EA013375B1 - МОДУЛЯЦИЯ ИММУНОСТИМУЛИРУЮЩИХ СВОЙСТВ КОРОТКОЙ ИНТЕРФЕРИРУЮЩЕЙ РИБОНУКЛЕИНОВОЙ КИСЛОТЫ (siРНК) С ПОМОЩЬЮ МОДИФИКАЦИИ НУКЛЕОТИДОВ - Google Patents

МОДУЛЯЦИЯ ИММУНОСТИМУЛИРУЮЩИХ СВОЙСТВ КОРОТКОЙ ИНТЕРФЕРИРУЮЩЕЙ РИБОНУКЛЕИНОВОЙ КИСЛОТЫ (siРНК) С ПОМОЩЬЮ МОДИФИКАЦИИ НУКЛЕОТИДОВ Download PDF

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Publication number
EA013375B1
EA013375B1 EA200800838A EA200800838A EA013375B1 EA 013375 B1 EA013375 B1 EA 013375B1 EA 200800838 A EA200800838 A EA 200800838A EA 200800838 A EA200800838 A EA 200800838A EA 013375 B1 EA013375 B1 EA 013375B1
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EA
Eurasian Patent Office
Prior art keywords
modification
sugar
chain
sense strand
modified nucleotide
Prior art date
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EA200800838A
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English (en)
Russian (ru)
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EA200800838A1 (ru
Inventor
Ойген Ульманн
Марион Юрк
Йорг Фолльмер
Кристиан Шеттер
Мартин Вебер
Штефан Пич
Иоанна Андреоу
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Коли Фармасьютикал Гмбх
Киаген Гмбх
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Application filed by Коли Фармасьютикал Гмбх, Киаген Гмбх filed Critical Коли Фармасьютикал Гмбх
Publication of EA200800838A1 publication Critical patent/EA200800838A1/ru
Publication of EA013375B1 publication Critical patent/EA013375B1/ru

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EA200800838A 2005-09-16 2006-09-15 МОДУЛЯЦИЯ ИММУНОСТИМУЛИРУЮЩИХ СВОЙСТВ КОРОТКОЙ ИНТЕРФЕРИРУЮЩЕЙ РИБОНУКЛЕИНОВОЙ КИСЛОТЫ (siРНК) С ПОМОЩЬЮ МОДИФИКАЦИИ НУКЛЕОТИДОВ EA013375B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71759705P 2005-09-16 2005-09-16
PCT/IB2006/003356 WO2007031877A2 (en) 2005-09-16 2006-09-15 Modulation of immunostimulatory properties of short interfering ribonucleic acid (sirna) by nucleotide modification

Publications (2)

Publication Number Publication Date
EA200800838A1 EA200800838A1 (ru) 2008-08-29
EA013375B1 true EA013375B1 (ru) 2010-04-30

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EA200800838A EA013375B1 (ru) 2005-09-16 2006-09-15 МОДУЛЯЦИЯ ИММУНОСТИМУЛИРУЮЩИХ СВОЙСТВ КОРОТКОЙ ИНТЕРФЕРИРУЮЩЕЙ РИБОНУКЛЕИНОВОЙ КИСЛОТЫ (siРНК) С ПОМОЩЬЮ МОДИФИКАЦИИ НУКЛЕОТИДОВ

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US (1) US20090306177A1 (https=)
EP (1) EP1924692A2 (https=)
JP (1) JP2009508842A (https=)
KR (1) KR20080047463A (https=)
CN (1) CN101321868A (https=)
AU (1) AU2006290435A1 (https=)
BR (1) BRPI0616069A2 (https=)
CA (1) CA2622761A1 (https=)
EA (1) EA013375B1 (https=)
IL (1) IL190154A0 (https=)
SG (1) SG165394A1 (https=)
WO (1) WO2007031877A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012138453A1 (en) * 2011-04-03 2012-10-11 The General Hospital Corporation Efficient protein expression in vivo using modified rna (mod-rna)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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