EA028171B1 - Способ получения высокочистой калиевой соли азилсартана медоксомила - Google Patents

Способ получения высокочистой калиевой соли азилсартана медоксомила Download PDF

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Publication number
EA028171B1
EA028171B1 EA201590657A EA201590657A EA028171B1 EA 028171 B1 EA028171 B1 EA 028171B1 EA 201590657 A EA201590657 A EA 201590657A EA 201590657 A EA201590657 A EA 201590657A EA 028171 B1 EA028171 B1 EA 028171B1
Authority
EA
Eurasian Patent Office
Prior art keywords
azilsartan medoxomil
solvate
dimethylacetamide
potassium salt
methylpyrrolidone
Prior art date
Application number
EA201590657A
Other languages
English (en)
Russian (ru)
Other versions
EA201590657A1 (ru
Inventor
Ян Стах
Радим Крулис
Йосеф Церны
Лудек Ридван
Ондрей Даммер
Лукас Крейцик
Станислав Радл
Original Assignee
Зентива К.С.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Зентива К.С. filed Critical Зентива К.С.
Publication of EA201590657A1 publication Critical patent/EA201590657A1/ru
Publication of EA028171B1 publication Critical patent/EA028171B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
EA201590657A 2012-09-26 2013-09-25 Способ получения высокочистой калиевой соли азилсартана медоксомила EA028171B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ2012-663A CZ305318B6 (cs) 2012-09-26 2012-09-26 Způsob přípravy vysoce čisté draselné soli azilsartanu medoxomilu
PCT/CZ2013/000114 WO2014048404A1 (en) 2012-09-26 2013-09-25 A method of preparing a highly pure potassium salt of azilsartan medoxomil

Publications (2)

Publication Number Publication Date
EA201590657A1 EA201590657A1 (ru) 2015-08-31
EA028171B1 true EA028171B1 (ru) 2017-10-31

Family

ID=66624776

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590657A EA028171B1 (ru) 2012-09-26 2013-09-25 Способ получения высокочистой калиевой соли азилсартана медоксомила

Country Status (12)

Country Link
EP (1) EP2900662A1 (ko)
JP (1) JP2015532267A (ko)
KR (1) KR20150060733A (ko)
CN (1) CN104662019A (ko)
BR (1) BR112015006572A2 (ko)
CZ (1) CZ305318B6 (ko)
EA (1) EA028171B1 (ko)
HK (1) HK1205505A1 (ko)
IL (1) IL237884A0 (ko)
MX (1) MX2015003209A (ko)
UA (1) UA113668C2 (ko)
WO (1) WO2014048404A1 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2014702A3 (cs) * 2014-10-15 2016-04-27 Zentiva, K.S. Způsob přípravy vysoce čistého azilsartanu
CN105753854A (zh) * 2014-12-16 2016-07-13 重庆朗天制药有限公司 一种阿齐沙坦酯钾盐的新制备方法
CN109071519A (zh) * 2016-01-28 2018-12-21 株式会社德山 阿齐沙坦及其制造方法
CN108727356A (zh) * 2018-06-28 2018-11-02 江苏新瑞药业有限公司 一种奥美沙坦酯碱金属盐的合成方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050187269A1 (en) * 2004-02-25 2005-08-25 Takeda Pharmaceutical Company Limited Benzimidazole derivative and use thereof
WO2013042067A1 (en) * 2011-09-20 2013-03-28 Ranbaxy Laboratories Limited Process for the preparation of potassium salt of azilsartan medoxomil
WO2013104342A1 (en) * 2012-01-14 2013-07-18 Sunshine Lake Pharma Co., Ltd. Crystalline forms of azilsartan medoxomil potassium and preparation and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012090043A1 (en) * 2010-12-29 2012-07-05 Jubilant Life Sciences Limited Novel solid state forms of azilsartan medoxomil and preparation thereof
JP2014505097A (ja) * 2011-02-08 2014-02-27 ジュビラント ライフ サイエンセズ リミテッド アジルサルタンメドキソミルの改良製造方法
CZ2012274A3 (cs) * 2012-04-19 2013-10-30 Zentiva, K.S. Zpusob prípravy vysoce cisté draselné soli azilsartanu medoxomilu

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050187269A1 (en) * 2004-02-25 2005-08-25 Takeda Pharmaceutical Company Limited Benzimidazole derivative and use thereof
WO2013042067A1 (en) * 2011-09-20 2013-03-28 Ranbaxy Laboratories Limited Process for the preparation of potassium salt of azilsartan medoxomil
WO2013104342A1 (en) * 2012-01-14 2013-07-18 Sunshine Lake Pharma Co., Ltd. Crystalline forms of azilsartan medoxomil potassium and preparation and uses thereof

Also Published As

Publication number Publication date
KR20150060733A (ko) 2015-06-03
BR112015006572A2 (pt) 2017-07-04
JP2015532267A (ja) 2015-11-09
UA113668C2 (uk) 2017-02-27
CN104662019A (zh) 2015-05-27
CZ305318B6 (cs) 2015-07-29
EP2900662A1 (en) 2015-08-05
IL237884A0 (en) 2015-05-31
MX2015003209A (es) 2015-07-14
HK1205505A1 (en) 2015-12-18
EA201590657A1 (ru) 2015-08-31
CZ2012663A3 (cs) 2014-04-02
WO2014048404A1 (en) 2014-04-03

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM RU