EA018536B1 - Фармацевтический препарат, содержащий толперизон - Google Patents

Фармацевтический препарат, содержащий толперизон Download PDF

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Publication number
EA018536B1
EA018536B1 EA201070747A EA201070747A EA018536B1 EA 018536 B1 EA018536 B1 EA 018536B1 EA 201070747 A EA201070747 A EA 201070747A EA 201070747 A EA201070747 A EA 201070747A EA 018536 B1 EA018536 B1 EA 018536B1
Authority
EA
Eurasian Patent Office
Prior art keywords
tolperisone
preparation according
pharmaceutical preparation
acid
pharmaceutical
Prior art date
Application number
EA201070747A
Other languages
English (en)
Russian (ru)
Other versions
EA201070747A1 (ru
Inventor
Оттилиа Балаж
Карой Тиханьи
Каталин Хорнок
Иштванне Киш-Варга
Мария Вираг-Хадаш
Original Assignee
Рихтер Гедеон Нирт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рихтер Гедеон Нирт. filed Critical Рихтер Гедеон Нирт.
Publication of EA201070747A1 publication Critical patent/EA201070747A1/ru
Publication of EA018536B1 publication Critical patent/EA018536B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201070747A 2007-12-20 2008-12-18 Фармацевтический препарат, содержащий толперизон EA018536B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0700828A HUP0700828A2 (en) 2007-12-20 2007-12-20 Transdermal pharmaceutical compositions containing tolperisone alone and in combination
PCT/HU2008/000153 WO2009081217A1 (en) 2007-12-20 2008-12-18 Pharmaceutical formulations containing tolperisone

Publications (2)

Publication Number Publication Date
EA201070747A1 EA201070747A1 (ru) 2010-12-30
EA018536B1 true EA018536B1 (ru) 2013-08-30

Family

ID=89987953

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070747A EA018536B1 (ru) 2007-12-20 2008-12-18 Фармацевтический препарат, содержащий толперизон

Country Status (7)

Country Link
US (1) US20100273746A1 (enExample)
EP (1) EP2231116A1 (enExample)
JP (1) JP2011507826A (enExample)
CA (1) CA2709538A1 (enExample)
EA (1) EA018536B1 (enExample)
HU (1) HUP0700828A2 (enExample)
WO (1) WO2009081217A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2711624C2 (ru) * 2017-06-30 2020-01-17 Общество с ограниченной ответственностью "ФБК" Комбинированное средство на основе нпвс, миорелаксанта и витамина

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011002688A (es) * 2008-09-12 2011-04-12 Critical Pharmaceuticals Ltd Mejoramientos en la absorcion de agentes terapeuticos a traves de las membranas mucosas o la piel.
JP5739679B2 (ja) * 2010-03-01 2015-06-24 ロート製薬株式会社 外用組成物
PT2704703T (pt) * 2011-05-03 2019-10-25 Aponia Laboratories Inc Composições transdermais de ibuprofeno e seus métodos de utilização.
WO2012172413A1 (en) 2011-06-16 2012-12-20 Abbott Healthcare Pvt. Ltd. Pharmaceutical composition comprising a combination of eperisone and diclofenac and process for preparing thereof
KR101156054B1 (ko) * 2011-09-05 2012-06-20 주식회사 네비팜 안정한 에페리손 함유 서방성 의약조성물
UA119324C2 (uk) * 2013-04-02 2019-06-10 Теміс Медікер Лімітед Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні
BR112017016010B1 (pt) * 2015-01-30 2023-02-14 Medrx Co., Ltd Preparação aquosa para uso externo.
TR201720293A2 (tr) * 2017-12-13 2019-06-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Tolperi̇zon ve non-selekti̇f cox i̇nhi̇bi̇törü kombi̇nasyonlari
WO2020086046A2 (en) * 2018-10-26 2020-04-30 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Topical compositions comprising tolperisone and flurbiprofen combination
MX2022005168A (es) 2019-11-06 2022-06-08 Smartech Topical Inc Formulaciones topicas de inhibidores de la ciclooxigenasa y su uso.
AU2022271274A1 (en) * 2021-05-05 2023-11-23 Smartech Topical, Inc. Topical naproxen formulations and their use
CN114939104B (zh) * 2022-06-02 2023-10-24 杭州润宠归美生物科技有限公司 一种用于减轻猫应激的外用透皮制剂、制备方法及应用
CN116966136A (zh) * 2023-08-01 2023-10-31 上海瑞凝生物科技有限公司 一种磁性可载药封堵水凝胶及其制备方法和应用
CN120919084A (zh) * 2025-08-27 2025-11-11 广州神元辉康生物医药科技有限公司 一种药物组合物及其制备方法和用途

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0295411A1 (en) * 1987-05-15 1988-12-21 Sansho Co., Ltd. Pharmaceutical preparation for percutaneous administration containing eperisone or tolperisone or a salt thereof
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
JPH0640917A (ja) * 1991-06-21 1994-02-15 Nichiban Co Ltd トルペリゾン又はエペリゾン含有ハップ剤
JP2000143510A (ja) * 1998-11-16 2000-05-23 Taisho Pharmaceut Co Ltd 外用組成物
WO2005032514A1 (en) * 2003-10-09 2005-04-14 Richter Gedeon Vegyészeti Gyár Rt. Transdermal pharmaceutical composition

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6087215A (ja) * 1983-10-19 1985-05-16 Mitsui Toatsu Chem Inc 外用薬用基材
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5252588A (en) * 1990-04-27 1993-10-12 Sekisui Kagaku Kogyo Kabushiki Kaisha Percutaneously absorbable crosslinked polyvinylpyrrolidone eperisone or tolperisone preparation
JP3525225B2 (ja) * 1992-11-09 2004-05-10 積水化学工業株式会社 エペリゾンまたはトルペリゾン経皮吸収テープ剤またはパッチ剤、およびその製造方法
IT1265001B1 (it) * 1993-12-16 1996-10-17 Zambon Spa Composizione farmaceutica per uso topico contenente acido (s)-2-(4- isobutilfenil) propionico
JP3483148B2 (ja) * 1994-04-21 2004-01-06 久光製薬株式会社 経皮投与基剤組成物およびその薬剤組成物
US5846620A (en) * 1997-02-06 1998-12-08 W. R. Grace & Co.-Conn. High strength flexible film package
US20020004065A1 (en) * 2000-01-20 2002-01-10 David Kanios Compositions and methods to effect the release profile in the transdermal administration of active agents
US20050163831A1 (en) * 2002-08-02 2005-07-28 Hisamitsu Pharmaceutical Co., Inc. Patch for transdermal administration
US8034374B2 (en) * 2003-03-18 2011-10-11 Hisamitsu Pharmaceutical Co., Inc. Patch containing nonsteroidal anti-inflammatory and analgesic agent
EP1644004A4 (en) * 2003-06-20 2010-10-06 Ronald Aung-Din LOCAL THERAPY FOR THE TREATMENT OF MIGRAINS, MUSCLE CLARIFICATIONS, MUSCLE SPASMS, SPASTICITY AND RELATED CONDITIONS
AT500144A1 (de) * 2004-03-05 2005-11-15 Sanochemia Pharmazeutika Ag Tolperison enthaltende, pharmazeutische zubereitung mit steuerbarer wirkstofffreisetzung zur oralen verabreichung
WO2005102334A2 (en) * 2004-04-13 2005-11-03 Alza Corporation Apparatus and method for transdermal delivery of fentany-based agents
CA2570599C (en) * 2004-06-24 2012-03-27 Idexx Laboratories, Inc. Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
US20060004050A1 (en) * 2004-07-02 2006-01-05 Speicher Brian T Compositions and methods for the prevention or treatment of pain and other nervous system disorders
JP4782800B2 (ja) * 2004-12-17 2011-09-28 エクソンモービル・ケミカル・パテンツ・インク 均一ポリマー・ブレンドおよび該ブレンドからの製品
AT505225A1 (de) * 2007-04-26 2008-11-15 Sanochemia Pharmazeutika Ag 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0295411A1 (en) * 1987-05-15 1988-12-21 Sansho Co., Ltd. Pharmaceutical preparation for percutaneous administration containing eperisone or tolperisone or a salt thereof
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
JPH0640917A (ja) * 1991-06-21 1994-02-15 Nichiban Co Ltd トルペリゾン又はエペリゾン含有ハップ剤
JP2000143510A (ja) * 1998-11-16 2000-05-23 Taisho Pharmaceut Co Ltd 外用組成物
WO2005032514A1 (en) * 2003-10-09 2005-04-14 Richter Gedeon Vegyészeti Gyár Rt. Transdermal pharmaceutical composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200429 Thomson Scientific, London, GB; AN 2004-312695 XP002522007 & RO 118177 В (EUROPHARMACEUTICALS SA) 28 March 2003 (2003-03-28) abstract *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2711624C2 (ru) * 2017-06-30 2020-01-17 Общество с ограниченной ответственностью "ФБК" Комбинированное средство на основе нпвс, миорелаксанта и витамина

Also Published As

Publication number Publication date
WO2009081217A1 (en) 2009-07-02
EP2231116A1 (en) 2010-09-29
US20100273746A1 (en) 2010-10-28
HUP0700828A2 (en) 2010-01-28
CA2709538A1 (en) 2009-07-02
EA201070747A1 (ru) 2010-12-30
JP2011507826A (ja) 2011-03-10
HU0700828D0 (en) 2008-02-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU