CA2470781A1 - Cystine-knot fold protein - Google Patents

Cystine-knot fold protein Download PDF

Info

Publication number
CA2470781A1
CA2470781A1 CA002470781A CA2470781A CA2470781A1 CA 2470781 A1 CA2470781 A1 CA 2470781A1 CA 002470781 A CA002470781 A CA 002470781A CA 2470781 A CA2470781 A CA 2470781A CA 2470781 A1 CA2470781 A1 CA 2470781A1
Authority
CA
Canada
Prior art keywords
polypeptide
nucleic acid
seq
acid molecule
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002470781A
Other languages
English (en)
French (fr)
Inventor
Mark Douglas Davies
Christopher Benjamin Phelps
Richard Joseph Fagan
Christine Power
Melanie Yorke
Mark Ibberson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ares Trading SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2470781A1 publication Critical patent/CA2470781A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
CA002470781A 2001-12-21 2002-12-20 Cystine-knot fold protein Abandoned CA2470781A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0130738.8 2001-12-21
GBGB0130738.8A GB0130738D0 (en) 2001-12-21 2001-12-21 Protein
PCT/GB2002/005865 WO2003055911A2 (en) 2001-12-21 2002-12-20 Cystine-knot fold protein

Publications (1)

Publication Number Publication Date
CA2470781A1 true CA2470781A1 (en) 2003-07-10

Family

ID=9928236

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002470781A Abandoned CA2470781A1 (en) 2001-12-21 2002-12-20 Cystine-knot fold protein

Country Status (15)

Country Link
US (1) US7619065B2 (enExample)
EP (1) EP1463754B1 (enExample)
JP (1) JP2005528336A (enExample)
KR (1) KR20040089093A (enExample)
CN (1) CN1620466A (enExample)
AT (1) ATE397624T1 (enExample)
AU (1) AU2002353207B2 (enExample)
CA (1) CA2470781A1 (enExample)
DE (1) DE60227002D1 (enExample)
EA (1) EA007611B1 (enExample)
ES (1) ES2306802T3 (enExample)
GB (1) GB0130738D0 (enExample)
IL (2) IL162592A0 (enExample)
MX (1) MXPA04006062A (enExample)
WO (1) WO2003055911A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130738D0 (en) 2001-12-21 2002-02-06 Serono Internat S A Protein
US7193069B2 (en) 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
WO2005115439A2 (en) 2004-05-27 2005-12-08 Acceleron Pharma Inc. Cerberus/coco derivatives and uses thereof
US9045553B2 (en) * 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
AU2006335335A1 (en) * 2006-01-12 2007-07-19 Ares Trading S.A. Cystine-knot fold cytokine
WO2008073351A2 (en) 2006-12-08 2008-06-19 Acceleron Pharma Inc. Uses of cerberus, coco and derivatives thereof
US9752124B2 (en) 2009-02-03 2017-09-05 Koninklijke Nederlandse Akademie Van Wetenschappen Culture medium for epithelial stem cells and organoids comprising the stem cells
EP3061808B1 (en) 2009-02-03 2020-08-12 Koninklijke Nederlandse Akademie van Wetenschappen Culture medium for epithelial stem cells and organoids comprising said stem cells
EP2412800A1 (en) 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
TWI799366B (zh) 2015-09-15 2023-04-21 美商建南德克公司 胱胺酸結骨架平臺
JP2020502218A (ja) 2016-12-21 2020-01-23 メレオ バイオファーマ 3 リミテッド 骨形成不全症の処置における抗スクレロスチン抗体の使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130738D0 (en) 2001-12-21 2002-02-06 Serono Internat S A Protein
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA

Also Published As

Publication number Publication date
IL162592A0 (en) 2005-11-20
WO2003055911A2 (en) 2003-07-10
CN1620466A (zh) 2005-05-25
US20050186663A1 (en) 2005-08-25
MXPA04006062A (es) 2004-09-27
AU2002353207B2 (en) 2009-01-08
US7619065B2 (en) 2009-11-17
EA200400813A1 (ru) 2005-04-28
EP1463754B1 (en) 2008-06-04
AU2002353207A1 (en) 2003-07-15
DE60227002D1 (en) 2008-07-17
IL162592A (en) 2009-12-24
ES2306802T3 (es) 2008-11-16
ATE397624T1 (de) 2008-06-15
GB0130738D0 (en) 2002-02-06
WO2003055911A8 (en) 2004-02-05
WO2003055911A3 (en) 2003-08-28
EA007611B1 (ru) 2006-12-29
KR20040089093A (ko) 2004-10-20
EP1463754A2 (en) 2004-10-06
JP2005528336A (ja) 2005-09-22

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20131104