * | 2016-05-16 | 2016-10-12 | 张阳 | 一种高血压治疗用缓释片剂 |
| CN105769798A (zh) * | 2016-05-16 | 2016-07-20 | 张阳 | 一种高血压治疗药物的制备方法 |
| US9650338B1 (en) | 2016-07-29 | 2017-05-16 | VDM Biochemicals, Inc. | Opioid antagonist compounds and methods of making and using |
| GB201714412D0 (en) * | 2017-09-07 | 2017-10-25 | Emplicure Ab | Evaporation devices containing plant material |
| CN108720990A (zh) * | 2018-06-04 | 2018-11-02 | 界首市龙鑫生物科技有限公司 | 一种能够加快伤口愈合的医用冷敷贴 |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| CA3246974A1 (en) * | 2022-04-01 | 2023-10-05 | EMPLICURE AB (publ) | ALKALINE INTRAORAL PRODUCTS |
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-
2010
- 2010-03-02 WO PCT/GB2010/000374 patent/WO2010100414A1/en not_active Ceased
- 2010-03-02 MX MX2011009214A patent/MX336355B/es unknown
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- 2010-03-02 DK DK10711246.8T patent/DK2403482T3/en active
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- 2010-03-02 NO NO10711246A patent/NO2403482T3/no unknown
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- 2010-03-02 PL PL10711246T patent/PL2403482T3/pl unknown
- 2010-03-02 EA EA201101281A patent/EA031154B1/ru not_active IP Right Cessation
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| EP0265061A1 (en) * | 1986-09-18 | 1988-04-27 | London School of Pharmacy Innovations Ltd | Pharmaceutical formulation |
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Also Published As
| Publication number | Publication date |
|---|---|
| DK2403482T3 (en) | 2018-03-05 |
| EA201101281A1 (ru) | 2012-02-28 |
| US10543203B2 (en) | 2020-01-28 |
| ES2660674T3 (es) | 2018-03-23 |
| KR20110122838A (ko) | 2011-11-11 |
| NO2403482T3 (enExample) | 2018-05-26 |
| US20120015007A1 (en) | 2012-01-19 |
| US9622972B2 (en) | 2017-04-18 |
| BRPI1009121A2 (pt) | 2018-06-19 |
| CN102341096A (zh) | 2012-02-01 |
| MX2011009214A (es) | 2011-09-28 |
| JP2012519675A (ja) | 2012-08-30 |
| IL214583A0 (en) | 2011-09-27 |
| US20170239229A1 (en) | 2017-08-24 |
| CN102341096B (zh) | 2015-02-18 |
| KR101751906B1 (ko) | 2017-06-29 |
| EP2403482A1 (en) | 2012-01-11 |
| AU2010219449A1 (en) | 2011-09-01 |
| JP5728705B2 (ja) | 2015-06-03 |
| IL214583A (en) | 2016-04-21 |
| MX336355B (es) | 2016-01-14 |
| EP2403482B1 (en) | 2017-12-27 |
| PL2403482T3 (pl) | 2018-06-29 |
| WO2010100414A1 (en) | 2010-09-10 |
| CA2753664C (en) | 2019-11-05 |
| AU2010219449B2 (en) | 2014-12-18 |
| NZ594513A (en) | 2013-10-25 |
| CA2753664A1 (en) | 2010-09-10 |
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| Publication | Publication Date | Title |
|---|---|---|
| EA031154B1 (ru) | Новый препарат, противодействующий злоупотреблению лекарством | |
| US10736838B2 (en) | Transdermal drug administration device | |
| JP5691051B2 (ja) | ジオポリマー結合剤を含む持続薬物送達用組成物 | |
| HK1164705B (en) | Abuse resistant formulation | |
| HK1164705A (en) | Abuse resistant formulation | |
| HK1167601B (en) | Composition for sustained drug delivery comprising geopolymeric binder | |
| HK1167601A (en) | Composition for sustained drug delivery comprising geopolymeric binder |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |