AU2006290435A1 - Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification - Google Patents

Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification Download PDF

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Publication number
AU2006290435A1
AU2006290435A1 AU2006290435A AU2006290435A AU2006290435A1 AU 2006290435 A1 AU2006290435 A1 AU 2006290435A1 AU 2006290435 A AU2006290435 A AU 2006290435A AU 2006290435 A AU2006290435 A AU 2006290435A AU 2006290435 A1 AU2006290435 A1 AU 2006290435A1
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Australia
Prior art keywords
modification
sense strand
sugar
modified nucleotide
sirna
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Abandoned
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AU2006290435A
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English (en)
Inventor
Ioanna Andreou
Marion Jurk
Stefan Pitsch
Christian Schetter
Eugen Uhlmann
Jorg Vollmer
Martin Weber
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Qiagen GmbH
Coley Pharmaceutical GmbH
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Qiagen GmbH
Coley Pharmaceutical GmbH
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Application filed by Qiagen GmbH, Coley Pharmaceutical GmbH filed Critical Qiagen GmbH
Publication of AU2006290435A1 publication Critical patent/AU2006290435A1/en
Abandoned legal-status Critical Current

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AU2006290435A 2005-09-16 2006-09-15 Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification Abandoned AU2006290435A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71759705P 2005-09-16 2005-09-16
US60/717,597 2005-09-16
PCT/IB2006/003356 WO2007031877A2 (en) 2005-09-16 2006-09-15 Modulation of immunostimulatory properties of short interfering ribonucleic acid (sirna) by nucleotide modification

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AU2006290435A1 true AU2006290435A1 (en) 2007-03-22

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AU2006290435A Abandoned AU2006290435A1 (en) 2005-09-16 2006-09-15 Modulation of immunostimulatory properties of short interfering ribonucleic acid (siRNA) by nucleotide modification

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US (1) US20090306177A1 (https=)
EP (1) EP1924692A2 (https=)
JP (1) JP2009508842A (https=)
KR (1) KR20080047463A (https=)
CN (1) CN101321868A (https=)
AU (1) AU2006290435A1 (https=)
BR (1) BRPI0616069A2 (https=)
CA (1) CA2622761A1 (https=)
EA (1) EA013375B1 (https=)
IL (1) IL190154A0 (https=)
SG (1) SG165394A1 (https=)
WO (1) WO2007031877A2 (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN102770541A (zh) * 2010-01-07 2012-11-07 夸克医药公司 包含非核苷酸突出的寡核苷酸化合物

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US7935675B1 (en) 1994-07-15 2011-05-03 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
PT1077722E (pt) 1998-05-22 2006-12-29 Coley Pharm Group Inc Produtos e composições para utilização na indução da imunidade mucosal
US7585847B2 (en) 2000-02-03 2009-09-08 Coley Pharmaceutical Group, Inc. Immunostimulatory nucleic acids for the treatment of asthma and allergy
AU2001270134B2 (en) 2000-06-22 2006-06-15 University Of Iowa Research Foundation Methods for enhancing antibody-induced cell lysis and treating cancer
US8153141B2 (en) 2002-04-04 2012-04-10 Coley Pharmaceutical Gmbh Immunostimulatory G, U-containing oligoribonucleotides
US20040053880A1 (en) 2002-07-03 2004-03-18 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7569553B2 (en) 2002-07-03 2009-08-04 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7605138B2 (en) 2002-07-03 2009-10-20 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
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