EA009771B1 - Полипептид нейбластина, способы его получения и применения - Google Patents
Полипептид нейбластина, способы его получения и применения Download PDFInfo
- Publication number
- EA009771B1 EA009771B1 EA200300852A EA200300852A EA009771B1 EA 009771 B1 EA009771 B1 EA 009771B1 EA 200300852 A EA200300852 A EA 200300852A EA 200300852 A EA200300852 A EA 200300852A EA 009771 B1 EA009771 B1 EA 009771B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- polypeptide
- neublastin
- amino acid
- νβν
- variant
- Prior art date
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- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- Veterinary Medicine (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26607101P | 2001-02-01 | 2001-02-01 | |
| PCT/US2002/002319 WO2002060929A2 (en) | 2001-02-01 | 2002-01-25 | Polymer conjugates of neublastin and methods of using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200300852A1 EA200300852A1 (ru) | 2004-06-24 |
| EA009771B1 true EA009771B1 (ru) | 2008-04-28 |
Family
ID=23013042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300852A EA009771B1 (ru) | 2001-02-01 | 2002-01-25 | Полипептид нейбластина, способы его получения и применения |
Country Status (35)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2488635C1 (ru) * | 2012-03-22 | 2013-07-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития | Способ получения рекомбинантного антиангиогенного полипептида |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| JP4259868B2 (ja) * | 2001-02-01 | 2009-04-30 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | ニューブラスチンのポリマー結合体および同様の使用方法。 |
| US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
| ES2374971T3 (es) * | 2001-03-28 | 2012-02-23 | Biogen Idec Ma Inc. | Uso de polipéptidos de neublastina para el tratamiento del dolor neuropático. |
| PT3025726T (pt) * | 2002-01-18 | 2020-01-09 | Biogen Ma Inc | Compostos do polímero polialquileno e utilizações dos mesmos |
| JP4742025B2 (ja) | 2003-01-31 | 2011-08-10 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 変異ニューブラスチンのポリマー結合体 |
| EP1897552B1 (en) | 2003-04-18 | 2009-06-17 | Biogen Idec MA Inc. | Polymer-conjugated glycosylated neublastin |
| AU2004245175C1 (en) * | 2003-06-10 | 2010-03-18 | Biogen Ma Inc. | Improved secretion of neublastin |
| US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
| CN101043899B (zh) * | 2004-08-19 | 2011-03-30 | 比奥根艾迪克Ma公司 | 重折叠转化型生长因子beta家族蛋白 |
| DK1786454T3 (da) * | 2004-08-19 | 2010-09-06 | Biogen Idec Inc | Neublastinvarianter |
| TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
| US20100056440A1 (en) * | 2006-03-01 | 2010-03-04 | Biogen Idec Ma Inc. | Compositions and methods for administering gdnf ligand family proteins |
| JP2010503630A (ja) | 2006-09-15 | 2010-02-04 | クレアビリス・セラピューティクス・エスピーエー | ＨＭＧＢ１のＢｏｘ−ＡおよびＨＭＧＢ１のＢｏｘ−Ａ変異体のポリマー複合体 |
| TWI445544B (zh) | 2007-05-01 | 2014-07-21 | Biogen Idec Inc | 增進血管形成之組合物及方法 |
| KR20140091721A (ko) * | 2011-11-02 | 2014-07-22 | 제넨테크, 인크. | 오버로드 및 용리 크로마토그래피 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770577A (en) * | 1994-11-14 | 1998-06-23 | Amgen Inc. | BDNF and NT-3 polypeptides selectively linked to polyethylene glycol |
| WO1999043813A1 (en) * | 1998-02-27 | 1999-09-02 | Regeneron Pharmaceuticals, Inc. | Modified ciliary neurotrophic factor, method of making and methods of use thereof |
| WO2000001815A2 (en) * | 1998-07-06 | 2000-01-13 | Nsgene A/S | Neurotrophic factors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000034475A2 (en) * | 1998-12-09 | 2000-06-15 | Amgen Inc. | Grnf4, a gdnf-related neurotrophic factor |
| JP4259868B2 (ja) * | 2001-02-01 | 2009-04-30 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | ニューブラスチンのポリマー結合体および同様の使用方法。 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2488635C1 (ru) * | 2012-03-22 | 2013-07-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития | Способ получения рекомбинантного антиангиогенного полипептида |
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