BRPI0922042B1 - derivados de 1-arilpirazol diméricos - Google Patents

derivados de 1-arilpirazol diméricos Download PDF

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Publication number
BRPI0922042B1
BRPI0922042B1 BRPI0922042A BRPI0922042A BRPI0922042B1 BR PI0922042 B1 BRPI0922042 B1 BR PI0922042B1 BR PI0922042 A BRPI0922042 A BR PI0922042A BR PI0922042 A BRPI0922042 A BR PI0922042A BR PI0922042 B1 BRPI0922042 B1 BR PI0922042B1
Authority
BR
Brazil
Prior art keywords
group
alkyl
spp
independently selected
compound
Prior art date
Application number
BRPI0922042A
Other languages
English (en)
Portuguese (pt)
Inventor
Q Meng Charles
Original Assignee
Merial Ltd
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, Merial Inc filed Critical Merial Ltd
Publication of BRPI0922042A2 publication Critical patent/BRPI0922042A2/pt
Publication of BRPI0922042B1 publication Critical patent/BRPI0922042B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0922042A 2008-11-19 2009-11-18 derivados de 1-arilpirazol diméricos BRPI0922042B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11602108P 2008-11-19 2008-11-19
PCT/US2009/064981 WO2010059719A2 (en) 2008-11-19 2009-11-18 Dimeric 1-arylpyrazole derivatives

Publications (2)

Publication Number Publication Date
BRPI0922042A2 BRPI0922042A2 (pt) 2016-11-01
BRPI0922042B1 true BRPI0922042B1 (pt) 2020-01-28

Family

ID=42034586

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922042A BRPI0922042B1 (pt) 2008-11-19 2009-11-18 derivados de 1-arilpirazol diméricos

Country Status (12)

Country Link
US (1) US8642636B2 (enExample)
EP (1) EP2364300B1 (enExample)
JP (1) JP2012509338A (enExample)
CN (1) CN102264706A (enExample)
AU (1) AU2009316710B2 (enExample)
BR (1) BRPI0922042B1 (enExample)
CA (2) CA2743553C (enExample)
EA (1) EA020923B1 (enExample)
ES (1) ES2605811T3 (enExample)
MX (1) MX2011005214A (enExample)
NZ (1) NZ592985A (enExample)
WO (1) WO2010059719A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102001364B1 (ko) 2011-05-13 2019-07-22 어레이 바이오파마 인크. Trka 키나제 저해제로서의 피롤리디닐 유레아 및 피롤리디닐 티오유레아 화합물
US9828360B2 (en) 2012-11-13 2017-11-28 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
US9896435B2 (en) 2012-11-13 2018-02-20 Array Biopharma Inc. N-pyrrolidinyl,N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
WO2014078322A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9822118B2 (en) 2012-11-13 2017-11-21 Array Biopharma Inc. Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
US9809578B2 (en) 2012-11-13 2017-11-07 Array Biopharma Inc. Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors
WO2014078328A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-bicyclic aryl,n'-pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078372A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
WO2014078325A1 (en) 2012-11-13 2014-05-22 Array Biopharma Inc. N-(monocyclic aryl),n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
US9969694B2 (en) 2012-11-13 2018-05-15 Array Biopharma Inc. N-(arylalkyl)-N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
ME02879B (me) 2012-11-13 2018-04-20 Array Biopharma Inc Jedinjenja biciklične uree, tiouree, guanidina i cijanoguanidina korisna za lečenje bola
JP2016164125A (ja) * 2013-07-02 2016-09-08 国立大学法人帯広畜産大学 バベシア症の治療剤及び予防剤
HRP20191593T1 (hr) 2014-05-15 2019-11-29 Array Biopharma Inc 1-((3s,4r)-4-(3-fluorfenil)-1-(2-metoksietil)pirolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)urea kao inhibitor trka kinaze
US11384032B2 (en) 2016-05-12 2022-07-12 Verdesian Life Sciences, U.S., Llc Compositions for controlling enzyme-induced urea decomposition
CA3058394A1 (en) 2017-03-28 2018-10-04 Verdesian Life Sciences U.S., Llc Triarylmethane compounds for controlling enzyme-induced urea decomposition
CN113453551B (zh) * 2018-11-06 2023-10-13 科迪华农业科技有限责任公司 包含羧酸吡啶除草剂和羧酸唑安全剂的组合物
CA3119026A1 (en) 2018-11-06 2020-05-14 Corteva Agriscience Llc Safened compositions comprising pyridine carboxylate herbicides and cloquintocet
ES3037961T3 (en) 2018-11-07 2025-10-08 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides with acetolactate synthase (als) inhibitor herbicides
CA3118565A1 (en) 2018-11-07 2020-05-14 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides with photosystem ii and optional hppd inhibitor herbicides
PL3876729T3 (pl) 2018-11-07 2025-04-14 Corteva Agriscience Llc Kompozycje zawierające herbicyd pirydynokarboksylanowy oraz herbicydy będące inhibitorami oksydazy protoporfirynogenu (protox)
US12453349B2 (en) 2018-11-07 2025-10-28 Corteva Agriscience Llc Compositions comprising pyridine carboxylate herbicides and 4-hydroxyphenyl-pyruvate dioxygenase (HPPD) inhibitor herbicides
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
EP4185585A1 (en) 2020-07-24 2023-05-31 Elanco Us Inc. Process for making an isoxazoline compound and intermediate thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966900A (en) * 1969-03-12 1976-06-29 Airwick Industries, Inc. Evaporator system comprising a stabilized pesticidal phosphoric acid ester and method for stabilizing such ester enclosed in an evaporator
EP1237873B1 (en) * 1999-12-02 2013-04-03 Merial Limited Control of arthropods in animals
US7262214B2 (en) * 2003-02-26 2007-08-28 Merial Limited 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases
WO2006000313A1 (en) * 2004-06-26 2006-01-05 Merial Ltd. N-phenylpyrazole derivatives as pesticides

Also Published As

Publication number Publication date
MX2011005214A (es) 2011-06-01
EA020923B1 (ru) 2015-02-27
US20110245157A1 (en) 2011-10-06
EP2364300A2 (en) 2011-09-14
ES2605811T3 (es) 2017-03-16
CA2952443A1 (en) 2010-05-27
CA2743553C (en) 2017-03-14
AU2009316710B2 (en) 2015-08-06
US8642636B2 (en) 2014-02-04
JP2012509338A (ja) 2012-04-19
CN102264706A (zh) 2011-11-30
NZ592985A (en) 2013-04-26
BRPI0922042A2 (pt) 2016-11-01
HK1160852A1 (en) 2012-08-17
WO2010059719A3 (en) 2010-11-18
WO2010059719A2 (en) 2010-05-27
EA201100800A1 (ru) 2011-12-30
AU2009316710A1 (en) 2010-05-27
CA2952443C (en) 2019-04-02
EP2364300B1 (en) 2016-10-19
CA2743553A1 (en) 2010-05-27

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Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority

Free format text: OBSERVA-SE QUE A PRIORIDADE REQUERIDA US 61/116,021 DE 19.11.2008 POSSUI DEPOSITANTE DIFERENTE DO INFORMADO NA ENTRADA NA FASE NACIONAL E SUA RESPECTIVA CESSAO FOI APRESENTADA EM 19/11/2012 APOS O PRAZO REGULAR DE 60 DIAS DA ENTRADA NA FASE NACIONAL QUE SE ENCERRAVA EM 18/07/2011, MOTIVO PELO QUAL SERA DADA PERDA DESTA PRIORIDADE, CONFORME AS DISPOSICOES PREVISTAS NA LEI 9.279 DE 14/05/1996 (LPI) ART. 16 7O.

B25A Requested transfer of rights approved

Owner name: MERIAL, INC. (US)

B12F Other appeals [chapter 12.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 28/01/2020, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC. (US)