EA015589B1 - Антитела против миостатина и их применение - Google Patents
Антитела против миостатина и их применение Download PDFInfo
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- EA015589B1 EA015589B1 EA200801027A EA200801027A EA015589B1 EA 015589 B1 EA015589 B1 EA 015589B1 EA 200801027 A EA200801027 A EA 200801027A EA 200801027 A EA200801027 A EA 200801027A EA 015589 B1 EA015589 B1 EA 015589B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- antibody
- myostatin
- sequence
- peptide
- zeg
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
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| PCT/US2006/038818 WO2007044411A2 (en) | 2005-10-06 | 2006-10-05 | Anti-myostatin antibodies |
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| US11180548B2 (en) | 2015-02-05 | 2021-11-23 | Chugai Seiyaku Kabushiki Kaisha | Methods of neutralizing IL-8 biological activity |
| US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| US11359194B2 (en) | 2008-04-11 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding two or more antigen molecules repeatedly |
| US11454633B2 (en) | 2014-12-19 | 2022-09-27 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use |
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| ES2533464T3 (es) | 2005-10-06 | 2015-04-10 | Eli Lilly And Company | Anticuerpos anti-miostatina |
| UA92504C2 (en) | 2005-10-12 | 2010-11-10 | Эли Лилли Энд Компани | Anti-myostatin monoclonal antibody |
| CA2647846C (en) | 2006-03-31 | 2016-06-21 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
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| EP2478905B1 (en) | 2007-06-01 | 2014-05-14 | Wyeth LLC | Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles |
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| PE20091163A1 (es) * | 2007-11-01 | 2009-08-09 | Wyeth Corp | Anticuerpos para gdf8 |
| WO2010027797A1 (en) * | 2008-08-26 | 2010-03-11 | Macrogenics Inc. | T-cell receptor antibodies and methods of use thereof |
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| AR082641A1 (es) | 2010-09-07 | 2012-12-19 | Imclone Llc | Composiciones de anticuerpo anti-vegfr-3 |
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| SMT202500263T1 (it) | 2015-09-15 | 2025-09-12 | Scholar Rock Inc | Anticorpi anti-pro-miostatina/miostatina latente e loro usi |
| KR20180094110A (ko) | 2016-01-08 | 2018-08-22 | 스칼러 락, 인크. | 항-프로/잠재성 미오스타틴 항체 및 그의 사용 방법 |
| DK3565592T5 (da) | 2017-01-06 | 2024-09-02 | Scholar Rock Inc | Behandling af stofskiftesygdomme ved inhibering af myostatinaktivering |
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| US20030138422A1 (en) * | 2001-09-26 | 2003-07-24 | Jane Aghajanian | Antibody inhibitors of GDF-8 and uses thereof |
| WO2004037861A2 (en) * | 2002-10-22 | 2004-05-06 | Wyeth | Neutralizing antibodies against gdf-8 and uses therefor |
| US20050014733A1 (en) * | 2003-06-02 | 2005-01-20 | Lisa-Anne Whittemore | Therapeutic and prophylactic methods for neuromuscular disorders |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11359194B2 (en) | 2008-04-11 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding two or more antigen molecules repeatedly |
| US11371039B2 (en) | 2008-04-11 | 2022-06-28 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
| US11454633B2 (en) | 2014-12-19 | 2022-09-27 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use |
| US12169205B2 (en) | 2014-12-19 | 2024-12-17 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
| US11180548B2 (en) | 2015-02-05 | 2021-11-23 | Chugai Seiyaku Kabushiki Kaisha | Methods of neutralizing IL-8 biological activity |
| US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| US12252532B2 (en) | 2015-12-25 | 2025-03-18 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| US11053308B2 (en) | 2016-08-05 | 2021-07-06 | Chugai Seiyaku Kabushiki Kaisha | Method for treating IL-8-related diseases |
| US11780912B2 (en) | 2016-08-05 | 2023-10-10 | Chugai Seiyaku Kabushiki Kaisha | Composition for prophylaxis or treatment of IL-8 related diseases |
Also Published As
| Publication number | Publication date |
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| KR20080045733A (ko) | 2008-05-23 |
| WO2007044411A3 (en) | 2007-08-16 |
| JP2009511480A (ja) | 2009-03-19 |
| US20100087631A1 (en) | 2010-04-08 |
| EP1951756B1 (en) | 2015-01-07 |
| NO20082073L (no) | 2008-06-17 |
| US7745583B2 (en) | 2010-06-29 |
| BRPI0616923A2 (pt) | 2011-07-05 |
| EP1951756A2 (en) | 2008-08-06 |
| WO2007044411A2 (en) | 2007-04-19 |
| ES2533464T3 (es) | 2015-04-10 |
| CA2624976A1 (en) | 2007-04-19 |
| CN101277976B (zh) | 2012-04-11 |
| CN101277976A (zh) | 2008-10-01 |
| EA200801027A1 (ru) | 2008-10-30 |
| AU2006302494A1 (en) | 2007-04-19 |
| AU2006302494B2 (en) | 2011-01-06 |
| US20080299126A1 (en) | 2008-12-04 |
| JP5052517B2 (ja) | 2012-10-17 |
| KR101135220B1 (ko) | 2012-04-24 |
| US7635760B2 (en) | 2009-12-22 |
| IL189579A0 (en) | 2008-08-07 |
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