NZ581355A - Potentiation of cancer chemotherapy by 7-(2,5-dihydro-4-imidazo[1,2-a]pyridine-3-yl-2,5-dioxo-1h-pyrrol-3-yl)-9-fluoro-1,2,3,4-tetrahydro-2-(1-piperidinyl-carbonyl)-pyrrolo[3,2,1-jk][1,4]benzodiazepine - Google Patents
Potentiation of cancer chemotherapy by 7-(2,5-dihydro-4-imidazo[1,2-a]pyridine-3-yl-2,5-dioxo-1h-pyrrol-3-yl)-9-fluoro-1,2,3,4-tetrahydro-2-(1-piperidinyl-carbonyl)-pyrrolo[3,2,1-jk][1,4]benzodiazepineInfo
- Publication number
- NZ581355A NZ581355A NZ581355A NZ58135508A NZ581355A NZ 581355 A NZ581355 A NZ 581355A NZ 581355 A NZ581355 A NZ 581355A NZ 58135508 A NZ58135508 A NZ 58135508A NZ 581355 A NZ581355 A NZ 581355A
- Authority
- NZ
- New Zealand
- Prior art keywords
- chemotherapeutic agent
- fluoro
- imidazo
- dihydro
- compound
- Prior art date
Links
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94751207P | 2007-07-02 | 2007-07-02 | |
| PCT/US2008/067614 WO2009006043A2 (en) | 2007-07-02 | 2008-06-20 | Potentiation of cancer chemotherapy by 7-(2,5-dihydro-4-imidazo [1,2-a]pyrine-3-yl-2,5-dioxo-ih-pyrrol-3-yl)-9-fluoro-1,2,3,4 tetrahydro-2-(1-piperidinyl-carbonyd-pyrrolo[3,2,1-jk][1,4]benzodiazepine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ581355A true NZ581355A (en) | 2012-04-27 |
Family
ID=39737054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ581355A NZ581355A (en) | 2007-07-02 | 2008-06-20 | Potentiation of cancer chemotherapy by 7-(2,5-dihydro-4-imidazo[1,2-a]pyridine-3-yl-2,5-dioxo-1h-pyrrol-3-yl)-9-fluoro-1,2,3,4-tetrahydro-2-(1-piperidinyl-carbonyl)-pyrrolo[3,2,1-jk][1,4]benzodiazepine |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8318713B2 (OSRAM) |
| EP (1) | EP2173348B1 (OSRAM) |
| JP (2) | JP5551589B2 (OSRAM) |
| KR (1) | KR101230085B1 (OSRAM) |
| CN (2) | CN102772416A (OSRAM) |
| AR (1) | AR067112A1 (OSRAM) |
| AU (1) | AU2008270732B2 (OSRAM) |
| BR (1) | BRPI0813789A2 (OSRAM) |
| CA (1) | CA2691587C (OSRAM) |
| CL (2) | CL2008001848A1 (OSRAM) |
| EA (2) | EA023697B1 (OSRAM) |
| ES (1) | ES2561202T3 (OSRAM) |
| IL (2) | IL202237A (OSRAM) |
| MA (1) | MA31677B1 (OSRAM) |
| MX (1) | MX2009013449A (OSRAM) |
| MY (1) | MY154472A (OSRAM) |
| NZ (1) | NZ581355A (OSRAM) |
| PE (1) | PE20090838A1 (OSRAM) |
| TW (1) | TWI428132B (OSRAM) |
| UA (1) | UA97400C2 (OSRAM) |
| WO (1) | WO2009006043A2 (OSRAM) |
| ZA (1) | ZA200908725B (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI428132B (zh) * | 2007-07-02 | 2014-03-01 | Lilly Co Eli | 癌症化療效果之強化 |
| PE20120772A1 (es) * | 2009-04-14 | 2012-06-27 | Lilly Co Eli | Derivado de benzodiazepina para el tratamiento de neoplasma hematopoyetico y leucemia |
| US20150017245A1 (en) * | 2011-09-22 | 2015-01-15 | Bind Therapeutics, Inc. | Methods of treating cancers with therapeutic nanoparticles |
| WO2014050779A1 (ja) * | 2012-09-25 | 2014-04-03 | 第一三共株式会社 | Ｇｓｋ３阻害剤と抗ｄｒ５抗体の組み合わせ |
| WO2016175324A1 (ja) * | 2015-04-30 | 2016-11-03 | 大鵬薬品工業株式会社 | 抗腫瘍剤の副作用軽減剤 |
| US10201540B2 (en) | 2016-03-02 | 2019-02-12 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: I |
| US10213511B2 (en) * | 2016-03-02 | 2019-02-26 | Frequency Therapeutics, Inc. | Thermoreversible compositions for administration of therapeutic agents |
| US10016507B2 (en) * | 2016-03-02 | 2018-07-10 | Frequency Therapeutics, Inc. | Solubilized compositions for controlled proliferation of stem cells / generating inner ear hair cells using GSK3 inhibitors: III |
| CN110392686A (zh) * | 2016-12-30 | 2019-10-29 | 频率治疗公司 | 1h-吡咯-2,5-二酮化合物以及使用它们来诱导干/祖支持细胞自我更新的方法 |
| AU2020218366A1 (en) | 2019-02-08 | 2021-09-16 | Frequency Therapeutics, Inc. | Valproic acid compounds and Wnt agonists for treating ear disorders |
| CA3222225A1 (en) * | 2021-06-03 | 2022-12-08 | University Of Cincinnati | Bzd-1 as a chemosensitizer of cancer |
| CN113956157B (zh) * | 2021-11-18 | 2024-05-03 | 西安都创医药科技有限公司 | 一种合成2-甲酰基-1-环丙烷甲酸乙酯的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8904161D0 (en) | 1989-02-23 | 1989-04-05 | Hoffmann La Roche | Substituted pyrroles |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| EP1788086A1 (en) * | 1997-03-17 | 2007-05-23 | Human Genome Sciences, Inc. | Death Domain Containing Receptor 5 |
| US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
| KR100974770B1 (ko) | 2002-03-05 | 2010-08-06 | 일라이 릴리 앤드 캄파니 | 키나제 억제제로서의 퓨린 유도체 |
| JP4845379B2 (ja) | 2002-09-19 | 2011-12-28 | シェーリング コーポレイション | サイクリン依存性キナーゼインヒビターとしてのイミダゾピリジン |
| EP1768679B1 (en) * | 2004-07-09 | 2012-08-22 | Agency for Science, Technology and Research | Modulation of gsk-3beta and method of treating proliferative disorders |
| GB0418328D0 (en) | 2004-08-17 | 2004-09-22 | Imp College Innovations Ltd | Cancer methods and medicaments |
| EP2460886B1 (en) * | 2005-05-04 | 2014-01-01 | University of South Florida | Predicting treatment response in cancer subjects |
| TWI428132B (zh) * | 2007-07-02 | 2014-03-01 | Lilly Co Eli | 癌症化療效果之強化 |
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2008
- 2008-06-18 TW TW097122720A patent/TWI428132B/zh not_active IP Right Cessation
- 2008-06-19 PE PE2008001054A patent/PE20090838A1/es not_active Application Discontinuation
- 2008-06-20 JP JP2010514996A patent/JP5551589B2/ja not_active Expired - Fee Related
- 2008-06-20 CN CN2012101150238A patent/CN102772416A/zh active Pending
- 2008-06-20 CL CL2008001848A patent/CL2008001848A1/es unknown
- 2008-06-20 MX MX2009013449A patent/MX2009013449A/es active IP Right Grant
- 2008-06-20 CN CN2008800231969A patent/CN101743005B/zh not_active Expired - Fee Related
- 2008-06-20 US US12/664,664 patent/US8318713B2/en not_active Expired - Fee Related
- 2008-06-20 WO PCT/US2008/067614 patent/WO2009006043A2/en not_active Ceased
- 2008-06-20 EA EA201201155A patent/EA023697B1/ru not_active IP Right Cessation
- 2008-06-20 AR ARP080102668A patent/AR067112A1/es unknown
- 2008-06-20 UA UAA200913938A patent/UA97400C2/uk unknown
- 2008-06-20 ES ES08771559.5T patent/ES2561202T3/es active Active
- 2008-06-20 AU AU2008270732A patent/AU2008270732B2/en not_active Ceased
- 2008-06-20 CA CA2691587A patent/CA2691587C/en not_active Expired - Fee Related
- 2008-06-20 NZ NZ581355A patent/NZ581355A/en not_active IP Right Cessation
- 2008-06-20 KR KR1020097027543A patent/KR101230085B1/ko not_active Expired - Fee Related
- 2008-06-20 BR BRPI0813789-7A2A patent/BRPI0813789A2/pt not_active IP Right Cessation
- 2008-06-20 MY MYPI20095640A patent/MY154472A/en unknown
- 2008-06-20 EA EA201070085A patent/EA018447B1/ru not_active IP Right Cessation
- 2008-06-20 EP EP08771559.5A patent/EP2173348B1/en active Active
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2009
- 2009-11-19 IL IL202237A patent/IL202237A/en not_active IP Right Cessation
- 2009-12-08 ZA ZA2009/08725A patent/ZA200908725B/en unknown
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2010
- 2010-01-27 MA MA32562A patent/MA31677B1/fr unknown
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2011
- 2011-12-02 CL CL2011003046A patent/CL2011003046A1/es unknown
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2012
- 2012-03-01 IL IL218443A patent/IL218443A0/en unknown
- 2012-10-18 US US13/654,884 patent/US8648063B2/en not_active Expired - Fee Related
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2014
- 2014-01-17 JP JP2014006560A patent/JP2014114297A/ja active Pending
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