EA009196B1 - Ацетил 2-гидрокси-1,3-диаминоалканы - Google Patents

Ацетил 2-гидрокси-1,3-диаминоалканы Download PDF

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Publication number
EA009196B1
EA009196B1 EA200500472A EA200500472A EA009196B1 EA 009196 B1 EA009196 B1 EA 009196B1 EA 200500472 A EA200500472 A EA 200500472A EA 200500472 A EA200500472 A EA 200500472A EA 009196 B1 EA009196 B1 EA 009196B1
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EA
Eurasian Patent Office
Prior art keywords
amino
difluorobenzyl
alkyl
acetamide
optionally substituted
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EA200500472A
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English (en)
Russian (ru)
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EA200500472A1 (ru
Inventor
Мишель Майар
Эрик Т. Болдуин
Джеймс П. Бек
Роберт Хьюз
Варгиз Джон
Шон Р. Пулли
Рут Тенбринк
Original Assignee
Элан Фармасьютикалз, Инк.
Фармация Энд Апджон Компани Ллс
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Publication of EA200500472A1 publication Critical patent/EA200500472A1/ru
Publication of EA009196B1 publication Critical patent/EA009196B1/ru

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    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
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