DK301986A - Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser - Google Patents

Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser Download PDF

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Publication number
DK301986A
DK301986A DK301986A DK301986A DK301986A DK 301986 A DK301986 A DK 301986A DK 301986 A DK301986 A DK 301986A DK 301986 A DK301986 A DK 301986A DK 301986 A DK301986 A DK 301986A
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DK
Denmark
Prior art keywords
hydroxyvitamin
preparing
compounds
Prior art date
Application number
DK301986A
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English (en)
Other versions
DK153943C (da
DK153943B (da
DK301986D0 (da
Inventor
Hector F Deluca
Heinrich K Schnoes
Seok Ho Lee
Mary E Phelps
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK301986A publication Critical patent/DK301986A/da
Publication of DK301986D0 publication Critical patent/DK301986D0/da
Publication of DK153943B publication Critical patent/DK153943B/da
Application granted granted Critical
Publication of DK153943C publication Critical patent/DK153943C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
DK301986A 1984-11-01 1986-06-26 Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser ud fra 1-hydroxy-3,5-cyclovitamin-d-forbindelser DK153943C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66729684 1984-11-01
US06/667,296 US4555364A (en) 1984-11-01 1984-11-01 Method for preparing 1-hydroxyvitamin D compounds
US8501995 1985-10-15
PCT/US1985/001995 WO1986002649A1 (en) 1984-11-01 1985-10-15 Method for preparing 1-hydroxyvitamin d compounds

Publications (4)

Publication Number Publication Date
DK301986A true DK301986A (da) 1986-06-26
DK301986D0 DK301986D0 (da) 1986-06-26
DK153943B DK153943B (da) 1988-09-26
DK153943C DK153943C (da) 1989-01-30

Family

ID=24677643

Family Applications (1)

Application Number Title Priority Date Filing Date
DK301986A DK153943C (da) 1984-11-01 1986-06-26 Fremgangsmaade til fremstilling af 1-hydroxyvitamin-d-forbindelser ud fra 1-hydroxy-3,5-cyclovitamin-d-forbindelser

Country Status (12)

Country Link
US (1) US4555364A (da)
EP (1) EP0198892B1 (da)
JP (1) JPS62500717A (da)
KR (1) KR920004488B1 (da)
AU (1) AU589580B2 (da)
CA (1) CA1233187A (da)
DE (1) DE3581200D1 (da)
DK (1) DK153943C (da)
IE (1) IE58164B1 (da)
IL (1) IL76754A (da)
NZ (1) NZ213844A (da)
WO (1) WO1986002649A1 (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602116A (en) * 1988-08-02 1997-02-11 Bone Care International, Inc. Method for treating and preventing secondary hyperparathyroidism
US5869473A (en) * 1988-08-02 1999-02-09 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
US5801164A (en) * 1990-09-21 1998-09-01 Bone Care International, Inc. Methods of treating osteoporosis prophylactically or therapeutically
US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US6025346A (en) * 1990-09-21 2000-02-15 Bone Care International, Inc. 1α-hydroxy vitamin D4 and novel intermediates and analogues
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5763429A (en) 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
US5869472A (en) * 1994-07-18 1999-02-09 Bone Care International, Inc. Synthesis of 1α-hydroxy vitamin D
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US6376479B1 (en) 1995-04-03 2002-04-23 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6242434B1 (en) 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
JP2001511811A (ja) * 1997-02-13 2001-08-14 ボーン ケア インターナショナル インコーポレイテッド ビタミンｄ化合物の標的治療放出
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
CA2414407A1 (en) * 2000-07-18 2002-01-24 Bone Care International, Inc. Stabilized 1.alpha.-hydroxy vitamin d
US7148211B2 (en) 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20050239756A1 (en) * 2004-04-23 2005-10-27 Bone Care International, Inc. Methods of treating various vitamin D metabolism conditions with 1alpha-hydroxyvitamin D2
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
CA2924200C (en) * 2005-10-12 2017-09-05 Proventiv Therapeutics, Llc Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency
CA2882048C (en) 2006-02-03 2020-03-24 Proventiv Therapeutics, Llc Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3
ES2497494T3 (es) 2006-06-21 2014-09-23 Opko Renal, Llc Método de tratamiento y prevención del hiperparatiroidismo secundario
WO2008134518A2 (en) * 2007-04-25 2008-11-06 Cytochroma Inc. Methods and compounds for vitamin d therapy
KR20190028822A (ko) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 비타민 ｄ 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물
WO2009047644A2 (en) * 2007-04-25 2009-04-16 Cytochroma Inc. Method of treating vitamin d insufficiency and deficiency
WO2008134523A1 (en) 2007-04-25 2008-11-06 Proventiv Therapeutics, Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
US8962239B2 (en) 2008-04-02 2015-02-24 Opko Renal, Llc Methods useful for vitamin D deficiency and related disorders
PT2552484T (pt) 2010-03-29 2020-04-03 Opko Ireland Global Holdings Ltd Métodos e composições para redução dos níveis de parafróides
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
EP3193925A2 (en) 2014-08-07 2017-07-26 OPKO Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin d
IL290855B1 (en) 2016-03-28 2024-02-01 Eirgen Pharma Ltd Treatment methods using vitamin D

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4234495A (en) * 1979-09-10 1980-11-18 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxyvitamin D compounds from 1α-hydroxy-3,5-cyclovitamin D compounds
US4367177A (en) * 1981-04-15 1983-01-04 Wisconsin Alumni Research Foundation Process for preparing 23,25-dihydroxyvitamin D3
US4512925A (en) * 1983-09-14 1985-04-23 Wisconsin Alumini Research Foundation 1,23-Dihydroxyvitamin D compounds
US4554106A (en) * 1984-11-01 1985-11-19 Wisconsin Alumni Research Foundation Method for preparing 1α-hydroxyvitamin D compounds

Also Published As

Publication number Publication date
DE3581200D1 (de) 1991-02-07
JPS62500717A (ja) 1987-03-26
EP0198892B1 (en) 1990-12-27
CA1233187A (en) 1988-02-23
US4555364A (en) 1985-11-26
EP0198892A1 (en) 1986-10-29
IL76754A0 (en) 1986-02-28
KR860700353A (ko) 1986-10-06
IE58164B1 (en) 1993-07-28
DK153943C (da) 1989-01-30
DK153943B (da) 1988-09-26
JPH0432062B2 (da) 1992-05-28
NZ213844A (en) 1989-08-29
AU589580B2 (en) 1989-10-19
EP0198892A4 (en) 1987-03-12
DK301986D0 (da) 1986-06-26
WO1986002649A1 (en) 1986-05-09
AU4867485A (en) 1986-05-15
KR920004488B1 (ko) 1992-06-05
IL76754A (en) 1989-10-31
IE852706L (en) 1986-05-01

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