CN1665840A - 含有免疫球蛋白结构域的细胞表面识别分子 - Google Patents

含有免疫球蛋白结构域的细胞表面识别分子 Download PDF

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Publication number
CN1665840A
CN1665840A CN038152525A CN03815252A CN1665840A CN 1665840 A CN1665840 A CN 1665840A CN 038152525 A CN038152525 A CN 038152525A CN 03815252 A CN03815252 A CN 03815252A CN 1665840 A CN1665840 A CN 1665840A
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CN
China
Prior art keywords
polypeptide
seq
nucleic acid
acid molecule
disease
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Pending
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CN038152525A
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English (en)
Chinese (zh)
Inventor
A·R·戴维斯
R·J·法根
C·B·菲尔普斯
C·鲍尔
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Ares Trading SA
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Ares Trading SA
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Publication of CN1665840A publication Critical patent/CN1665840A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
CN038152525A 2002-04-30 2003-04-30 含有免疫球蛋白结构域的细胞表面识别分子 Pending CN1665840A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0209884.6 2002-04-30
GBGB0209884.6A GB0209884D0 (en) 2002-04-30 2002-04-30 Proteins

Publications (1)

Publication Number Publication Date
CN1665840A true CN1665840A (zh) 2005-09-07

Family

ID=9935806

Family Applications (1)

Application Number Title Priority Date Filing Date
CN038152525A Pending CN1665840A (zh) 2002-04-30 2003-04-30 含有免疫球蛋白结构域的细胞表面识别分子

Country Status (16)

Country Link
US (1) US7622555B2 (enExample)
EP (1) EP1499640A2 (enExample)
JP (1) JP2006502702A (enExample)
KR (1) KR20050008699A (enExample)
CN (1) CN1665840A (enExample)
AU (1) AU2003229961B2 (enExample)
BR (1) BR0309638A (enExample)
CA (1) CA2483038A1 (enExample)
EA (1) EA007985B1 (enExample)
GB (1) GB0209884D0 (enExample)
IL (1) IL164777A0 (enExample)
MX (1) MXPA04010674A (enExample)
NO (1) NO20044628L (enExample)
RS (1) RS92704A (enExample)
WO (1) WO2003093316A2 (enExample)
ZA (1) ZA200408453B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100402551C (zh) * 2006-04-14 2008-07-16 中国科学院长春应用化学研究所 β2-微球蛋白的抗原表位及应用
CN107526942A (zh) * 2017-07-18 2017-12-29 中山大学 生命组学序列数据的反向检索方法
CN112592973A (zh) * 2020-12-30 2021-04-02 昆明医科大学第一附属医院 单核苷酸多态性rs1553607744在检测着色性干皮病基因中的应用

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0326393D0 (en) * 2003-11-12 2003-12-17 Ares Trading Sa Cytokine antagonist molecules
JP2008540385A (ja) * 2005-05-06 2008-11-20 ラボラトワール セローノ ソシエテ アノニム 疾患を治療するための免疫グロブリンドメイン含有細胞表面認識分子の使用
WO2008019477A1 (en) 2006-08-17 2008-02-21 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US8062864B2 (en) 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
US8178101B2 (en) 2007-05-21 2012-05-15 Alderbio Holdings Inc. Use of anti-IL-6 antibodies having specific binding properties to treat cachexia
DK2164514T3 (en) 2007-05-21 2017-02-27 Alderbio Holdings Llc Antibodies to IL-6 and its use
US8252286B2 (en) 2007-05-21 2012-08-28 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8404235B2 (en) 2007-05-21 2013-03-26 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US7906117B2 (en) 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US9701747B2 (en) 2007-05-21 2017-07-11 Alderbio Holdings Llc Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US8992920B2 (en) 2008-11-25 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of arthritis
US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
EP2504032A4 (en) 2009-11-24 2013-06-19 Alderbio Holdings Llc IL-6 ANTAGONISTS FOR PREVENTING OR TREATING THROMBOSIS
US9775921B2 (en) 2009-11-24 2017-10-03 Alderbio Holdings Llc Subcutaneously administrable composition containing anti-IL-6 antibody
US8992908B2 (en) 2010-11-23 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of oral mucositis
US11530277B2 (en) 2016-04-20 2022-12-20 Regeneron Pharmaceuticals, Inc. Compositions and methods for making antibodies based on use of an expression-enhancing locus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420526B1 (en) * 1997-03-07 2002-07-16 Human Genome Sciences, Inc. 186 human secreted proteins
GB2331666A (en) * 1997-11-20 1999-05-26 Dsc Telecom Lp Subscriber Terminal for a Wireless Telecommunications System
US6783961B1 (en) * 1999-02-26 2004-08-31 Genset S.A. Expressed sequence tags and encoded human proteins
WO2001054477A2 (en) * 2000-01-25 2001-08-02 Hyseq, Inc. Novel nucleic acids and polypeptides
CA2296792A1 (en) 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
JP2004530409A (ja) * 2000-10-27 2004-10-07 インサイト・ゲノミックス・インコーポレイテッド 膜貫通タンパク質
JP2004535759A (ja) * 2000-11-16 2004-12-02 インサイト・ゲノミックス・インコーポレイテッド 免疫グロブリンスーパファミリタンパク質
WO2004007672A2 (en) 2002-07-12 2004-01-22 Nuvelo, Inc. Methods and materials relating to novel polypeptides and polynucleotides
CA2500521A1 (en) 2002-10-02 2004-09-23 Nuvelo, Inc. Novel nucleic acids and polypeptides

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100402551C (zh) * 2006-04-14 2008-07-16 中国科学院长春应用化学研究所 β2-微球蛋白的抗原表位及应用
CN107526942A (zh) * 2017-07-18 2017-12-29 中山大学 生命组学序列数据的反向检索方法
CN107526942B (zh) * 2017-07-18 2021-04-20 中山大学 生命组学序列数据的反向检索方法
CN112592973A (zh) * 2020-12-30 2021-04-02 昆明医科大学第一附属医院 单核苷酸多态性rs1553607744在检测着色性干皮病基因中的应用

Also Published As

Publication number Publication date
KR20050008699A (ko) 2005-01-21
WO2003093316A3 (en) 2004-02-12
RS92704A (sr) 2006-12-15
WO2003093316A2 (en) 2003-11-13
EA200401453A1 (ru) 2005-06-30
NO20044628L (no) 2004-12-29
JP2006502702A (ja) 2006-01-26
EA007985B1 (ru) 2007-02-27
AU2003229961B2 (en) 2009-02-19
CA2483038A1 (en) 2003-11-13
IL164777A0 (en) 2005-12-18
US7622555B2 (en) 2009-11-24
GB0209884D0 (en) 2002-06-05
ZA200408453B (en) 2006-07-26
US20040204352A1 (en) 2004-10-14
AU2003229961A1 (en) 2003-11-17
BR0309638A (pt) 2005-03-01
MXPA04010674A (es) 2005-02-17
EP1499640A2 (en) 2005-01-26

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