AU2010303464B2 - Use of toll-like receptor and agonist for treating cancer - Google Patents

Use of toll-like receptor and agonist for treating cancer Download PDF

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Publication number
AU2010303464B2
AU2010303464B2 AU2010303464A AU2010303464A AU2010303464B2 AU 2010303464 B2 AU2010303464 B2 AU 2010303464B2 AU 2010303464 A AU2010303464 A AU 2010303464A AU 2010303464 A AU2010303464 A AU 2010303464A AU 2010303464 B2 AU2010303464 B2 AU 2010303464B2
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Australia
Prior art keywords
vector
agent
flagellin
tlr
tumor
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AU2010303464A
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AU2010303464A1 (en
Inventor
Andrei V. Gudkov
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Panacela Labs LLC
Park Roswell Cancer Institute
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Panacela Labs LLC
Park Roswell Cancer Institute
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Assigned to ROSWELL PARK CANCER INSTITUTE, PANACELA LABS LLC reassignment ROSWELL PARK CANCER INSTITUTE Request for Assignment Assignors: PANACELA LABS, INC., ROSWELL PARK CANCER INSTITUTE
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K38/18—Growth factors; Growth regulators
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/22—Hormones
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2799/00—Uses of viruses
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/20—Vector systems having a special element relevant for transcription transcription of more than one cistron

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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AU2010303464A 2009-10-06 2010-10-06 Use of toll-like receptor and agonist for treating cancer Ceased AU2010303464B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24925309P 2009-10-06 2009-10-06
US61/249,253 2009-10-06
US24959609P 2009-10-07 2009-10-07
US61/249,596 2009-10-07
PCT/US2010/051646 WO2011044246A1 (en) 2009-10-06 2010-10-06 Use of toll-like receptor and agonist for treating cancer

Publications (2)

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AU2010303464A1 AU2010303464A1 (en) 2012-04-12
AU2010303464B2 true AU2010303464B2 (en) 2014-05-01

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AU2010303464A Ceased AU2010303464B2 (en) 2009-10-06 2010-10-06 Use of toll-like receptor and agonist for treating cancer

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US (1) US9205095B2 (enExample)
EP (1) EP2486134B1 (enExample)
JP (2) JP5796014B2 (enExample)
KR (1) KR20120104177A (enExample)
CN (1) CN104136614B (enExample)
AP (1) AP2012006253A0 (enExample)
AU (1) AU2010303464B2 (enExample)
BR (1) BR112012011331B8 (enExample)
CA (1) CA2777198C (enExample)
EA (1) EA021842B1 (enExample)
ES (1) ES2457518T3 (enExample)
IL (1) IL219060A (enExample)
MX (1) MX2012004095A (enExample)
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ZA (1) ZA201202500B (enExample)

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BR112012011331B8 (pt) 2021-05-25
BR112012011331A2 (pt) 2015-09-15
KR20120104177A (ko) 2012-09-20
EA201290140A1 (ru) 2012-11-30
ZA201202500B (en) 2013-06-26
AP2012006253A0 (en) 2012-06-30
BR112012011331B1 (pt) 2021-03-02
IL219060A0 (en) 2012-06-28
AU2010303464A1 (en) 2012-04-12
ES2457518T3 (es) 2014-04-28
WO2011044246A1 (en) 2011-04-14
JP2013506437A (ja) 2013-02-28
EP2486134A4 (en) 2013-02-13
HK1199058A1 (en) 2015-06-19
CA2777198C (en) 2018-07-24
JP2015165821A (ja) 2015-09-24
CN104136614A (zh) 2014-11-05
CN104136614B (zh) 2018-04-06
US9205095B2 (en) 2015-12-08
MX2012004095A (es) 2012-09-12
US20120208871A1 (en) 2012-08-16
EP2486134B1 (en) 2014-01-08
EA021842B1 (ru) 2015-09-30
IL219060A (en) 2017-02-28
MY163110A (en) 2017-08-15
JP5796014B2 (ja) 2015-10-21
EP2486134A1 (en) 2012-08-15
CA2777198A1 (en) 2011-04-14

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