EA027160B1 - Модифицированные белки и пептиды - Google Patents
Модифицированные белки и пептиды Download PDFInfo
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- EA027160B1 EA027160B1 EA201490262A EA201490262A EA027160B1 EA 027160 B1 EA027160 B1 EA 027160B1 EA 201490262 A EA201490262 A EA 201490262A EA 201490262 A EA201490262 A EA 201490262A EA 027160 B1 EA027160 B1 EA 027160B1
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- amino acid
- binding
- terminal
- immunoglobulin
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Applications Claiming Priority (6)
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| US201161524488P | 2011-08-17 | 2011-08-17 | |
| GBGB1121226.3A GB201121226D0 (en) | 2011-12-12 | 2011-12-12 | Modified proteins and peptides |
| GBGB1121233.9A GB201121233D0 (en) | 2011-12-12 | 2011-12-12 | Modified proteins and peptides |
| GBGB1121236.2A GB201121236D0 (en) | 2011-12-12 | 2011-12-12 | Proteins and peptides |
| PCT/EP2012/064632 WO2013014208A2 (en) | 2011-07-27 | 2012-07-25 | Antigen binding constructs |
| PCT/EP2012/065782 WO2013024059A2 (en) | 2011-08-17 | 2012-08-13 | Modified proteins and peptides |
Publications (2)
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| EA201490262A1 EA201490262A1 (ru) | 2014-09-30 |
| EA027160B1 true EA027160B1 (ru) | 2017-06-30 |
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| EA201490262A EA027160B1 (ru) | 2011-08-17 | 2012-08-13 | Модифицированные белки и пептиды |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US10843420B2 (en) | 2015-12-21 | 2020-11-24 | Hexcel Composites Limited | Relating to electrically conducting materials |
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| EP2621953B1 (en) | 2010-09-30 | 2017-04-05 | Ablynx N.V. | Biological materials related to c-met |
| US11644471B2 (en) | 2010-09-30 | 2023-05-09 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| EP2944654A1 (en) * | 2011-06-23 | 2015-11-18 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains |
| ES2759936T3 (es) | 2011-06-23 | 2020-05-12 | Ablynx Nv | Proteínas de unión a albúmina sérica |
| EP4350345A3 (en) * | 2011-06-23 | 2024-07-24 | Ablynx N.V. | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains |
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| KR102162413B1 (ko) * | 2011-08-17 | 2020-10-07 | 글락소 그룹 리미티드 | 변형된 단백질 및 펩티드 |
| US9346884B2 (en) | 2011-09-30 | 2016-05-24 | Ablynx N.V. | Biological materials related to c-Met |
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| US20140161796A1 (en) * | 2012-09-13 | 2014-06-12 | Andreas Loew | Single chain proteins with c-terminal modifications |
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| US11009511B2 (en) | 2014-05-16 | 2021-05-18 | Ablynx N.V. | Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies |
| DK3143042T3 (da) * | 2014-05-16 | 2020-08-31 | Ablynx Nv | Forbedrede variable immunoglobulindomæner |
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| CN107484416A (zh) * | 2014-09-26 | 2017-12-15 | 宏观基因有限公司 | 能够结合cd19和cd3的双特异性单价双抗体及其用途 |
| US10526397B2 (en) | 2015-01-21 | 2020-01-07 | Inhibrx, Inc. | Non-immunogenic single domain antibodies |
| EP3271391A1 (en) * | 2015-03-20 | 2018-01-24 | Ablynx N.V. | Glycosylated immunoglobulin single variable domains |
| ES2973042T3 (es) | 2015-03-31 | 2024-06-18 | Sorriso Pharmaceuticals Inc | Polipéptidos |
| WO2016156468A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Polypeptides |
| CN107427577A (zh) | 2015-03-31 | 2017-12-01 | 韦斯夸尔德有限公司 | 具有蛋白酶可切割接头的肽构建体 |
| RS61062B1 (sr) | 2015-07-16 | 2020-12-31 | Inhibrx Inc | Multivalentni i multispecifični dr5-vezujući fuzioni proteini |
| EP4218833A1 (en) | 2015-10-01 | 2023-08-02 | Whitehead Institute for Biomedical Research | Labeling of antibodies |
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| KR102220275B1 (ko) * | 2015-11-18 | 2021-02-26 | 머크 샤프 앤드 돔 코포레이션 | Pd1 및/또는 lag3 결합제 |
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| JP7046804B2 (ja) * | 2015-11-18 | 2022-04-04 | アブリンクス エン．ヴェー． | 改良された血清アルブミン結合剤 |
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| MX2019014331A (es) | 2017-05-31 | 2020-01-27 | Boehringer Ingelheim Int | Polipeptidos que antagonizan la se?alizacion wnt en celulas tumorales. |
| IL317013A (en) | 2017-09-08 | 2025-01-01 | Takeda Pharmaceuticals Co | Binding proteins are activated under limited conditions |
| EP3688030B1 (en) * | 2017-09-27 | 2024-12-11 | Elasmogen Ltd | Specific binding molecules |
| CA3089211A1 (en) * | 2018-02-06 | 2019-08-15 | Ablynx Nv | Methods of treating initial episode of ttp with immunoglobulin single variable domains |
| EP3569618A1 (en) | 2018-05-19 | 2019-11-20 | Boehringer Ingelheim International GmbH | Antagonizing cd73 antibody |
| TWI848953B (zh) | 2018-06-09 | 2024-07-21 | 德商百靈佳殷格翰國際股份有限公司 | 針對癌症治療之多特異性結合蛋白 |
| EP3820891A1 (en) * | 2018-07-10 | 2021-05-19 | Regeneron Pharmaceuticals, Inc. | Modifying binding molecules to minimize pre-existing interactions |
| CN109096394B (zh) * | 2018-09-21 | 2021-11-05 | 成都阿帕克生物科技有限公司 | 一种抗葡萄球菌蛋白a的b亚单位的纳米抗体及核酸分子和应用 |
| FR3088640A1 (fr) | 2018-10-14 | 2020-05-22 | Smart Diagnostix Pharma | Nouveau polypeptide se liant specifiquement a la proteine p16 |
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AZ BY KZ TJ RU |