DK77986A - Ekstrusionsmetoder til fremstilling af liposomer - Google Patents
Ekstrusionsmetoder til fremstilling af liposomer Download PDFInfo
- Publication number
- DK77986A DK77986A DK77986A DK77986A DK77986A DK 77986 A DK77986 A DK 77986A DK 77986 A DK77986 A DK 77986A DK 77986 A DK77986 A DK 77986A DK 77986 A DK77986 A DK 77986A
- Authority
- DK
- Denmark
- Prior art keywords
- extrusion methods
- preparing liposomes
- liposomes
- preparing
- extrusion
- Prior art date
Links
- 238000001125 extrusion Methods 0.000 title 1
- 239000002502 liposome Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/08—Flat membrane modules
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62269084A | 1984-06-20 | 1984-06-20 | |
US62250284A | 1984-06-20 | 1984-06-20 | |
US62269084 | 1984-06-20 | ||
US62250284 | 1984-06-20 | ||
US8501161 | 1985-06-19 | ||
PCT/US1985/001161 WO1986000238A1 (en) | 1984-06-20 | 1985-06-19 | Extrusion techniques for producing liposomes |
Publications (3)
Publication Number | Publication Date |
---|---|
DK77986D0 DK77986D0 (da) | 1986-02-19 |
DK77986A true DK77986A (da) | 1986-02-19 |
DK173397B1 DK173397B1 (da) | 2000-09-18 |
Family
ID=27089214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198600779A DK173397B1 (da) | 1984-06-20 | 1986-02-19 | Fremgangsmåder til fremstilling af liposomer samt fremgangsmåde til forøgelse af homogeniteten af en population af liposome |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0185756B1 (da) |
JP (1) | JP2537186B2 (da) |
CA (1) | CA1264668C (da) |
DE (1) | DE3579426D1 (da) |
DK (1) | DK173397B1 (da) |
ES (1) | ES8608922A1 (da) |
GR (1) | GR851485B (da) |
IE (1) | IE58630B1 (da) |
PT (1) | PT80678B (da) |
SG (1) | SG21092G (da) |
WO (1) | WO1986000238A1 (da) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5231112A (en) * | 1984-04-12 | 1993-07-27 | The Liposome Company, Inc. | Compositions containing tris salt of cholesterol hemisuccinate and antifungal |
US5897873A (en) * | 1984-04-12 | 1999-04-27 | The Liposome Company, Inc. | Affinity associated vaccine |
US5077056A (en) * | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
US5736155A (en) * | 1984-08-08 | 1998-04-07 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
US5059421A (en) * | 1985-07-26 | 1991-10-22 | The Liposome Company, Inc. | Preparation of targeted liposome systems of a defined size distribution |
MX9203291A (es) * | 1985-06-26 | 1992-08-01 | Liposome Co Inc | Metodo para acoplamiento de liposomas. |
US5041278A (en) * | 1985-10-15 | 1991-08-20 | The Liposome Company, Inc. | Alpha tocopherol-based vesicles |
US4737323A (en) * | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
US6759057B1 (en) | 1986-06-12 | 2004-07-06 | The Liposome Company, Inc. | Methods and compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs |
US5252263A (en) * | 1986-06-16 | 1993-10-12 | The Liposome Company, Inc. | Induction of asymmetry in vesicles |
CA1338702C (en) * | 1987-03-05 | 1996-11-12 | Lawrence D. Mayer | High drug:lipid formulations of liposomal- antineoplastic agents |
US5616334A (en) * | 1987-03-05 | 1997-04-01 | The Liposome Company, Inc. | Low toxicity drug-lipid systems |
US6406713B1 (en) | 1987-03-05 | 2002-06-18 | The Liposome Company, Inc. | Methods of preparing low-toxicity drug-lipid complexes |
MX9203808A (es) * | 1987-03-05 | 1992-07-01 | Liposome Co Inc | Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos. |
WO1988007850A1 (en) * | 1987-04-16 | 1988-10-20 | The Liposome Company, Inc. | Liposome continuous size reduction method and apparatus |
US5262168A (en) * | 1987-05-22 | 1993-11-16 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
US5082664A (en) * | 1987-05-22 | 1992-01-21 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
US5925375A (en) * | 1987-05-22 | 1999-07-20 | The Liposome Company, Inc. | Therapeutic use of multilamellar liposomal prostaglandin formulations |
MX9203804A (es) * | 1987-10-19 | 1992-07-01 | Liposome Co Inc | Sistemas farmaceuticos a base de tocoferol. |
US5948441A (en) * | 1988-03-07 | 1999-09-07 | The Liposome Company, Inc. | Method for size separation of particles |
DE3812816A1 (de) * | 1988-04-16 | 1989-11-02 | Lawaczeck Ruediger Dipl Phys P | Verfahren zur solubilisierung von liposomen und/oder biologischer membranen sowie deren verwendung |
JPH04501723A (ja) * | 1988-11-09 | 1992-03-26 | アンガー,エヴァン,シー. | リポソーム性放射線造影剤 |
US5049392A (en) * | 1989-01-18 | 1991-09-17 | The Liposome Company, Inc. | Osmotically dependent vesicles |
DK0478715T3 (da) * | 1989-06-23 | 1996-08-05 | Liposome Co Inc | Målrettede liposomer og fremgangsmåder til liposom-protein-kobling |
US5469854A (en) * | 1989-12-22 | 1995-11-28 | Imarx Pharmaceutical Corp. | Methods of preparing gas-filled liposomes |
US5149319A (en) * | 1990-09-11 | 1992-09-22 | Unger Evan C | Methods for providing localized therapeutic heat to biological tissues and fluids |
US5542935A (en) * | 1989-12-22 | 1996-08-06 | Imarx Pharmaceutical Corp. | Therapeutic delivery systems related applications |
US5352435A (en) * | 1989-12-22 | 1994-10-04 | Unger Evan C | Ionophore containing liposomes for ultrasound imaging |
US5580575A (en) * | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
US5820848A (en) * | 1990-01-12 | 1998-10-13 | The Liposome Company, Inc. | Methods of preparing interdigitation-fusion liposomes and gels which encapsulate a bioactive agent |
US5525232A (en) * | 1990-03-02 | 1996-06-11 | The Liposome Company, Inc. | Method for entrapment of cationic species in lemellar vesicles |
ATE138803T1 (de) * | 1990-07-31 | 1996-06-15 | Liposome Co Inc | Anhäufung von aminosäuren und peptiden in liposomen |
CA2091776C (en) * | 1990-10-05 | 1999-08-31 | Royden M. Coe | Liposome extrusion process |
US6623671B2 (en) | 1990-10-05 | 2003-09-23 | Royden M. Coe | Liposome extrusion process |
EP0804944A3 (en) | 1992-05-04 | 1998-08-26 | UNGER, Evan C | A method of providing a gas composition in a biological tissue or fluid in vivo |
AU5174193A (en) * | 1992-10-16 | 1994-05-09 | Georg Rossling | Process and device for producing liquid, dispersed systems |
DE69429511T2 (de) * | 1993-05-21 | 2002-05-16 | Liposome Co Inc | Reduzierung von durch liposome induzierte physiologischen gegenreaktionen |
US5716526A (en) * | 1994-01-14 | 1998-02-10 | The Liposome Company, Inc. | Method of separating materials from liposomes or lipid complexes |
US5622715A (en) * | 1994-06-10 | 1997-04-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method of improving renal function |
US6235308B1 (en) | 1994-06-10 | 2001-05-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Method of treating hypertension |
DE19515163C2 (de) * | 1995-01-31 | 2002-11-28 | Erich Politsch | Vorrichtung zur Extrusion von Suspensionen |
US5902604A (en) | 1995-06-06 | 1999-05-11 | Board Of Regents, The University Of Texas System | Submicron liposome suspensions obtained from preliposome lyophilizates |
NL1001380C2 (nl) * | 1995-10-09 | 1997-04-11 | Fuji Photo Film Bv | Methode voor het dispergeren van een geëmulgeerd materiaal van het olie-druppeltype in een vloeistoftoevoersysteem en bekledingsmethode waarbij van een dergelijke dispergeermethode gebruik wordt gemaakt. |
CA2208215A1 (en) | 1995-10-12 | 1997-04-17 | Supergen, Inc. | Liposome formulations of 5.beta. steroids |
DE19542499A1 (de) * | 1995-11-15 | 1997-05-22 | Bayer Ag | Verfahren und Vorrichtung zur Herstellung einer parenteralen Arzneistoffzubereitung |
IT1289939B1 (it) * | 1997-02-20 | 1998-10-19 | Angelini Ricerche Spa | Composizione farmaceutica acquosa comprendente un principio attivo altamente insolubile in acqua |
US20010003580A1 (en) | 1998-01-14 | 2001-06-14 | Poh K. Hui | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend |
NZ529347A (en) | 2001-04-04 | 2008-01-31 | Nordic Vaccine Technology As | Use of at least one sterol capable of interacting with a nucleic acid and at least saponin to form immunostimulating complexes ( IMSCO ) |
PT1560641E (pt) | 2002-11-14 | 2006-07-31 | Leuven K U Res & Dev | Metodo para a preparacao de emulsoes |
JP2005170923A (ja) * | 2003-10-21 | 2005-06-30 | Konica Minolta Medical & Graphic Inc | リポソーム含有x線造影剤およびその製造方法 |
JP2005170928A (ja) * | 2003-10-21 | 2005-06-30 | Konica Minolta Medical & Graphic Inc | リポソーム含有x線造影剤およびその製造方法 |
JP4654590B2 (ja) * | 2004-03-31 | 2011-03-23 | コニカミノルタエムジー株式会社 | X線ct用造影組成物およびその製造方法 |
ES2641272T3 (es) | 2006-04-28 | 2017-11-08 | Children's Hospital Medical Center | Composiciones que comprenden proteínas o polipéptidos fusogénicos derivados de la prosaposina para aplicación en sistemas de suministro de fármacos transmembrana |
KR20080012605A (ko) | 2006-08-04 | 2008-02-12 | 삼성에스디아이 주식회사 | 탄성 에너지 장벽을 이용한 생체막 소자 |
EP1920765A1 (en) * | 2006-11-07 | 2008-05-14 | Medigene AG | Liposome preparation by single-pass process |
US9445975B2 (en) | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
JP5771366B2 (ja) | 2009-09-02 | 2015-08-26 | 株式会社バイオメッドコア | リポソーム製造装置及び方法 |
EP2646107A2 (en) | 2010-12-01 | 2013-10-09 | Spinal Modulation Inc. | Agent delivery systems for selective neuromodulation |
US20150216998A1 (en) | 2012-01-01 | 2015-08-06 | Ramot At Tel-Aviv University Ltd. | Endo180-targeted particles for selective delivery of therapeutic and diagnostic agents |
ES2874305T3 (es) * | 2013-03-14 | 2021-11-04 | Zuli Holdings Ltd | Formulación y fabricación de liposomas |
US9993427B2 (en) | 2013-03-14 | 2018-06-12 | Biorest Ltd. | Liposome formulation and manufacture |
US11246832B2 (en) * | 2016-06-28 | 2022-02-15 | Verily Life Sciences Llc | Serial filtration to generate small cholesterol-containing liposomes |
JP6403026B2 (ja) * | 2017-06-29 | 2018-10-10 | バイオレスト リミテッド | リポソーム、リポソームを含む処方剤、および処方剤の製造方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5186117A (en) * | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
US4263428A (en) * | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
CA1173360A (en) * | 1979-06-22 | 1984-08-28 | Jurg Schrank | Pharmaceutical preparations |
JPS5782310A (en) * | 1980-11-11 | 1982-05-22 | Tanabe Seiyaku Co Ltd | Production of liposome preparation |
-
1985
- 1985-06-07 CA CA483485A patent/CA1264668C/en not_active Expired
- 1985-06-18 IE IE151485A patent/IE58630B1/en not_active IP Right Cessation
- 1985-06-18 GR GR851485A patent/GR851485B/el unknown
- 1985-06-19 WO PCT/US1985/001161 patent/WO1986000238A1/en active IP Right Grant
- 1985-06-19 DE DE8585903513T patent/DE3579426D1/de not_active Expired - Lifetime
- 1985-06-19 JP JP60502838A patent/JP2537186B2/ja not_active Expired - Lifetime
- 1985-06-19 EP EP85903513A patent/EP0185756B1/en not_active Expired - Lifetime
- 1985-06-19 ES ES544364A patent/ES8608922A1/es not_active Expired
- 1985-06-20 PT PT80678A patent/PT80678B/pt unknown
-
1986
- 1986-02-19 DK DK198600779A patent/DK173397B1/da not_active IP Right Cessation
-
1992
- 1992-03-04 SG SG210/92A patent/SG21092G/en unknown
Also Published As
Publication number | Publication date |
---|---|
SG21092G (en) | 1992-04-16 |
DK77986D0 (da) | 1986-02-19 |
JP2537186B2 (ja) | 1996-09-25 |
JPS61502452A (ja) | 1986-10-30 |
ES544364A0 (es) | 1986-09-01 |
IE58630B1 (en) | 1993-10-20 |
IE851514L (en) | 1985-12-20 |
PT80678A (en) | 1985-07-01 |
WO1986000238A1 (en) | 1986-01-16 |
ES8608922A1 (es) | 1986-09-01 |
CA1264668A (en) | 1990-01-23 |
DE3579426D1 (de) | 1990-10-04 |
GR851485B (da) | 1985-11-25 |
CA1264668C (en) | 1990-01-23 |
EP0185756B1 (en) | 1990-08-29 |
EP0185756A4 (en) | 1987-09-02 |
EP0185756A1 (en) | 1986-07-02 |
PT80678B (pt) | 1987-08-19 |
DK173397B1 (da) | 2000-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |