EA007611B1 - Белок, имеющий в своей структуре цистиновые узлы - Google Patents

Белок, имеющий в своей структуре цистиновые узлы Download PDF

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Publication number
EA007611B1
EA007611B1 EA200400813A EA200400813A EA007611B1 EA 007611 B1 EA007611 B1 EA 007611B1 EA 200400813 A EA200400813 A EA 200400813A EA 200400813 A EA200400813 A EA 200400813A EA 007611 B1 EA007611 B1 EA 007611B1
Authority
EA
Eurasian Patent Office
Prior art keywords
polypeptide
disease
patient
nucleic acid
expression
Prior art date
Application number
EA200400813A
Other languages
English (en)
Russian (ru)
Other versions
EA200400813A1 (ru
Inventor
Марк Дуглас Дэйвис
Кристофер Бенджамин Фелпс
Ричард Джозеф Фэйган
Кристин Пауэр
Мелани Йорк
Марк Ибберсон
Original Assignee
Арес Трейдинг С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Арес Трейдинг С.А. filed Critical Арес Трейдинг С.А.
Publication of EA200400813A1 publication Critical patent/EA200400813A1/ru
Publication of EA007611B1 publication Critical patent/EA007611B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
EA200400813A 2001-12-21 2002-12-20 Белок, имеющий в своей структуре цистиновые узлы EA007611B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0130738.8A GB0130738D0 (en) 2001-12-21 2001-12-21 Protein
PCT/GB2002/005865 WO2003055911A2 (en) 2001-12-21 2002-12-20 Cystine-knot fold protein

Publications (2)

Publication Number Publication Date
EA200400813A1 EA200400813A1 (ru) 2005-04-28
EA007611B1 true EA007611B1 (ru) 2006-12-29

Family

ID=9928236

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400813A EA007611B1 (ru) 2001-12-21 2002-12-20 Белок, имеющий в своей структуре цистиновые узлы

Country Status (15)

Country Link
US (1) US7619065B2 (enExample)
EP (1) EP1463754B1 (enExample)
JP (1) JP2005528336A (enExample)
KR (1) KR20040089093A (enExample)
CN (1) CN1620466A (enExample)
AT (1) ATE397624T1 (enExample)
AU (1) AU2002353207B2 (enExample)
CA (1) CA2470781A1 (enExample)
DE (1) DE60227002D1 (enExample)
EA (1) EA007611B1 (enExample)
ES (1) ES2306802T3 (enExample)
GB (1) GB0130738D0 (enExample)
IL (2) IL162592A0 (enExample)
MX (1) MXPA04006062A (enExample)
WO (1) WO2003055911A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9752124B2 (en) 2009-02-03 2017-09-05 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium for epithelial stem cells and organoids comprising the stem cells
US9765301B2 (en) 2010-07-29 2017-09-19 Koninklijke Nederlandse Akademie Van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
US10696721B2 (en) 2015-09-15 2020-06-30 Genentech, Inc. Cystine knot scaffold platform
US10947510B2 (en) 2009-02-03 2021-03-16 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium for epithelial stem cells and organoids comprising the stem cells
US12517112B2 (en) 2017-12-21 2026-01-06 Koninklijke Nederlandse Akademie Van Wetenschappen Immune cell organoid co-cultures

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130738D0 (en) 2001-12-21 2002-02-06 Serono Internat S A Protein
US7193069B2 (en) 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
EP1755648A2 (en) 2004-05-27 2007-02-28 Acceleron Pharma Inc. Cerberus/coco derivatives and uses thereof
US9045553B2 (en) * 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
EP2010206A1 (en) * 2006-01-12 2009-01-07 Ares Trading S.A. Cystine-knot fold cytokine
JP2010512326A (ja) 2006-12-08 2010-04-22 アクセルロン ファーマ， インコーポレイテッド Ｃｅｒｂｅｒｕｓ、Ｃｏｃｏおよびこれらの誘導体の使用
US10961305B2 (en) 2016-12-21 2021-03-30 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130738D0 (en) 2001-12-21 2002-02-06 Serono Internat S A Protein
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOUWMEESTER T. ET AL.: "CERBERUS IS A HEAD-INDUCING SECRETED FACTOR EXPRESSED IN THE ANTERIOR ENDODERM OF SPEMANN'S ORGANIZER", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, Vol. 382, pp. 595-601, XP002066227, ISSN: 0028-0836, page 595, right-hand column, paragraph 2; figure 1 *
DATABASE EMBL 'Online! STRAUSBERG ET AL.: "Homo sapiens cDNA clone IMAGE: 4558384 5', mRNA sequence". Database accession no. BG330085, XP002245164, the whole document *
EIMON PETER M. ET AL.: "Xenopus Dan, a member of the Dan gene family of BMP antagonists, is expressed in derivatives of the cranial and trunk neural crest". MECHANISMS OF DEVELOPMENT, vol. 107, no. 1-2, September 2001 (2001-09), pages 187-189, XP002245163, ISSN: 0925-4773 *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9752124B2 (en) 2009-02-03 2017-09-05 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium for epithelial stem cells and organoids comprising the stem cells
US10947510B2 (en) 2009-02-03 2021-03-16 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium for epithelial stem cells and organoids comprising the stem cells
US9765301B2 (en) 2010-07-29 2017-09-19 Koninklijke Nederlandse Akademie Van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
US11034935B2 (en) 2010-07-29 2021-06-15 Koninklijke Nederlandse Akademie Van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
US12649903B2 (en) 2010-07-29 2026-06-09 Koninklijke Nederlandse Akademie Van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
US10696721B2 (en) 2015-09-15 2020-06-30 Genentech, Inc. Cystine knot scaffold platform
US11078243B2 (en) 2015-09-15 2021-08-03 Genentech, Inc. Cystine knot scaffold platform
US11155586B2 (en) 2015-09-15 2021-10-26 Genentech, Inc. Cystine knot scaffold platform
RU2770384C2 (ru) * 2015-09-15 2022-04-15 Дженентек, Инк. Платформа на основе каркаса цистинового узла
US11407794B2 (en) 2015-09-15 2022-08-09 Genetech, Inc. Cystine knot scaffold platform
US12517112B2 (en) 2017-12-21 2026-01-06 Koninklijke Nederlandse Akademie Van Wetenschappen Immune cell organoid co-cultures

Also Published As

Publication number Publication date
EP1463754A2 (en) 2004-10-06
DE60227002D1 (en) 2008-07-17
JP2005528336A (ja) 2005-09-22
US7619065B2 (en) 2009-11-17
KR20040089093A (ko) 2004-10-20
IL162592A (en) 2009-12-24
EP1463754B1 (en) 2008-06-04
WO2003055911A8 (en) 2004-02-05
CA2470781A1 (en) 2003-07-10
US20050186663A1 (en) 2005-08-25
ES2306802T3 (es) 2008-11-16
CN1620466A (zh) 2005-05-25
EA200400813A1 (ru) 2005-04-28
AU2002353207B2 (en) 2009-01-08
IL162592A0 (en) 2005-11-20
WO2003055911A2 (en) 2003-07-10
AU2002353207A1 (en) 2003-07-15
ATE397624T1 (de) 2008-06-15
GB0130738D0 (en) 2002-02-06
WO2003055911A3 (en) 2003-08-28
MXPA04006062A (es) 2004-09-27

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU