DE68928644T2 - Heterocyclische Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen - Google Patents
Heterocyclische Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische ZubereitungenInfo
- Publication number
- DE68928644T2 DE68928644T2 DE68928644T DE68928644T DE68928644T2 DE 68928644 T2 DE68928644 T2 DE 68928644T2 DE 68928644 T DE68928644 T DE 68928644T DE 68928644 T DE68928644 T DE 68928644T DE 68928644 T2 DE68928644 T2 DE 68928644T2
- Authority
- DE
- Germany
- Prior art keywords
- sulphur
- nitrogen
- chem
- oxygen
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Photoreceptors In Electrophotography (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888824071A GB8824071D0 (en) | 1988-10-13 | 1988-10-13 | Novel compounds |
GB888830223A GB8830223D0 (en) | 1988-12-23 | 1988-12-23 | Novel compounds |
GB898920660A GB8920660D0 (en) | 1989-09-18 | 1989-09-18 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68928644D1 DE68928644D1 (de) | 1998-05-20 |
DE68928644T2 true DE68928644T2 (de) | 1998-08-27 |
Family
ID=27264121
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68928644T Expired - Fee Related DE68928644T2 (de) | 1988-10-13 | 1989-10-11 | Heterocyclische Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
Country Status (9)
Country | Link |
---|---|
US (1) | US5166357A (de) |
EP (1) | EP0366304B1 (de) |
JP (1) | JP2934743B2 (de) |
AT (1) | ATE165095T1 (de) |
AU (1) | AU4278289A (de) |
CA (1) | CA2000041A1 (de) |
DE (1) | DE68928644T2 (de) |
DK (1) | DK504889A (de) |
PT (1) | PT91956B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ227684A (en) * | 1988-01-30 | 1991-07-26 | Merck Sharp & Dohme | Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions |
EP0402056A3 (de) * | 1989-06-06 | 1991-09-04 | Beecham Group p.l.c. | Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
EP0413545B1 (de) * | 1989-08-16 | 1997-05-14 | Beecham Group Plc | Azabicyclische Verbindungen |
ATE136031T1 (de) * | 1989-10-07 | 1996-04-15 | Beecham Group Plc | Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
EP0563036A1 (de) * | 1990-12-21 | 1993-10-06 | Merck Sharp & Dohme Ltd. | 4-azatricyclo[2.2.1.0 2,6]heptanderivate und arzneimittel |
AU7125096A (en) * | 1995-09-22 | 1997-04-09 | Novo Nordisk A/S | Novel substituted azacyclic or azabicyclic compounds |
US5733912A (en) * | 1997-02-19 | 1998-03-31 | Abbott Laboratories | 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission |
CN1204131C (zh) | 1999-03-30 | 2005-06-01 | 纳幕尔杜邦公司 | 制备α-亚甲基内酯的方法 |
WO2000058298A2 (en) * | 1999-03-30 | 2000-10-05 | E.I. Du Pont De Nemours And Company | PROCESS FOR THE PREPARATION OF α-METHYLENELACTONES AND α-SUBSTITUTED HYDROCARBYLIDENE LACTONES |
US6362346B1 (en) | 1999-11-12 | 2002-03-26 | E. I. Du Pont De Nemours And Company | Process for the preparation of α-methylene-γ-butyrolactone and α-acetoxymethyl-γ-butyrolactone |
US6642346B2 (en) | 2000-02-28 | 2003-11-04 | E. I. Du Pont De Nemours And Company | Coating compositions containing substituted and unsubstituted exomethylene lactone or lactam monomers |
US6531616B2 (en) | 2000-12-22 | 2003-03-11 | E. I. Du Pont De Nemours And Company | Process for the preparation of a-methylenelactones and a-substituted hydrocarbylidene lactones |
KR100428408B1 (ko) * | 2001-12-14 | 2004-04-28 | 학교법인 성균관대학 | α-메틸렌-γ-부티로락톤의 제조방법 |
DE60301127T2 (de) | 2002-01-07 | 2006-04-20 | E.I. Du Pont De Nemours And Co., Wilmington | Methylenlacton synthese in superkritischen flüssigkeiten |
WO2003057686A1 (en) | 2002-01-07 | 2003-07-17 | E.I. Du Pont De Nemours And Company | Alpha-methylenelactone synthesis in supercritical fluids |
CA2620333A1 (en) * | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258358A3 (de) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenese mit Acetylcholinesterasehemmer |
MX2009002496A (es) * | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
CN102276559B (zh) * | 2011-08-12 | 2014-05-28 | 河北威远生化农药有限公司 | 3-羟甲基四氢呋喃的合成方法 |
WO2023151894A1 (en) | 2022-02-11 | 2023-08-17 | Henkel Ag & Co. Kgaa | Process for the synthesis of alpha-methylene-gamma-butyrolactone |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
GB8615785D0 (en) * | 1986-06-27 | 1986-08-06 | Beecham Group Plc | Compounds |
EP0261763B1 (de) * | 1986-06-27 | 1994-02-09 | Beecham Group Plc | Verbrückte bicyclische N-heterocyclische Verbindungen |
ATE133415T1 (de) * | 1987-04-15 | 1996-02-15 | Beecham Group Plc | Am brückenkopf substituierte azabicyclenderivate |
NZ225999A (en) * | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
DE3877470T2 (de) * | 1987-09-10 | 1993-06-24 | Merck Sharp & Dohme | Oxazole und thiazole zur behandlung seniler demenz. |
IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
EP0322182A3 (de) * | 1987-12-22 | 1992-01-02 | Beecham Group Plc | Azabicyclische-Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
-
1989
- 1989-10-02 CA CA002000041A patent/CA2000041A1/en not_active Abandoned
- 1989-10-10 US US07/418,649 patent/US5166357A/en not_active Expired - Fee Related
- 1989-10-11 DE DE68928644T patent/DE68928644T2/de not_active Expired - Fee Related
- 1989-10-11 AU AU42782/89A patent/AU4278289A/en not_active Abandoned
- 1989-10-11 PT PT91956A patent/PT91956B/pt not_active IP Right Cessation
- 1989-10-11 EP EP89310406A patent/EP0366304B1/de not_active Expired - Lifetime
- 1989-10-11 AT AT89310406T patent/ATE165095T1/de not_active IP Right Cessation
- 1989-10-11 DK DK504889A patent/DK504889A/da not_active Application Discontinuation
- 1989-10-12 JP JP1264089A patent/JP2934743B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK504889A (da) | 1990-04-14 |
US5166357A (en) | 1992-11-24 |
JP2934743B2 (ja) | 1999-08-16 |
EP0366304A2 (de) | 1990-05-02 |
PT91956B (pt) | 1995-05-31 |
AU4278289A (en) | 1990-04-26 |
EP0366304A3 (de) | 1991-09-11 |
PT91956A (pt) | 1990-04-30 |
ATE165095T1 (de) | 1998-05-15 |
DE68928644D1 (de) | 1998-05-20 |
EP0366304B1 (de) | 1998-04-15 |
CA2000041A1 (en) | 1990-04-13 |
JPH02134380A (ja) | 1990-05-23 |
DK504889D0 (da) | 1989-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |