EA021842B1 - Применение toll-подобного рецептора и агониста для лечения рака - Google Patents
Применение toll-подобного рецептора и агониста для лечения рака Download PDFInfo
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- EA021842B1 EA021842B1 EA201290140A EA201290140A EA021842B1 EA 021842 B1 EA021842 B1 EA 021842B1 EA 201290140 A EA201290140 A EA 201290140A EA 201290140 A EA201290140 A EA 201290140A EA 021842 B1 EA021842 B1 EA 021842B1
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Applications Claiming Priority (3)
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| US24925309P | 2009-10-06 | 2009-10-06 | |
| US24959609P | 2009-10-07 | 2009-10-07 | |
| PCT/US2010/051646 WO2011044246A1 (en) | 2009-10-06 | 2010-10-06 | Use of toll-like receptor and agonist for treating cancer |
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| EA201290140A1 EA201290140A1 (ru) | 2012-11-30 |
| EA021842B1 true EA021842B1 (ru) | 2015-09-30 |
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| EA201290140A EA021842B1 (ru) | 2009-10-06 | 2010-10-06 | Применение toll-подобного рецептора и агониста для лечения рака |
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| EP (1) | EP2486134B1 (enExample) |
| JP (2) | JP5796014B2 (enExample) |
| KR (1) | KR20120104177A (enExample) |
| CN (1) | CN104136614B (enExample) |
| AP (1) | AP2012006253A0 (enExample) |
| AU (1) | AU2010303464B2 (enExample) |
| BR (1) | BR112012011331B8 (enExample) |
| CA (1) | CA2777198C (enExample) |
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| IL (1) | IL219060A (enExample) |
| MX (1) | MX2012004095A (enExample) |
| MY (1) | MY163110A (enExample) |
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| ZA (1) | ZA201202500B (enExample) |
Families Citing this family (36)
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| WO2006069198A1 (en) | 2004-12-22 | 2006-06-29 | Cleveland Clinic Foundation | Flagellin related polypeptides and uses thereof |
| ES2412237T3 (es) | 2008-08-01 | 2013-07-10 | Cleveland Biolabs, Inc. | Métodos para tratar lesiones por reperfusión |
| SG191830A1 (en) | 2011-01-10 | 2013-08-30 | Cleveland Biolabs Inc | Use of toll-like receptor agonist for treating cancer |
| WO2014098649A1 (en) * | 2012-12-18 | 2014-06-26 | Obschestvo S Ogranichennoy Otvetstvennostyu "Panacela Labs" | Compositions and methods using toll-like receptor 5 and toll-like receptor agonist |
| WO2015080631A1 (en) * | 2013-11-27 | 2015-06-04 | Obschestvo S Ogranichennoy Otvetstvennost`Yu "Panacela Labs" | Improved expression vector for toll-like receptor and agonist and use for treating cancer |
| ES2816630T3 (es) * | 2014-07-30 | 2021-04-05 | Genome Prot Inc | Composiciones de flagelina y usos |
| JP6423889B2 (ja) | 2014-10-07 | 2018-11-14 | サイトリミック株式会社 | Ｈｓｐ７０由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法 |
| US10183056B2 (en) | 2014-10-16 | 2019-01-22 | Cleveland Biolabs, Inc. | Methods and compositions for the treatment of radiation-related disorders |
| EP3269733B1 (en) | 2015-03-09 | 2020-06-17 | Cytlimic Inc. | Peptide derived from gpc3, pharmaceutical composition for treatment or prevention of cancer using same, immunity inducer, and method for producing antigen-presenting cells |
| US10842848B2 (en) * | 2015-04-07 | 2020-11-24 | Cytlimic Inc. | Method for treating cancer by adminstering poly I:C and LAG-3-IgG fusion protein |
| KR101634380B1 (ko) | 2015-06-23 | 2016-06-28 | 한국생산기술연구원 | Tlr5 아고니스트 단백질의 생산방법 |
| CN105801709B (zh) * | 2016-04-29 | 2019-10-08 | 北京纽莱福生物科技有限公司 | CBLB502-Fc融合蛋白及其制备方法 |
| EP3527216B1 (en) | 2016-10-11 | 2024-02-14 | NEC Corporation | A medicine comprising a toll-like receptor agonist, lag-3 protein, a hsp70-derived peptide and a gpc3-derived peptide |
| RU2741228C2 (ru) * | 2016-11-14 | 2021-01-22 | Общество С Ограниченной Ответственностью "Панацела Лабс" | Противоопухолевые эффекты вирусного вектора, кодирующего толл-подобный рецептор и агонист толл-подобного рецептора |
| US11029609B2 (en) * | 2016-12-28 | 2021-06-08 | Asml Netherlands B.V. | Simulation-assisted alignment between metrology image and design |
| CN108853144A (zh) * | 2017-05-16 | 2018-11-23 | 科济生物医药（上海）有限公司 | Toll样受体激动剂与免疫效应细胞的联用 |
| EP3668529A4 (en) | 2017-07-20 | 2021-07-14 | Spogen Biotech Inc. | BIOACTIVE POLYPEPTIDES ALLOWING IMPROVEMENTS IN PROTECTION, GROWTH AND PRODUCTIVITY OF PLANTS |
| LT3768284T (lt) | 2018-03-19 | 2022-04-11 | 4D Pharma Research Limited | Enterecoccus flagelino kompozicijos, skirtos panaudoti terapijai |
| US12440536B2 (en) | 2018-05-18 | 2025-10-14 | The University Of Hong Kong | Compositions of toll-like receptor 5 (TLR5) agonist and methods of use thereof |
| WO2020163370A1 (en) | 2019-02-04 | 2020-08-13 | Codiak Biosciences, Inc. | Membrane protein scaffolds for exosome engineering |
| US12233356B2 (en) | 2019-03-21 | 2025-02-25 | Lonza Sales Ag | Process for preparing extracellular vesicles |
| US20240108747A1 (en) | 2019-03-21 | 2024-04-04 | Lonza Sales Ag | Extracellular vesicle conjugates and uses thereof |
| SG11202109702QA (en) | 2019-03-21 | 2021-10-28 | Codiak Biosciences Inc | Extracellular vesicles for vaccine delivery |
| WO2021003445A1 (en) | 2019-07-03 | 2021-01-07 | Codiak Biosciences, Inc. | Extracellular vesicles targeting t cells and uses thereof |
| US20230181758A1 (en) | 2019-07-03 | 2023-06-15 | Codiak Biosciences, Inc. | Extracellular vesicles targeting dendritic cells and uses thereof |
| EP4034081A1 (en) | 2019-09-25 | 2022-08-03 | Codiak BioSciences, Inc. | Extracellular vesicle compositions |
| EP4117717A1 (en) | 2020-03-13 | 2023-01-18 | Codiak BioSciences, Inc. | Extracellular vesicles for treating neurological disorders |
| EP4121450A2 (en) | 2020-03-20 | 2023-01-25 | Codiak BioSciences, Inc. | Extracellular vesicles for therapy |
| WO2021237100A1 (en) | 2020-05-21 | 2021-11-25 | Codiak Biosciences, Inc. | Methods of targeting extracellular vesicles to lung |
| KR102720967B1 (ko) * | 2020-06-04 | 2024-10-23 | 가톨릭대학교 산학협력단 | 플라젤린으로부터 유도된 tlr5 작용제를 유효성분으로 포함하는 면역관문억제제의 항암 효과 증진용 약학 조성물 |
| US20230220068A1 (en) | 2020-06-05 | 2023-07-13 | Codiak Biosciences, Inc. | Anti-transferrin extracellular vesicles |
| WO2022066928A2 (en) | 2020-09-23 | 2022-03-31 | Codiak Biosciences, Inc. | Process for preparing extracellular vesicles |
| EP4216993A2 (en) | 2020-09-23 | 2023-08-02 | Codiak BioSciences, Inc. | Methods of producing extracellular vesicles |
| WO2022066883A1 (en) | 2020-09-23 | 2022-03-31 | Codiak Biosciences, Inc. | Extracellular vesicles comprising kras antigens and uses thereof |
| EP4620482A1 (en) * | 2024-03-18 | 2025-09-24 | Istituto Europeo di Oncologia S.r.l. | Flagellin-related peptides and uses thereof |
| WO2025196053A1 (en) * | 2024-03-18 | 2025-09-25 | Istituto Europeo Di Oncologia S.R.L. | Flagellin-related peptides and uses thereof |
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| US20050147627A1 (en) * | 2001-04-20 | 2005-07-07 | The Institute For Systems Biology | Toll-like receptor 5 ligands and methods of use |
| US20080063657A1 (en) * | 2005-01-19 | 2008-03-13 | Powell Thomas J | Compositions comprising pathogen-associated molecular patterns and antigens and methods of use thereof |
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| US20090246303A1 (en) * | 2003-12-02 | 2009-10-01 | Gudkov Andrei V | Method for Reducing The Effects of Chemotherapy Using Flagellin Related Polypeptides |
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- 2010-10-06 JP JP2012533282A patent/JP5796014B2/ja not_active Expired - Fee Related
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- 2010-10-06 AP AP2012006253A patent/AP2012006253A0/xx unknown
- 2010-10-06 KR KR1020127008759A patent/KR20120104177A/ko not_active Ceased
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- 2010-10-06 US US13/500,552 patent/US9205095B2/en active Active
- 2010-10-06 CN CN201080055226.1A patent/CN104136614B/zh not_active Expired - Fee Related
- 2010-10-06 EA EA201290140A patent/EA021842B1/ru unknown
- 2010-10-06 ES ES10822611.9T patent/ES2457518T3/es active Active
- 2010-10-06 MX MX2012004095A patent/MX2012004095A/es active IP Right Grant
- 2010-10-06 WO PCT/US2010/051646 patent/WO2011044246A1/en not_active Ceased
- 2010-10-06 BR BR112012011331A patent/BR112012011331B8/pt not_active IP Right Cessation
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2012
- 2012-04-04 IL IL219060A patent/IL219060A/en active IP Right Grant
- 2012-04-05 ZA ZA2012/02500A patent/ZA201202500B/en unknown
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- 2015-06-26 JP JP2015128384A patent/JP2015165821A/ja active Pending
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| US20050147627A1 (en) * | 2001-04-20 | 2005-07-07 | The Institute For Systems Biology | Toll-like receptor 5 ligands and methods of use |
| US20090246303A1 (en) * | 2003-12-02 | 2009-10-01 | Gudkov Andrei V | Method for Reducing The Effects of Chemotherapy Using Flagellin Related Polypeptides |
| US20090011982A1 (en) * | 2004-12-22 | 2009-01-08 | Gudkov Andrei V | Flagellin Related Polypeptides and Uses Thereof |
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Also Published As
| Publication number | Publication date |
|---|---|
| BR112012011331B8 (pt) | 2021-05-25 |
| BR112012011331A2 (pt) | 2015-09-15 |
| KR20120104177A (ko) | 2012-09-20 |
| EA201290140A1 (ru) | 2012-11-30 |
| ZA201202500B (en) | 2013-06-26 |
| AP2012006253A0 (en) | 2012-06-30 |
| BR112012011331B1 (pt) | 2021-03-02 |
| AU2010303464B2 (en) | 2014-05-01 |
| IL219060A0 (en) | 2012-06-28 |
| AU2010303464A1 (en) | 2012-04-12 |
| ES2457518T3 (es) | 2014-04-28 |
| WO2011044246A1 (en) | 2011-04-14 |
| JP2013506437A (ja) | 2013-02-28 |
| EP2486134A4 (en) | 2013-02-13 |
| HK1199058A1 (en) | 2015-06-19 |
| CA2777198C (en) | 2018-07-24 |
| JP2015165821A (ja) | 2015-09-24 |
| CN104136614A (zh) | 2014-11-05 |
| CN104136614B (zh) | 2018-04-06 |
| US9205095B2 (en) | 2015-12-08 |
| MX2012004095A (es) | 2012-09-12 |
| US20120208871A1 (en) | 2012-08-16 |
| EP2486134B1 (en) | 2014-01-08 |
| IL219060A (en) | 2017-02-28 |
| MY163110A (en) | 2017-08-15 |
| JP5796014B2 (ja) | 2015-10-21 |
| EP2486134A1 (en) | 2012-08-15 |
| CA2777198A1 (en) | 2011-04-14 |
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