EA007985B1 - Молекулы распознавания на клеточной поверхности, содержащие иммуноглобулиновый домен - Google Patents

Молекулы распознавания на клеточной поверхности, содержащие иммуноглобулиновый домен Download PDF

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Publication number
EA007985B1
EA007985B1 EA200401453A EA200401453A EA007985B1 EA 007985 B1 EA007985 B1 EA 007985B1 EA 200401453 A EA200401453 A EA 200401453A EA 200401453 A EA200401453 A EA 200401453A EA 007985 B1 EA007985 B1 EA 007985B1
Authority
EA
Eurasian Patent Office
Prior art keywords
polypeptide
nucleic acid
disease
acid molecule
present
Prior art date
Application number
EA200401453A
Other languages
English (en)
Russian (ru)
Other versions
EA200401453A1 (ru
Inventor
Эндрю Роберт Дэвидс
Ричард Джозеф Фэйган
Кристофер Бенджамин Фелпс
Кристин Пауэр
Original Assignee
Арес Трейдинг С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Арес Трейдинг С.А. filed Critical Арес Трейдинг С.А.
Publication of EA200401453A1 publication Critical patent/EA200401453A1/ru
Publication of EA007985B1 publication Critical patent/EA007985B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Pain & Pain Management (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
EA200401453A 2002-04-30 2003-04-30 Молекулы распознавания на клеточной поверхности, содержащие иммуноглобулиновый домен EA007985B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0209884.6A GB0209884D0 (en) 2002-04-30 2002-04-30 Proteins
PCT/GB2003/001851 WO2003093316A2 (en) 2002-04-30 2003-04-30 Immunoglobulin-domain containing cell surface recognition molecules

Publications (2)

Publication Number Publication Date
EA200401453A1 EA200401453A1 (ru) 2005-06-30
EA007985B1 true EA007985B1 (ru) 2007-02-27

Family

ID=9935806

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401453A EA007985B1 (ru) 2002-04-30 2003-04-30 Молекулы распознавания на клеточной поверхности, содержащие иммуноглобулиновый домен

Country Status (16)

Country Link
US (1) US7622555B2 (enExample)
EP (1) EP1499640A2 (enExample)
JP (1) JP2006502702A (enExample)
KR (1) KR20050008699A (enExample)
CN (1) CN1665840A (enExample)
AU (1) AU2003229961B2 (enExample)
BR (1) BR0309638A (enExample)
CA (1) CA2483038A1 (enExample)
EA (1) EA007985B1 (enExample)
GB (1) GB0209884D0 (enExample)
IL (1) IL164777A0 (enExample)
MX (1) MXPA04010674A (enExample)
NO (1) NO20044628L (enExample)
RS (1) RS92704A (enExample)
WO (1) WO2003093316A2 (enExample)
ZA (1) ZA200408453B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12503520B2 (en) 2022-11-10 2025-12-23 Regeneron Pharmaceuticals, Inc. Compositions and methods for making antibodies based on use of an expression-enhancing locus

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0326393D0 (en) * 2003-11-12 2003-12-17 Ares Trading Sa Cytokine antagonist molecules
WO2006120160A1 (en) * 2005-05-06 2006-11-16 Laboratoires Serono S.A. Use of an immunoglobulin domain-containing cell surface recognition molecule for treating diseases
CN100402551C (zh) * 2006-04-14 2008-07-16 中国科学院长春应用化学研究所 β2-微球蛋白的抗原表位及应用
BRPI0716060A2 (pt) 2006-08-17 2013-09-17 Boehringer Ingelheim Int inibidores de polimerase viral.
US8404235B2 (en) 2007-05-21 2013-03-26 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8252286B2 (en) 2007-05-21 2012-08-28 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8178101B2 (en) 2007-05-21 2012-05-15 Alderbio Holdings Inc. Use of anti-IL-6 antibodies having specific binding properties to treat cachexia
US8062864B2 (en) 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
US7906117B2 (en) 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
ES2721753T3 (es) 2007-05-21 2019-08-05 Alderbio Holdings Llc Anticuerpos contra IL-6 y usos de los mismos
US9701747B2 (en) 2007-05-21 2017-07-11 Alderbio Holdings Llc Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
US8992920B2 (en) 2008-11-25 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of arthritis
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
WO2011066371A2 (en) 2009-11-24 2011-06-03 Alder Biopharmaceuticals, Inc. Antibodies to il-6 and use thereof
US9775921B2 (en) 2009-11-24 2017-10-03 Alderbio Holdings Llc Subcutaneously administrable composition containing anti-IL-6 antibody
WO2012071561A2 (en) 2010-11-23 2012-05-31 Alder Biopharmaceuticals, Inc. Anti-il-6 antibodies for the treatment of anemia
CN107526942B (zh) * 2017-07-18 2021-04-20 中山大学 生命组学序列数据的反向检索方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1033041A1 (en) * 1997-11-20 2000-09-06 Airspan Networks Inc. Subscriber terminal for wireless telecommunications system
WO2001054477A2 (en) * 2000-01-25 2001-08-02 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2002034783A2 (en) * 2000-10-27 2002-05-02 Incyte Genomics, Inc. Transmembrane proteins
WO2002040671A2 (en) * 2000-11-16 2002-05-23 Incyte Genomics, Inc. Immunoglobulin superfamily proteins

Family Cites Families (5)

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US6420526B1 (en) * 1997-03-07 2002-07-16 Human Genome Sciences, Inc. 186 human secreted proteins
US6783961B1 (en) * 1999-02-26 2004-08-31 Genset S.A. Expressed sequence tags and encoded human proteins
CA2296792A1 (en) 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
WO2004007672A2 (en) 2002-07-12 2004-01-22 Nuvelo, Inc. Methods and materials relating to novel polypeptides and polynucleotides
AU2003303305A1 (en) 2002-10-02 2004-09-30 Nuvelo,Inc. Novel nucleic acids and polypeptides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1033041A1 (en) * 1997-11-20 2000-09-06 Airspan Networks Inc. Subscriber terminal for wireless telecommunications system
WO2001054477A2 (en) * 2000-01-25 2001-08-02 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2002034783A2 (en) * 2000-10-27 2002-05-02 Incyte Genomics, Inc. Transmembrane proteins
WO2002040671A2 (en) * 2000-11-16 2002-05-23 Incyte Genomics, Inc. Immunoglobulin superfamily proteins

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 'Online! EBI; 12 October 2001 (2001-10-12), TANG ET AL.: "Isolated polypeptide for treatment of diseases, diagnostics, raising antibodies and research use.", retrieved from http://WWW.EBI.AC.UK, Database accession no. AAM24238, XP002259341, abstract & WO 0154477 A (HYSEQ), 2 August 2001 (2001-08-02), the whole document *
DATABASE EMBL 'Online! EBI; 26 September 2002 (2002-09-26), WARREN ET AL.: "Transmembrane proteins", retrieved from http://WWW.EBI.AC.UK, Database accession no. AX498567, XP002259403, abstract & WO 02 34783 A (INCYTE GENOMICS), 2 May 2002 (2002-05-02) *
DATABASE EMBL 'Online! EBI; EDWARDS J.B.D.M: "Sequence Tag and encoded human protein", retrieved from http.7/WWW.EBI.AC.UK, Database accession no. BD511416, XP002259339, the whole document & EP 1 033 041 A (GENSET), 6 September 2000 (2000-09-06), the whole document *
DATABASE EMBL 'Online! EBI; SUGANO ET AL.: "NEDO human cDNA sequencing project", retrieved from http://WWW.EBI.AC.UK, Database accession no. AK098396, XP002259340, abstract *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12503520B2 (en) 2022-11-10 2025-12-23 Regeneron Pharmaceuticals, Inc. Compositions and methods for making antibodies based on use of an expression-enhancing locus

Also Published As

Publication number Publication date
AU2003229961B2 (en) 2009-02-19
EA200401453A1 (ru) 2005-06-30
IL164777A0 (en) 2005-12-18
ZA200408453B (en) 2006-07-26
CA2483038A1 (en) 2003-11-13
KR20050008699A (ko) 2005-01-21
BR0309638A (pt) 2005-03-01
US7622555B2 (en) 2009-11-24
CN1665840A (zh) 2005-09-07
NO20044628L (no) 2004-12-29
WO2003093316A3 (en) 2004-02-12
WO2003093316A2 (en) 2003-11-13
JP2006502702A (ja) 2006-01-26
US20040204352A1 (en) 2004-10-14
RS92704A (sr) 2006-12-15
MXPA04010674A (es) 2005-02-17
EP1499640A2 (en) 2005-01-26
AU2003229961A1 (en) 2003-11-17
GB0209884D0 (en) 2002-06-05

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU