JP2011507826A - トルペリゾンを含む医薬製剤 - Google Patents

トルペリゾンを含む医薬製剤 Download PDF

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Publication number
JP2011507826A
JP2011507826A JP2010538924A JP2010538924A JP2011507826A JP 2011507826 A JP2011507826 A JP 2011507826A JP 2010538924 A JP2010538924 A JP 2010538924A JP 2010538924 A JP2010538924 A JP 2010538924A JP 2011507826 A JP2011507826 A JP 2011507826A
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JP
Japan
Prior art keywords
tolperisone
pharmaceutical formulation
acid
gel
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010538924A
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English (en)
Japanese (ja)
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JP2011507826A5 (enExample
Inventor
オッティリア・バラージュ
カロリー・ティハンイ
カタリン・ホルノク
イシュトヴァーンネー・キス−ヴァルガ
マーリア・ヴィラーグ−ハダス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Nyrt
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of JP2011507826A publication Critical patent/JP2011507826A/ja
Publication of JP2011507826A5 publication Critical patent/JP2011507826A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010538924A 2007-12-20 2008-12-18 トルペリゾンを含む医薬製剤 Pending JP2011507826A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0700828A HUP0700828A2 (en) 2007-12-20 2007-12-20 Transdermal pharmaceutical compositions containing tolperisone alone and in combination
PCT/HU2008/000153 WO2009081217A1 (en) 2007-12-20 2008-12-18 Pharmaceutical formulations containing tolperisone

Publications (2)

Publication Number Publication Date
JP2011507826A true JP2011507826A (ja) 2011-03-10
JP2011507826A5 JP2011507826A5 (enExample) 2011-07-14

Family

ID=89987953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010538924A Pending JP2011507826A (ja) 2007-12-20 2008-12-18 トルペリゾンを含む医薬製剤

Country Status (7)

Country Link
US (1) US20100273746A1 (enExample)
EP (1) EP2231116A1 (enExample)
JP (1) JP2011507826A (enExample)
CA (1) CA2709538A1 (enExample)
EA (1) EA018536B1 (enExample)
HU (1) HUP0700828A2 (enExample)
WO (1) WO2009081217A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2519193C2 (ru) * 2008-09-12 2014-06-10 Критикал Фармасьютикалс Лимитед Усовершенствование всасывания терапевтических средств через слизистые оболочки или кожу
JP5739679B2 (ja) * 2010-03-01 2015-06-24 ロート製薬株式会社 外用組成物
EA026697B1 (ru) 2011-05-03 2017-05-31 Апониа Лабораториз, Инк. Трансдермальные композиции ибупрофена и способы их применения
WO2012172413A1 (en) 2011-06-16 2012-12-20 Abbott Healthcare Pvt. Ltd. Pharmaceutical composition comprising a combination of eperisone and diclofenac and process for preparing thereof
KR101156054B1 (ko) * 2011-09-05 2012-06-20 주식회사 네비팜 안정한 에페리손 함유 서방성 의약조성물
UA119324C2 (uk) * 2013-04-02 2019-06-10 Теміс Медікер Лімітед Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні
BR112017016010B1 (pt) * 2015-01-30 2023-02-14 Medrx Co., Ltd Preparação aquosa para uso externo.
RU2711624C2 (ru) * 2017-06-30 2020-01-17 Общество с ограниченной ответственностью "ФБК" Комбинированное средство на основе нпвс, миорелаксанта и витамина
TR201720293A2 (tr) * 2017-12-13 2019-06-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Tolperi̇zon ve non-selekti̇f cox i̇nhi̇bi̇törü kombi̇nasyonlari
WO2020086046A2 (en) * 2018-10-26 2020-04-30 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Topical compositions comprising tolperisone and flurbiprofen combination
AU2020379828A1 (en) 2019-11-06 2022-04-28 Smartech Topical, Inc. Topical formulations of cyclooxygenase inhibitors and their use
CN114939104B (zh) * 2022-06-02 2023-10-24 杭州润宠归美生物科技有限公司 一种用于减轻猫应激的外用透皮制剂、制备方法及应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6087215A (ja) * 1983-10-19 1985-05-16 Mitsui Toatsu Chem Inc 外用薬用基材
JPH06211696A (ja) * 1992-11-09 1994-08-02 Sekisui Chem Co Ltd エペリゾンまたはトルペリゾン経皮吸収製剤
JP2000143510A (ja) * 1998-11-16 2000-05-23 Taisho Pharmaceut Co Ltd 外用組成物
WO2006012146A2 (en) * 2004-06-24 2006-02-02 Idexx Laboratories, Inc. Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
JP2007532645A (ja) * 2004-04-13 2007-11-15 アルザ コーポレイション フェンタニルに基づく薬剤の経皮送達システム用の器具および方法
JP2010524977A (ja) * 2007-04-26 2010-07-22 サノヘミア・フアルマツオイテイカ・アクチエンゲゼルシヤフト 高純度の２，４’−ジメチル−３−ピペリジノ−プロピオフェノン（トルペリゾン）、これを含む医薬品組成物の製造法、並びにトルペリゾン含有活性物質組成物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0720866B2 (ja) * 1987-05-15 1995-03-08 三生製薬株式会社 エペリゾン又はトルペリゾン或いはそれらの塩類含有経皮適用製剤
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
US5252588A (en) * 1990-04-27 1993-10-12 Sekisui Kagaku Kogyo Kabushiki Kaisha Percutaneously absorbable crosslinked polyvinylpyrrolidone eperisone or tolperisone preparation
JPH0640917A (ja) * 1991-06-21 1994-02-15 Nichiban Co Ltd トルペリゾン又はエペリゾン含有ハップ剤
IT1265001B1 (it) * 1993-12-16 1996-10-17 Zambon Spa Composizione farmaceutica per uso topico contenente acido (s)-2-(4- isobutilfenil) propionico
US5733900A (en) * 1994-04-21 1998-03-31 Hisamitsu Pharmaceutical Co., Inc. Percutaneous administration base composition and percutaneous administration medicinal composition comprising said base composition and medicine
US5846620A (en) * 1997-02-06 1998-12-08 W. R. Grace & Co.-Conn. High strength flexible film package
US20020004065A1 (en) * 2000-01-20 2002-01-10 David Kanios Compositions and methods to effect the release profile in the transdermal administration of active agents
US20050163831A1 (en) * 2002-08-02 2005-07-28 Hisamitsu Pharmaceutical Co., Inc. Patch for transdermal administration
KR101105612B1 (ko) * 2003-03-18 2012-01-18 히사미쓰 세이야꾸 가부시키가이샤 비스테로이드계 소염 진통제 함유 첩부제
US20070065463A1 (en) * 2003-06-20 2007-03-22 Ronald Aung-Din Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
HUP0303313A2 (hu) * 2003-10-09 2005-07-28 Richter Gedeon Vegyészeti Gyár Rt. Transzdermális gyógyszerkészítmények
AT500144A1 (de) * 2004-03-05 2005-11-15 Sanochemia Pharmazeutika Ag Tolperison enthaltende, pharmazeutische zubereitung mit steuerbarer wirkstofffreisetzung zur oralen verabreichung
US20060004050A1 (en) * 2004-07-02 2006-01-05 Speicher Brian T Compositions and methods for the prevention or treatment of pain and other nervous system disorders
JP4782800B2 (ja) * 2004-12-17 2011-09-28 エクソンモービル・ケミカル・パテンツ・インク 均一ポリマー・ブレンドおよび該ブレンドからの製品

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6087215A (ja) * 1983-10-19 1985-05-16 Mitsui Toatsu Chem Inc 外用薬用基材
JPH06211696A (ja) * 1992-11-09 1994-08-02 Sekisui Chem Co Ltd エペリゾンまたはトルペリゾン経皮吸収製剤
JP2000143510A (ja) * 1998-11-16 2000-05-23 Taisho Pharmaceut Co Ltd 外用組成物
JP2007532645A (ja) * 2004-04-13 2007-11-15 アルザ コーポレイション フェンタニルに基づく薬剤の経皮送達システム用の器具および方法
WO2006012146A2 (en) * 2004-06-24 2006-02-02 Idexx Laboratories, Inc. Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
JP2010524977A (ja) * 2007-04-26 2010-07-22 サノヘミア・フアルマツオイテイカ・アクチエンゲゼルシヤフト 高純度の２，４’−ジメチル−３−ピペリジノ−プロピオフェノン（トルペリゾン）、これを含む医薬品組成物の製造法、並びにトルペリゾン含有活性物質組成物

Also Published As

Publication number Publication date
EP2231116A1 (en) 2010-09-29
WO2009081217A1 (en) 2009-07-02
HU0700828D0 (en) 2008-02-28
CA2709538A1 (en) 2009-07-02
EA018536B1 (ru) 2013-08-30
HUP0700828A2 (en) 2010-01-28
US20100273746A1 (en) 2010-10-28
EA201070747A1 (ru) 2010-12-30

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