EA020923B1 - Производные димерного 1-арилпиразола - Google Patents

Производные димерного 1-арилпиразола Download PDF

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Publication number
EA020923B1
EA020923B1 EA201100800A EA201100800A EA020923B1 EA 020923 B1 EA020923 B1 EA 020923B1 EA 201100800 A EA201100800 A EA 201100800A EA 201100800 A EA201100800 A EA 201100800A EA 020923 B1 EA020923 B1 EA 020923B1
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EA
Eurasian Patent Office
Prior art keywords
composition
compounds
independently represent
group
compound
Prior art date
Application number
EA201100800A
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English (en)
Russian (ru)
Other versions
EA201100800A1 (ru
Inventor
Чарльз К. Менг
Original Assignee
Мериал Лимитед
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Application filed by Мериал Лимитед filed Critical Мериал Лимитед
Publication of EA201100800A1 publication Critical patent/EA201100800A1/ru
Publication of EA020923B1 publication Critical patent/EA020923B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
EA201100800A 2008-11-19 2009-11-18 Производные димерного 1-арилпиразола EA020923B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11602108P 2008-11-19 2008-11-19
PCT/US2009/064981 WO2010059719A2 (en) 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives

Publications (2)

Publication Number Publication Date
EA201100800A1 EA201100800A1 (ru) 2011-12-30
EA020923B1 true EA020923B1 (ru) 2015-02-27

Family

ID=42034586

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201100800A EA020923B1 (ru) 2008-11-19 2009-11-18 Производные димерного 1-арилпиразола

Country Status (12)

Country Link
US (1) US8642636B2 (enExample)
EP (1) EP2364300B1 (enExample)
JP (1) JP2012509338A (enExample)
CN (1) CN102264706A (enExample)
AU (1) AU2009316710B2 (enExample)
BR (1) BRPI0922042B1 (enExample)
CA (2) CA2743553C (enExample)
EA (1) EA020923B1 (enExample)
ES (1) ES2605811T3 (enExample)
MX (1) MX2011005214A (enExample)
NZ (1) NZ592985A (enExample)
WO (1) WO2010059719A2 (enExample)

Families Citing this family (23)

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SI2712358T1 (sl) 2011-05-13 2017-03-31 Array Biopharma, Inc. Spojine pirolidinil sečnine, pirolidinil tiosečnine in pirolidinil gvanidina kot inhibitorji kinaze trka
WO2014078328A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-bicyclic aryl,n'-pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9828360B2 (en) 2012-11-13 2017-11-28 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
RU2664541C2 (ru) 2012-11-13 2018-08-20 Эррэй Биофарма Инк. Бициклические соединения мочевины, тиомочевины, гуанидина и цианогуанидина, пригодные для лечения боли
US9790178B2 (en) 2012-11-13 2017-10-17 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
ES2664331T3 (es) 2012-11-13 2018-04-19 Array Biopharma, Inc. Compuestos de N-pirrolidinilo, N'-pirazolilurea, tiourea, guanidina y cianoguanidina como inhibidores de la cinasa Trka
WO2014078325A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-(monocyclic aryl),n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078408A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078322A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078331A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-(arylalkyl)-n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9809578B2 (en) 2012-11-13 2017-11-07 Array Biopharma Inc. Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors
JP2016164125A (ja) * 2013-07-02 2016-09-08 国立大学法人帯広畜産大学 バベシア症の治療剤及び予防剤
PT3154959T (pt) 2014-05-15 2019-09-24 Array Biopharma Inc 1-((3s,4r)-4-(3-fluorofenil)-1-(2-metoxietil)-pirrolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)ureia como inibidor da cinase trka
WO2017195173A1 (en) 2016-05-12 2017-11-16 Verdesian Life Sciences, U.S., Llc Compositions for controlling enzyme-induced urea decomposition
US11261136B2 (en) 2017-03-28 2022-03-01 Verdesian Life Sciences U.S., Llc Triarylmethane compounds for controlling enzyme-induced urea decomposition
AU2019376614B2 (en) 2018-11-06 2025-12-04 Corteva Agriscience Llc Safened compositions comprising pyridine carboxylate herbicides and cloquintocet
PL3876726T3 (pl) * 2018-11-06 2025-04-07 Corteva Agriscience Llc Kompozycje zawierające środki chwastobójcze na bazie pirydynokarboksylanu i środki zabezpieczające na bazie karboksylanu azolu
ES3041637T3 (en) 2018-11-07 2025-11-13 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides and 4-hydroxyphenyl-pyruvate dioxygenase (hppd) inhibitor herbicides
EP3876733B1 (en) 2018-11-07 2025-07-02 Corteva Agriscience LLC Compositions comprising pyridine carboxylate herbicides with photosystem ii and optional hppd inhibitor herbicides
CA3118677A1 (en) 2018-11-07 2020-05-14 Corteva Agriscience Llc Compositions comprising a pyridine carboxylate herbicide and protoporphyrinogen oxidase (protox) inhibitor herbicides
JP7449931B2 (ja) 2018-11-07 2024-03-14 コルテバ アグリサイエンス エルエルシー アセト乳酸合成酵素（ａｌｓ）阻害剤除草剤と共にピリジンカルボキシレート除草剤を含む組成物
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
JP7724845B2 (ja) 2020-07-24 2025-08-18 エランコ・ユーエス・インコーポレイテッド イソオキサゾリン化合物及びその中間体を作製するための方法

Citations (2)

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Publication number Priority date Publication date Assignee Title
US3966900A (en) * 1969-03-12 1976-06-29 Airwick Industries, Inc. Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
US20070275976A1 (en) * 2004-06-26 2007-11-29 Stefan Schnatterer N-phenylpyrazole derivatives as pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1402713A (zh) * 1999-12-02 2003-03-12 阿温提斯作物科学股份有限公司 控制动物中的节肢动物
US7262214B2 (en) * 2003-02-26 2007-08-28 Merial Limited 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966900A (en) * 1969-03-12 1976-06-29 Airwick Industries, Inc. Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
US20070275976A1 (en) * 2004-06-26 2007-11-29 Stefan Schnatterer N-phenylpyrazole derivatives as pesticides

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BOURGUIGNON J.: "IDENTICAL AND NONIDENTICAL TWIN DRUGS". PRACTICE OF MEDICINAL CHEMISTRY, 1 January 1996 (1996-01-01), pages 261-293, XP001248799, the whole document *
DATABASE BEILSTEIN 1996, XP002575606. Database accession no. 6036932, abstract & COUR, AGNETE LA; FINDEISEN, MATTHIAS; HAZELL, RITA; HENNIG, LOTHAR; OLSEN, CARL ERIK; SIMONSEN, OLE: J. CHEM. SOC., DALTON TRANSACTIONS: INORGANIC CHEMISTRY, vol. 16, 1996, pages 3437-3448 *
DATABASE BEILSTEIN. BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; 1959, XP002575607. Database accession no. 630245, abstract & FINAR; LORD: J. CHEM. SOC., 1959, pages 1819-1821 *
DATABASE BEILSTEIN. BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; 1996, XP002575604. Database accession no. 6010790, abstract & NIVOROZHKIN, ALEXANDER L.; TOFTLUND, HANS; JOERGENSEN, PER LAUGE; NIVOROZHKIN, LEONID E.: J. CHEM. SOC., DALTON TRANSACTIONS: INORG. CHEM., vol. 7, 1996, pages 1215-1222 *
DATABASE BEILSTEIN. BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; 1997, XP002575605. Database accession no. 6206504, abstract & AHLUWALIA, V. K.; SHARMA, POOJA; GOYAL, BINDU: IND. J. CHEM., SECTION B: ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, vol. 36, 1997, pages 1059-1061 *

Also Published As

Publication number Publication date
BRPI0922042B1 (pt) 2020-01-28
US8642636B2 (en) 2014-02-04
EP2364300B1 (en) 2016-10-19
CA2952443A1 (en) 2010-05-27
CA2952443C (en) 2019-04-02
BRPI0922042A2 (pt) 2016-11-01
WO2010059719A3 (en) 2010-11-18
JP2012509338A (ja) 2012-04-19
CA2743553C (en) 2017-03-14
EP2364300A2 (en) 2011-09-14
CN102264706A (zh) 2011-11-30
AU2009316710B2 (en) 2015-08-06
AU2009316710A1 (en) 2010-05-27
CA2743553A1 (en) 2010-05-27
ES2605811T3 (es) 2017-03-16
NZ592985A (en) 2013-04-26
WO2010059719A2 (en) 2010-05-27
US20110245157A1 (en) 2011-10-06
EA201100800A1 (ru) 2011-12-30
MX2011005214A (es) 2011-06-01
HK1160852A1 (en) 2012-08-17

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU