DK504889A - N-heterocykliske forbindelser - Google Patents

N-heterocykliske forbindelser

Info

Publication number
DK504889A
DK504889A DK504889A DK504889A DK504889A DK 504889 A DK504889 A DK 504889A DK 504889 A DK504889 A DK 504889A DK 504889 A DK504889 A DK 504889A DK 504889 A DK504889 A DK 504889A
Authority
DK
Denmark
Prior art keywords
sulphur
nitrogen
chem
oxygen
group
Prior art date
Application number
DK504889A
Other languages
English (en)
Other versions
DK504889D0 (da
Inventor
Barry Sidney Orlek
Richard Eric Faulkner
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888824071A external-priority patent/GB8824071D0/en
Priority claimed from GB888830223A external-priority patent/GB8830223D0/en
Priority claimed from GB898920660A external-priority patent/GB8920660D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK504889D0 publication Critical patent/DK504889D0/da
Publication of DK504889A publication Critical patent/DK504889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK504889A 1988-10-13 1989-10-11 N-heterocykliske forbindelser DK504889A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888824071A GB8824071D0 (en) 1988-10-13 1988-10-13 Novel compounds
GB888830223A GB8830223D0 (en) 1988-12-23 1988-12-23 Novel compounds
GB898920660A GB8920660D0 (en) 1989-09-18 1989-09-18 Novel compounds

Publications (2)

Publication Number Publication Date
DK504889D0 DK504889D0 (da) 1989-10-11
DK504889A true DK504889A (da) 1990-04-14

Family

ID=27264121

Family Applications (1)

Application Number Title Priority Date Filing Date
DK504889A DK504889A (da) 1988-10-13 1989-10-11 N-heterocykliske forbindelser

Country Status (9)

Country Link
US (1) US5166357A (da)
EP (1) EP0366304B1 (da)
JP (1) JP2934743B2 (da)
AT (1) ATE165095T1 (da)
AU (1) AU4278289A (da)
CA (1) CA2000041A1 (da)
DE (1) DE68928644T2 (da)
DK (1) DK504889A (da)
PT (1) PT91956B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
EP0402056A3 (en) * 1989-06-06 1991-09-04 Beecham Group p.l.c. Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
DE69030695T2 (de) * 1989-08-16 1998-01-08 Beecham Group Plc Azabicyclische Verbindungen
ATE136031T1 (de) * 1989-10-07 1996-04-15 Beecham Group Plc Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
JPH06502616A (ja) * 1990-12-21 1994-03-24 メルク　シヤープ　エンド　ドーム　リミテツド 治療用化合物
EP0871627A1 (en) * 1995-09-22 1998-10-21 Novo Nordisk A/S Novel substituted azacyclic or azabicyclic compounds
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
DE60015944T2 (de) * 1999-03-30 2005-11-03 E.I. Du Pont De Nemours And Co., Wilmington Verfahren zur herstellung von alpha-methylenelactonen und alpha-substitutierten hydrocarbyliden-lactonen
WO2000058297A2 (en) * 1999-03-30 2000-10-05 E.I. Du Pont De Nemours And Company PROCESS FOR THE PREPARATION OF α-METHYLENE LACTONES
US6362346B1 (en) 1999-11-12 2002-03-26 E. I. Du Pont De Nemours And Company Process for the preparation of α-methylene-γ-butyrolactone and α-acetoxymethyl-γ-butyrolactone
US6642346B2 (en) 2000-02-28 2003-11-04 E. I. Du Pont De Nemours And Company Coating compositions containing substituted and unsubstituted exomethylene lactone or lactam monomers
US6531616B2 (en) 2000-12-22 2003-03-11 E. I. Du Pont De Nemours And Company Process for the preparation of a-methylenelactones and a-substituted hydrocarbylidene lactones
KR100428408B1 (ko) * 2001-12-14 2004-04-28 학교법인 성균관대학 α-메틸렌-γ-부티로락톤의 제조방법
TW200301764A (en) 2002-01-07 2003-07-16 Du Pont Methylenelactone synthesis in supercritical fluids
AU2003235758A1 (en) 2002-01-07 2003-07-24 E.I. Du Pont De Nemours And Company Alpha-methylenelactone synthesis in supercritical fluids
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) * 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
WO2008030651A1 (en) * 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
CN102276559B (zh) * 2011-08-12 2014-05-28 河北威远生化农药有限公司 3-羟甲基四氢呋喃的合成方法
WO2023151894A1 (en) 2022-02-11 2023-08-17 Henkel Ag & Co. Kgaa Process for the synthesis of alpha-methylene-gamma-butyrolactone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
DE3789039T2 (de) * 1986-06-27 1994-06-09 Beecham Group Plc Verbrückte bicyclische N-heterocyclische Verbindungen.
ATE133415T1 (de) * 1987-04-15 1996-02-15 Beecham Group Plc Am brückenkopf substituierte azabicyclenderivate
DE3877470T2 (de) * 1987-09-10 1993-06-24 Merck Sharp & Dohme Oxazole und thiazole zur behandlung seniler demenz.
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0322182A3 (en) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE68928644D1 (de) 1998-05-20
PT91956B (pt) 1995-05-31
PT91956A (pt) 1990-04-30
US5166357A (en) 1992-11-24
JPH02134380A (ja) 1990-05-23
CA2000041A1 (en) 1990-04-13
EP0366304A3 (en) 1991-09-11
EP0366304A2 (en) 1990-05-02
EP0366304B1 (en) 1998-04-15
AU4278289A (en) 1990-04-26
JP2934743B2 (ja) 1999-08-16
DE68928644T2 (de) 1998-08-27
ATE165095T1 (de) 1998-05-15
DK504889D0 (da) 1989-10-11

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Legal Events

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