DZ1335A1 - Procédé stéréospecifique pour la préparation des énantiomères de la furo (3,4-c) pyridine et composéainsi obtenus. - Google Patents
Procédé stéréospecifique pour la préparation des énantiomères de la furo (3,4-c) pyridine et composéainsi obtenus.Info
- Publication number
- DZ1335A1 DZ1335A1 DZ890060A DZ890060A DZ1335A1 DZ 1335 A1 DZ1335 A1 DZ 1335A1 DZ 890060 A DZ890060 A DZ 890060A DZ 890060 A DZ890060 A DZ 890060A DZ 1335 A1 DZ1335 A1 DZ 1335A1
- Authority
- DZ
- Algeria
- Prior art keywords
- furo
- enantiomers
- pyridine
- compound
- preparation
- Prior art date
Links
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- GJVNMIQVQXYJCP-UHFFFAOYSA-N furo[3,4-c]pyridine Chemical compound C1=NC=CC2=[C]OC=C21 GJVNMIQVQXYJCP-UHFFFAOYSA-N 0.000 title 1
- 230000000707 stereoselective effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888808001A GB8808001D0 (en) | 1988-04-06 | 1988-04-06 | Stereospecific preparative process for furol(3,4-c)pyridine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DZ1335A1 true DZ1335A1 (fr) | 2004-09-13 |
Family
ID=10634633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DZ890060A DZ1335A1 (fr) | 1988-04-06 | 1989-04-01 | Procédé stéréospecifique pour la préparation des énantiomères de la furo (3,4-c) pyridine et composéainsi obtenus. |
Country Status (28)
Country | Link |
---|---|
US (1) | US5026855A (en:Method) |
EP (1) | EP0337858B1 (en:Method) |
JP (1) | JP2680456B2 (en:Method) |
KR (1) | KR970005308B1 (en:Method) |
AT (1) | AT397093B (en:Method) |
AU (1) | AU616753B2 (en:Method) |
BE (1) | BE1003843A4 (en:Method) |
CA (1) | CA1338475C (en:Method) |
CH (1) | CH680000A5 (en:Method) |
DK (1) | DK167020B1 (en:Method) |
DZ (1) | DZ1335A1 (en:Method) |
ES (1) | ES2057159T3 (en:Method) |
FI (1) | FI93116C (en:Method) |
FR (2) | FR2629821B1 (en:Method) |
GB (2) | GB8808001D0 (en:Method) |
IE (1) | IE61915B1 (en:Method) |
IN (1) | IN172987B (en:Method) |
MA (1) | MA21529A1 (en:Method) |
MY (1) | MY104424A (en:Method) |
NL (1) | NL8920307A (en:Method) |
NZ (1) | NZ228614A (en:Method) |
OA (1) | OA09247A (en:Method) |
PT (1) | PT90210B (en:Method) |
SE (1) | SE509130C2 (en:Method) |
SG (1) | SG40492G (en:Method) |
TN (1) | TNSN89043A1 (en:Method) |
WO (1) | WO1989009772A1 (en:Method) |
ZA (1) | ZA892477B (en:Method) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8808001D0 (en) * | 1988-04-06 | 1988-05-05 | Scras | Stereospecific preparative process for furol(3,4-c)pyridine derivatives |
GB8907480D0 (en) * | 1989-04-03 | 1989-05-17 | Scaras Societe De Conseils De | Separation of insomers of furo(3,4-c)pyridine derivatives |
GB8917168D0 (en) * | 1989-07-27 | 1989-09-13 | Scras | Asymmetric synthesis of furo(3,4-c)pyridine derivatives |
US5130252A (en) * | 1990-05-14 | 1992-07-14 | Synthetech, Inc. | Resolution of furopyridine enantiomers and synthetic precursors thereof |
US20060089374A1 (en) * | 2003-07-17 | 2006-04-27 | Glenn Cornett | Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease |
GB2423927A (en) * | 2003-08-29 | 2006-09-13 | Cotherix Inc | Combination Of Cicletanine And An Oral Antidiabetic And/Or Blood Lipid-Lowering Agent For Treating Diabetes And Metabolic Syndrome |
US20060154959A1 (en) * | 2005-01-13 | 2006-07-13 | Navitas Pharma | Combination therapies of cicletanine and carvedilol |
US20070141174A1 (en) * | 2005-01-13 | 2007-06-21 | Navitas Pharma, Inc. | Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension |
US20080096915A1 (en) * | 2005-01-13 | 2008-04-24 | Greenberg Traurig LLP | Compositions for the treatment of metabolic disorders |
US20070105817A1 (en) * | 2005-11-09 | 2007-05-10 | Jim Page | Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension |
WO2008085872A1 (en) * | 2007-01-03 | 2008-07-17 | Cornett Glenn V | Cicletanine and pkc inhibitors in the treatment of pulmonary and cardiac disorders |
AR073259A1 (es) * | 2008-07-29 | 2010-10-28 | Merck & Co Inc | Derivados de furosemida utiles como diureticos |
EP2485734B1 (en) * | 2009-10-09 | 2014-07-02 | Merck Sharp & Dohme Corp. | Diuretics |
US9522138B2 (en) * | 2013-12-31 | 2016-12-20 | Don C. Rockey | Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4244951A (en) * | 1979-05-16 | 1981-01-13 | Pfizer Inc. | Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide |
IN156817B (en:Method) * | 1981-02-10 | 1985-11-09 | Scras | |
ZA842029B (en) * | 1983-04-05 | 1984-10-31 | Scras | Furo-(3,4-c)-pyridine derivatives preparation thereof and therapeutic compositions containing the same |
GB2137618B (en) * | 1983-04-05 | 1986-05-08 | Scras | Furo-(3,4-c)-pyridine derivatives |
US4735950A (en) * | 1983-04-05 | 1988-04-05 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) | Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same |
IN160104B (en:Method) * | 1983-04-05 | 1987-06-27 | Scras | |
GB8327817D0 (en) * | 1983-10-18 | 1983-11-16 | Scras | 4-halo-furo-(3 4-c)-pyridine derivatives |
GB8330517D0 (en) * | 1983-11-16 | 1983-12-21 | Scras | 6-vinyl-furo-(3,4-c)pyridine derivatives |
GB8330658D0 (en) * | 1983-11-17 | 1983-12-29 | Scras | 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives |
GB8402740D0 (en) * | 1984-02-02 | 1984-03-07 | Scras | Furo-(3 4-c)-pyridine derivatives |
GB8414559D0 (en) * | 1984-06-07 | 1984-07-11 | Scras | Pyridine derivatives |
GB8422029D0 (en) * | 1984-08-31 | 1984-10-03 | Scras | 6-substituted-furo-(3 4-c)-pyridine derivatives |
GB8422379D0 (en) * | 1984-09-05 | 1984-10-10 | Scras | Derivatives |
GB8427218D0 (en) * | 1984-10-27 | 1984-12-05 | Scras | Pyridine derivatives |
DE3519693A1 (de) * | 1985-06-01 | 1987-01-02 | Basf Ag | Pyridin-derivate, ihre herstellung und verwendung |
GB8808001D0 (en) * | 1988-04-06 | 1988-05-05 | Scras | Stereospecific preparative process for furol(3,4-c)pyridine derivatives |
GB8907480D0 (en) * | 1989-04-03 | 1989-05-17 | Scaras Societe De Conseils De | Separation of insomers of furo(3,4-c)pyridine derivatives |
-
1988
- 1988-04-06 GB GB888808001A patent/GB8808001D0/en active Pending
-
1989
- 1989-04-01 DZ DZ890060A patent/DZ1335A1/fr active
- 1989-04-04 MA MA21776A patent/MA21529A1/fr unknown
- 1989-04-04 IN IN312DE1989 patent/IN172987B/en unknown
- 1989-04-04 ZA ZA892477A patent/ZA892477B/xx unknown
- 1989-04-05 BE BE8900379A patent/BE1003843A4/fr not_active IP Right Cessation
- 1989-04-05 IE IE107689A patent/IE61915B1/en not_active IP Right Cessation
- 1989-04-05 CA CA000595814A patent/CA1338475C/en not_active Expired - Fee Related
- 1989-04-05 NZ NZ228614A patent/NZ228614A/en unknown
- 1989-04-06 MY MYPI89000437A patent/MY104424A/en unknown
- 1989-04-06 JP JP1504150A patent/JP2680456B2/ja not_active Expired - Fee Related
- 1989-04-06 PT PT90210A patent/PT90210B/pt not_active IP Right Cessation
- 1989-04-06 CH CH4339/89A patent/CH680000A5/fr not_active IP Right Cessation
- 1989-04-06 ES ES89400956T patent/ES2057159T3/es not_active Expired - Lifetime
- 1989-04-06 WO PCT/FR1989/000157 patent/WO1989009772A1/fr active IP Right Grant
- 1989-04-06 FR FR8904540A patent/FR2629821B1/fr not_active Expired - Lifetime
- 1989-04-06 KR KR1019890702267A patent/KR970005308B1/ko not_active Expired - Fee Related
- 1989-04-06 EP EP89400956A patent/EP0337858B1/fr not_active Expired - Lifetime
- 1989-04-06 AU AU34190/89A patent/AU616753B2/en not_active Ceased
- 1989-04-06 FR FR8904539A patent/FR2629820B1/fr not_active Expired - Fee Related
- 1989-04-06 TN TNTNSN89043A patent/TNSN89043A1/fr unknown
- 1989-04-06 NL NL8920307A patent/NL8920307A/nl active Search and Examination
- 1989-04-06 GB GB8927509A patent/GB2235194B/en not_active Expired - Lifetime
- 1989-04-06 AT AT0900589A patent/AT397093B/de not_active IP Right Cessation
- 1989-11-28 US US07/449,946 patent/US5026855A/en not_active Expired - Lifetime
- 1989-12-05 DK DK611689A patent/DK167020B1/da not_active IP Right Cessation
- 1989-12-05 SE SE8904104A patent/SE509130C2/sv not_active IP Right Cessation
- 1989-12-05 FI FI895826A patent/FI93116C/fi not_active IP Right Cessation
- 1989-12-10 OA OA59691A patent/OA09247A/xx unknown
-
1992
- 1992-04-14 SG SG404/92A patent/SG40492G/en unknown
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