EA008930B1 - Непэгилированные, длительно циркулирующие липосомы - Google Patents

Непэгилированные, длительно циркулирующие липосомы Download PDF

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Publication number
EA008930B1
EA008930B1 EA200500850A EA200500850A EA008930B1 EA 008930 B1 EA008930 B1 EA 008930B1 EA 200500850 A EA200500850 A EA 200500850A EA 200500850 A EA200500850 A EA 200500850A EA 008930 B1 EA008930 B1 EA 008930B1
Authority
EA
Eurasian Patent Office
Prior art keywords
liposomes
doxorubicin
composition
hydrochloride
liposome
Prior art date
Application number
EA200500850A
Other languages
English (en)
Russian (ru)
Other versions
EA200500850A1 (ru
Inventor
Гаутам Винод Дафтари
Срикантх Аннаппа Паи
Санджита Ханурмеш Риванкар
Original Assignee
Зайдус Би-Эс-Ви Рисерч Энд Дивелопмент Прайвит Лимитид
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Зайдус Би-Эс-Ви Рисерч Энд Дивелопмент Прайвит Лимитид filed Critical Зайдус Би-Эс-Ви Рисерч Энд Дивелопмент Прайвит Лимитид
Publication of EA200500850A1 publication Critical patent/EA200500850A1/ru
Publication of EA008930B1 publication Critical patent/EA008930B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA200500850A 2002-12-31 2003-12-31 Непэгилированные, длительно циркулирующие липосомы EA008930B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1101MU2002 2002-12-31
PCT/IN2003/000424 WO2004058140A2 (en) 2002-12-31 2003-12-31 Non-pegylated long-circulating liposomes

Publications (2)

Publication Number Publication Date
EA200500850A1 EA200500850A1 (ru) 2006-02-24
EA008930B1 true EA008930B1 (ru) 2007-08-31

Family

ID=32500467

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500850A EA008930B1 (ru) 2002-12-31 2003-12-31 Непэгилированные, длительно циркулирующие липосомы

Country Status (18)

Country Link
EP (1) EP1435231B8 (https=)
JP (1) JP5355842B2 (https=)
KR (2) KR101133084B1 (https=)
CN (1) CN1756533B (https=)
AT (1) ATE453381T1 (https=)
AU (1) AU2003303368B2 (https=)
BR (1) BR0317882A (https=)
CA (1) CA2511464C (https=)
DE (1) DE60330745D1 (https=)
DK (1) DK1435231T3 (https=)
EA (1) EA008930B1 (https=)
ES (1) ES2337563T3 (https=)
IL (1) IL169364A (https=)
MX (1) MXPA05007102A (https=)
NZ (1) NZ540778A (https=)
PT (1) PT1435231E (https=)
WO (1) WO2004058140A2 (https=)
ZA (1) ZA200504850B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2758669C2 (ru) * 2016-09-27 2021-11-01 Вертекс Фармасьютикалз Инкорпорейтед Способ лечения рака с применением сочетания днк-поражающих агентов и ингибиторов днк-пк

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5634862B2 (ja) * 2007-05-16 2014-12-03 カーテーベー トゥモーアフォルシュングス ゲゼルシャフト ミット ベシュレンクテル ハフツング 低粘度アントラサイクリン製剤
ES2593027T3 (es) * 2009-03-30 2016-12-05 Eisai R&D Management Co., Ltd. Composición liposomal
EP2415464B1 (en) 2009-03-30 2017-05-10 Eisai R&D Management Co., Ltd. Method for producing liposome composition
WO2012118376A1 (en) * 2011-03-01 2012-09-07 To-Bbb Holding B.V. Advanced active liposomal loading of poorly water-soluble substances
KR102666251B1 (ko) * 2014-11-25 2024-05-27 큐라디즘 약학적 조성물, 이의 제조 및 용도
US12029724B2 (en) 2016-04-28 2024-07-09 Eisai R&D Management Co., Ltd. Method for inhibiting tumor growth
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
US12036204B2 (en) 2019-07-26 2024-07-16 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
CN116570775B (zh) * 2023-05-16 2024-08-02 万瑞飞鸿(北京)医疗器材有限公司 一种药物涂层、血管支架及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
EP0561424A1 (en) * 1984-08-08 1993-09-22 The Liposome Company, Inc. Dehydrated liposomes
US5316771A (en) * 1988-09-28 1994-05-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of amphiphatic drug loading in liposomes by ammonium ion gradient

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153955A1 (en) * 1983-09-06 1985-09-11 Health Research, Inc. Liposome delivery method for decreasing the toxicity of an antitumor drug
CA1270198A (en) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
US4920016A (en) 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
CA1338702C (en) * 1987-03-05 1996-11-12 Lawrence D. Mayer High drug:lipid formulations of liposomal- antineoplastic agents
JPH0720857B2 (ja) 1988-08-11 1995-03-08 テルモ株式会社 リポソームおよびその製法
US6132763A (en) 1988-10-20 2000-10-17 Polymasc Pharmaceuticals Plc Liposomes
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
CA2263455C (en) * 1996-08-23 2002-10-29 Sequus Pharmaceuticals, Inc. Liposomes containing a cisplatin compound
BR9914601A (pt) * 1998-09-16 2001-10-23 Alza Corp Inibidor de topoisomerase capturado por lipossoma
KR20000061075A (ko) * 1999-03-23 2000-10-16 린 중친 리포솜의 응집을 방지하기 위한 방법 및 조성물
GB0111279D0 (en) * 2001-05-10 2001-06-27 Nycomed Imaging As Radiolabelled liposomes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
EP0561424A1 (en) * 1984-08-08 1993-09-22 The Liposome Company, Inc. Dehydrated liposomes
US5316771A (en) * 1988-09-28 1994-05-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of amphiphatic drug loading in liposomes by ammonium ion gradient

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2758669C2 (ru) * 2016-09-27 2021-11-01 Вертекс Фармасьютикалз Инкорпорейтед Способ лечения рака с применением сочетания днк-поражающих агентов и ингибиторов днк-пк

Also Published As

Publication number Publication date
EP1435231B1 (en) 2009-12-30
KR20110075051A (ko) 2011-07-05
AU2003303368B2 (en) 2010-06-17
EA200500850A1 (ru) 2006-02-24
JP2006513189A (ja) 2006-04-20
WO2004058140B1 (en) 2004-12-16
CN1756533A (zh) 2006-04-05
NZ540778A (en) 2008-04-30
WO2004058140A3 (en) 2004-10-28
KR101133084B1 (ko) 2012-04-04
BR0317882A (pt) 2005-12-13
CN1756533B (zh) 2010-06-16
CA2511464C (en) 2011-08-23
EP1435231A1 (en) 2004-07-07
KR101171045B1 (ko) 2012-08-03
EP1435231B8 (en) 2010-03-03
KR20050088233A (ko) 2005-09-02
PT1435231E (pt) 2010-04-08
ES2337563T3 (es) 2010-04-27
AU2003303368A1 (en) 2004-07-22
HK1089946A1 (en) 2006-12-15
ATE453381T1 (de) 2010-01-15
CA2511464A1 (en) 2004-07-15
IL169364A (en) 2012-05-31
ZA200504850B (en) 2006-08-30
DE60330745D1 (de) 2010-02-11
JP5355842B2 (ja) 2013-11-27
IL169364A0 (en) 2007-07-04
WO2004058140A2 (en) 2004-07-15
MXPA05007102A (es) 2005-08-26
DK1435231T3 (da) 2010-04-26

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Legal Events

Date Code Title Description
PC1A Registration of transfer to a eurasian application by force of assignment
HC1A Change in name of an applicant in a eurasian application
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU