DK504889A - N-heterocykliske forbindelser - Google Patents
N-heterocykliske forbindelserInfo
- Publication number
- DK504889A DK504889A DK504889A DK504889A DK504889A DK 504889 A DK504889 A DK 504889A DK 504889 A DK504889 A DK 504889A DK 504889 A DK504889 A DK 504889A DK 504889 A DK504889 A DK 504889A
- Authority
- DK
- Denmark
- Prior art keywords
- sulphur
- nitrogen
- chem
- oxygen
- group
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 6
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 4
- 239000005864 Sulphur Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 229910052760 oxygen Inorganic materials 0.000 abstract 3
- 239000001301 oxygen Substances 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- 125000006650 (C2-C4) alkynyl group Chemical group 0.000 abstract 1
- 101100294115 Caenorhabditis elegans nhr-4 gene Proteins 0.000 abstract 1
- 101100295741 Gallus gallus COR4 gene Proteins 0.000 abstract 1
- 101100134922 Gallus gallus COR5 gene Proteins 0.000 abstract 1
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888824071A GB8824071D0 (en) | 1988-10-13 | 1988-10-13 | Novel compounds |
| GB888830223A GB8830223D0 (en) | 1988-12-23 | 1988-12-23 | Novel compounds |
| GB898920660A GB8920660D0 (en) | 1989-09-18 | 1989-09-18 | Novel compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK504889D0 DK504889D0 (da) | 1989-10-11 |
| DK504889A true DK504889A (da) | 1990-04-14 |
Family
ID=27264121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK504889A DK504889A (da) | 1988-10-13 | 1989-10-11 | N-heterocykliske forbindelser |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5166357A (da) |
| EP (1) | EP0366304B1 (da) |
| JP (1) | JP2934743B2 (da) |
| AT (1) | ATE165095T1 (da) |
| AU (1) | AU4278289A (da) |
| CA (1) | CA2000041A1 (da) |
| DE (1) | DE68928644T2 (da) |
| DK (1) | DK504889A (da) |
| PT (1) | PT91956B (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ227684A (en) * | 1988-01-30 | 1991-07-26 | Merck Sharp & Dohme | Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions |
| EP0402056A3 (en) * | 1989-06-06 | 1991-09-04 | Beecham Group p.l.c. | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
| EP0413545B1 (en) * | 1989-08-16 | 1997-05-14 | Beecham Group Plc | Azabicyclic compounds |
| ATE136031T1 (de) * | 1989-10-07 | 1996-04-15 | Beecham Group Plc | Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
| JPH06502616A (ja) * | 1990-12-21 | 1994-03-24 | メルク シヤープ エンド ドーム リミテツド | 治療用化合物 |
| AU7125096A (en) * | 1995-09-22 | 1997-04-09 | Novo Nordisk A/S | Novel substituted azacyclic or azabicyclic compounds |
| US5733912A (en) * | 1997-02-19 | 1998-03-31 | Abbott Laboratories | 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission |
| JP2002540201A (ja) * | 1999-03-30 | 2002-11-26 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | α‐メチレンラクトンおよびα‐置換ハイドロカルビリデンラクトンの製造方法 |
| KR20010111581A (ko) | 1999-03-30 | 2001-12-19 | 메리 이. 보울러 | α-메틸렌락톤의 제조 방법 |
| US6362346B1 (en) | 1999-11-12 | 2002-03-26 | E. I. Du Pont De Nemours And Company | Process for the preparation of α-methylene-γ-butyrolactone and α-acetoxymethyl-γ-butyrolactone |
| US6642346B2 (en) | 2000-02-28 | 2003-11-04 | E. I. Du Pont De Nemours And Company | Coating compositions containing substituted and unsubstituted exomethylene lactone or lactam monomers |
| US6531616B2 (en) | 2000-12-22 | 2003-03-11 | E. I. Du Pont De Nemours And Company | Process for the preparation of a-methylenelactones and a-substituted hydrocarbylidene lactones |
| KR100428408B1 (ko) * | 2001-12-14 | 2004-04-28 | 학교법인 성균관대학 | α-메틸렌-γ-부티로락톤의 제조방법 |
| KR20040081112A (ko) | 2002-01-07 | 2004-09-20 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 초임계 유체에서의 메틸렌락톤 합성 |
| JP2005515220A (ja) | 2002-01-07 | 2005-05-26 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 超臨界流体中におけるアルファ−メチレンラクトン類の合成 |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| JP2009506069A (ja) * | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| WO2008030651A1 (en) * | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| CN102276559B (zh) * | 2011-08-12 | 2014-05-28 | 河北威远生化农药有限公司 | 3-羟甲基四氢呋喃的合成方法 |
| WO2023151894A1 (en) | 2022-02-11 | 2023-08-17 | Henkel Ag & Co. Kgaa | Process for the synthesis of alpha-methylene-gamma-butyrolactone |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
| ES2061502T3 (es) * | 1986-06-27 | 1994-12-16 | Beecham Group Plc | Nuevos n-heterociclos biciclicos puenteados. |
| GB8615785D0 (en) * | 1986-06-27 | 1986-08-06 | Beecham Group Plc | Compounds |
| EP0287356B1 (en) * | 1987-04-15 | 1996-01-24 | Beecham Group Plc | Bridgehead substituted azabicyclic derivatives |
| NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
| EP0307141B1 (en) * | 1987-09-10 | 1993-01-13 | MERCK SHARP & DOHME LTD. | Oxazoles and thiazoles for the treatment of senile dementia |
| IE63906B1 (en) * | 1987-11-13 | 1995-06-14 | Novo Nordisk As | Azabicyclic compounds and their preparation and use |
| EP0322182A3 (en) * | 1987-12-22 | 1992-01-02 | Beecham Group Plc | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
-
1989
- 1989-10-02 CA CA002000041A patent/CA2000041A1/en not_active Abandoned
- 1989-10-10 US US07/418,649 patent/US5166357A/en not_active Expired - Fee Related
- 1989-10-11 EP EP89310406A patent/EP0366304B1/en not_active Expired - Lifetime
- 1989-10-11 DE DE68928644T patent/DE68928644T2/de not_active Expired - Fee Related
- 1989-10-11 DK DK504889A patent/DK504889A/da not_active Application Discontinuation
- 1989-10-11 AT AT89310406T patent/ATE165095T1/de not_active IP Right Cessation
- 1989-10-11 AU AU42782/89A patent/AU4278289A/en not_active Abandoned
- 1989-10-11 PT PT91956A patent/PT91956B/pt not_active IP Right Cessation
- 1989-10-12 JP JP1264089A patent/JP2934743B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5166357A (en) | 1992-11-24 |
| DE68928644T2 (de) | 1998-08-27 |
| PT91956A (pt) | 1990-04-30 |
| CA2000041A1 (en) | 1990-04-13 |
| AU4278289A (en) | 1990-04-26 |
| EP0366304A2 (en) | 1990-05-02 |
| PT91956B (pt) | 1995-05-31 |
| ATE165095T1 (de) | 1998-05-15 |
| EP0366304B1 (en) | 1998-04-15 |
| DK504889D0 (da) | 1989-10-11 |
| JPH02134380A (ja) | 1990-05-23 |
| DE68928644D1 (de) | 1998-05-20 |
| EP0366304A3 (en) | 1991-09-11 |
| JP2934743B2 (ja) | 1999-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |