DK301986D0 - Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser - Google Patents

Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser

Info

Publication number
DK301986D0
DK301986D0 DK301986A DK301986A DK301986D0 DK 301986 D0 DK301986 D0 DK 301986D0 DK 301986 A DK301986 A DK 301986A DK 301986 A DK301986 A DK 301986A DK 301986 D0 DK301986 D0 DK 301986D0
Authority
DK
Denmark
Prior art keywords
hydroxyvitamin
preparing
compounds
Prior art date
Application number
DK301986A
Other languages
English (en)
Other versions
DK153943B (da
DK301986A (da
DK153943C (da
Inventor
Hector F Deluca
Heinrich K Schnoes
Seok Ho Lee
Mary E Phelps
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK301986A publication Critical patent/DK301986A/da
Publication of DK301986D0 publication Critical patent/DK301986D0/da
Publication of DK153943B publication Critical patent/DK153943B/da
Application granted granted Critical
Publication of DK153943C publication Critical patent/DK153943C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK301986A 1984-11-01 1986-06-26 Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser ud fra 1-hydroxy-3,5-cyclovitamin-d-forbindelser DK153943C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66729684 1984-11-01
US06/667,296 US4555364A (en) 1984-11-01 1984-11-01 Method for preparing 1-hydroxyvitamin D compounds
US8501995 1985-10-15
PCT/US1985/001995 WO1986002649A1 (en) 1984-11-01 1985-10-15 Method for preparing 1-hydroxyvitamin d compounds

Publications (4)

Publication Number Publication Date
DK301986A DK301986A (da) 1986-06-26
DK301986D0 true DK301986D0 (da) 1986-06-26
DK153943B DK153943B (da) 1988-09-26
DK153943C DK153943C (da) 1989-01-30

Family

ID=24677643

Family Applications (1)

Application Number Title Priority Date Filing Date
DK301986A DK153943C (da) 1984-11-01 1986-06-26 Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser ud fra 1-hydroxy-3,5-cyclovitamin-d-forbindelser

Country Status (12)

Country Link
US (1) US4555364A (da)
EP (1) EP0198892B1 (da)
JP (1) JPS62500717A (da)
KR (1) KR920004488B1 (da)
AU (1) AU589580B2 (da)
CA (1) CA1233187A (da)
DE (1) DE3581200D1 (da)
DK (1) DK153943C (da)
IE (1) IE58164B1 (da)
IL (1) IL76754A (da)
NZ (1) NZ213844A (da)
WO (1) WO1986002649A1 (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869473A (en) * 1988-08-02 1999-02-09 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US5602116A (en) * 1988-08-02 1997-02-11 Bone Care International, Inc. Method for treating and preventing secondary hyperparathyroidism
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5763429A (en) * 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
US5869472A (en) * 1994-07-18 1999-02-09 Bone Care International, Inc. Synthesis of 1α-hydroxy vitamin D
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US6376479B1 (en) 1995-04-03 2002-04-23 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
NZ336924A (en) * 1997-02-13 2001-06-29 Bone Care Int Inc Targeted therapeutic delivery of vitamin D compounds via a Vitamin D conjugate
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
WO2002006218A2 (en) * 2000-07-18 2002-01-24 Bone Care International, Inc. STABILIZED 1α-HYDROXY VITAMIN D
US7148211B2 (en) 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20050239756A1 (en) * 2004-04-23 2005-10-27 Bone Care International, Inc. Methods of treating various vitamin D metabolism conditions with 1alpha-hydroxyvitamin D2
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
EP1945185B1 (en) * 2005-10-12 2016-02-03 Proventiv Therapeutics, LLC Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency
HUE056937T2 (hu) 2006-02-03 2022-04-28 Opko Renal Llc A D-vitamin elégtelenség és hiány kezelése 25-hidroxivitamin D2-vel és 25-hidroxivitamin D3-mal
PT2679228T (pt) * 2006-06-21 2018-04-16 Opko Ireland Global Holdings Ltd Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d
WO2008134523A1 (en) 2007-04-25 2008-11-06 Proventiv Therapeutics, Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
KR101959952B1 (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
PT2148684E (pt) * 2007-04-25 2013-04-19 Cytochroma Inc Método de tratamento para a insuficiência e deficiência de vitamina d
WO2008134518A2 (en) * 2007-04-25 2008-11-06 Cytochroma Inc. Methods and compounds for vitamin d therapy
WO2009124210A1 (en) 2008-04-02 2009-10-08 Cytochroma Inc. Methods, compositions, uses, and kits useful for vitamin d deficiency and related disorders
US11672809B2 (en) 2010-03-29 2023-06-13 Eirgen Pharma Ltd. Methods and compositions for reducing parathyroid levels
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
AU2015298858A1 (en) 2014-08-07 2017-03-02 Opko Ireland Global Holdings Ltd. Adjunctive therapy with 25-hydroxyvitamin D
CA3018019A1 (en) 2016-03-28 2017-10-26 Opko Ireland Global Holdings, Limited Methods of vitamin d treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4234495A (en) * 1979-09-10 1980-11-18 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxyvitamin D compounds from 1α-hydroxy-3,5-cyclovitamin D compounds
US4367177A (en) * 1981-04-15 1983-01-04 Wisconsin Alumni Research Foundation Process for preparing 23,25-dihydroxyvitamin D3
US4512925A (en) * 1983-09-14 1985-04-23 Wisconsin Alumini Research Foundation 1,23-Dihydroxyvitamin D compounds
US4554106A (en) * 1984-11-01 1985-11-19 Wisconsin Alumni Research Foundation Method for preparing 1α-hydroxyvitamin D compounds

Also Published As

Publication number Publication date
CA1233187A (en) 1988-02-23
DK153943B (da) 1988-09-26
IL76754A0 (en) 1986-02-28
JPS62500717A (ja) 1987-03-26
KR860700353A (ko) 1986-10-06
DK301986A (da) 1986-06-26
IE852706L (en) 1986-05-01
AU4867485A (en) 1986-05-15
EP0198892A4 (en) 1987-03-12
EP0198892B1 (en) 1990-12-27
US4555364A (en) 1985-11-26
WO1986002649A1 (en) 1986-05-09
KR920004488B1 (ko) 1992-06-05
NZ213844A (en) 1989-08-29
AU589580B2 (en) 1989-10-19
DE3581200D1 (de) 1991-02-07
JPH0432062B2 (da) 1992-05-28
IL76754A (en) 1989-10-31
EP0198892A1 (en) 1986-10-29
DK153943C (da) 1989-01-30
IE58164B1 (en) 1993-07-28

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