EA023697B1 - ПРИМЕНЕНИЕ КОМБИНАЦИИ ИЗ 7-(2,5-ДИГИДРО-4-ИМИДАЗО[1,2-а]ПИРИДИН-3-ИЛ-2,5-ДИОКСО-1Н-ПИРРОЛ-3-ИЛ)-9-ФТОР-1,2,3,4-ТЕТРАГИДРО-2-(1-ПИПЕРИДИНИЛКАРБОНИЛ)ПИРРОЛО[3,2,1-jk][1,4]БЕНЗОДИАЗЕПИНА И ХИМИОТЕРАПЕВТИЧЕСКОГО АГЕНТА ДЛЯ ПОЛУЧЕНИЯ ЛЕКАРСТВЕННОГО СРЕДСТВА ДЛЯ ЛЕЧЕНИЯ РАКА ЖЕЛУДКА - Google Patents
ПРИМЕНЕНИЕ КОМБИНАЦИИ ИЗ 7-(2,5-ДИГИДРО-4-ИМИДАЗО[1,2-а]ПИРИДИН-3-ИЛ-2,5-ДИОКСО-1Н-ПИРРОЛ-3-ИЛ)-9-ФТОР-1,2,3,4-ТЕТРАГИДРО-2-(1-ПИПЕРИДИНИЛКАРБОНИЛ)ПИРРОЛО[3,2,1-jk][1,4]БЕНЗОДИАЗЕПИНА И ХИМИОТЕРАПЕВТИЧЕСКОГО АГЕНТА ДЛЯ ПОЛУЧЕНИЯ ЛЕКАРСТВЕННОГО СРЕДСТВА ДЛЯ ЛЕЧЕНИЯ РАКА ЖЕЛУДКА Download PDFInfo
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- EA023697B1 EA023697B1 EA201201155A EA201201155A EA023697B1 EA 023697 B1 EA023697 B1 EA 023697B1 EA 201201155 A EA201201155 A EA 201201155A EA 201201155 A EA201201155 A EA 201201155A EA 023697 B1 EA023697 B1 EA 023697B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- compound
- fluoro
- imidazo
- dihydro
- mmol
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Landscapes
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| EA201070085A EA018447B1 (ru) | 2007-07-02 | 2008-06-20 | Применение комбинации 7-(2,5-дигидро-4-имидазо[1,2-а]пиридин-3-ил-2,5-диоксо-1н-пиррол-3-ил)-9-фтор-1,2,3,4-тетрагидро-2-(1-пиперидинилкарбонил)пирроло[3,2,1-jk][1,4]бензодиазепина с химиотерапевтическим агентом для лечения злокачественных опухолей |
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| SG175207A1 (en) * | 2009-04-14 | 2011-11-28 | Lilly Co Eli | Benzodiazepine derivative for the treatment of hematopoietic neoplasm and leukemia |
| US20150017245A1 (en) * | 2011-09-22 | 2015-01-15 | Bind Therapeutics, Inc. | Methods of treating cancers with therapeutic nanoparticles |
| TW201417817A (zh) * | 2012-09-25 | 2014-05-16 | Daiichi Sankyo Co Ltd | Ｇｓｋ３抑制劑與抗ｄｒ５抗體之組合 |
| WO2016175324A1 (ja) * | 2015-04-30 | 2016-11-03 | 大鵬薬品工業株式会社 | 抗腫瘍剤の副作用軽減剤 |
| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| US10016507B2 (en) * | 2016-03-02 | 2018-07-10 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: III |
| US10213511B2 (en) * | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US11066419B2 (en) * | 2016-12-30 | 2021-07-20 | Frequency Therapeutics, Inc. | 1H-pyrrole-2,5-dione compounds and methods of using same |
| EP3920885A1 (en) | 2019-02-08 | 2021-12-15 | Frequency Therapeutics, Inc. | Valproic acid compounds and wnt agonists for treating ear disorders |
| WO2022256656A1 (en) * | 2021-06-03 | 2022-12-08 | University Of Cincinnati | Bzd-1 as a chemosensitizer of cancer |
| CN113956157B (zh) * | 2021-11-18 | 2024-05-03 | 西安都创医药科技有限公司 | 一种合成2-甲酰基-1-环丙烷甲酸乙酯的方法 |
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| EP1788086A1 (en) * | 1997-03-17 | 2007-05-23 | Human Genome Sciences, Inc. | Death Domain Containing Receptor 5 |
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| GB8904161D0 (en) | 1989-02-23 | 1989-04-05 | Hoffmann La Roche | Substituted pyrroles |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
| CN1312154C (zh) * | 2002-03-05 | 2007-04-25 | 伊莱利利公司 | 作为激酶抑制剂的嘌呤衍生物 |
| EP1539756B1 (en) | 2002-09-19 | 2007-11-14 | Schering Corporation | Imidazopyridines as cyclin dependent kinase inhibitors |
| CN1980681A (zh) * | 2004-07-09 | 2007-06-13 | 新加坡科技研究局 | GSK－3β的调节及治疗增殖性病变的方法 |
| GB0418328D0 (en) * | 2004-08-17 | 2004-09-22 | Imp College Innovations Ltd | Cancer methods and medicaments |
| US20060252082A1 (en) * | 2005-05-04 | 2006-11-09 | University Of South Florida | Predicting treatment response in cancer subjects |
| TWI428132B (zh) * | 2007-07-02 | 2014-03-01 | Lilly Co Eli | 癌症化療效果之強化 |
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