DK504889D0 - Hidtil ukendte forbindelser - Google Patents

Hidtil ukendte forbindelser

Info

Publication number
DK504889D0
DK504889D0 DK504889A DK504889A DK504889D0 DK 504889 D0 DK504889 D0 DK 504889D0 DK 504889 A DK504889 A DK 504889A DK 504889 A DK504889 A DK 504889A DK 504889 D0 DK504889 D0 DK 504889D0
Authority
DK
Denmark
Prior art keywords
sulphur
nitrogen
chem
oxygen
group
Prior art date
Application number
DK504889A
Other languages
English (en)
Other versions
DK504889A (da
Inventor
Barry Sidney Orlek
Richard Eric Faulkner
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888824071A external-priority patent/GB8824071D0/en
Priority claimed from GB888830223A external-priority patent/GB8830223D0/en
Priority claimed from GB898920660A external-priority patent/GB8920660D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK504889D0 publication Critical patent/DK504889D0/da
Publication of DK504889A publication Critical patent/DK504889A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
DK504889A 1988-10-13 1989-10-11 N-heterocykliske forbindelser DK504889A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888824071A GB8824071D0 (en) 1988-10-13 1988-10-13 Novel compounds
GB888830223A GB8830223D0 (en) 1988-12-23 1988-12-23 Novel compounds
GB898920660A GB8920660D0 (en) 1989-09-18 1989-09-18 Novel compounds

Publications (2)

Publication Number Publication Date
DK504889D0 true DK504889D0 (da) 1989-10-11
DK504889A DK504889A (da) 1990-04-14

Family

ID=27264121

Family Applications (1)

Application Number Title Priority Date Filing Date
DK504889A DK504889A (da) 1988-10-13 1989-10-11 N-heterocykliske forbindelser

Country Status (9)

Country Link
US (1) US5166357A (da)
EP (1) EP0366304B1 (da)
JP (1) JP2934743B2 (da)
AT (1) ATE165095T1 (da)
AU (1) AU4278289A (da)
CA (1) CA2000041A1 (da)
DE (1) DE68928644T2 (da)
DK (1) DK504889A (da)
PT (1) PT91956B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
EP0402056A3 (en) * 1989-06-06 1991-09-04 Beecham Group p.l.c. Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
EP0413545B1 (en) * 1989-08-16 1997-05-14 Beecham Group Plc Azabicyclic compounds
DE69026197T2 (de) * 1989-10-07 1997-01-09 Beecham Group Plc Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
JPH06502616A (ja) * 1990-12-21 1994-03-24 メルク シヤープ エンド ドーム リミテツド 治療用化合物
JPH11512444A (ja) * 1995-09-22 1999-10-26 ノボ ノルディスク アクティーゼルスカブ 新規置換アザ環式またはアザ二環式化合物
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
CN1345316A (zh) * 1999-03-30 2002-04-17 纳幕尔杜邦公司 α-亚甲基内酯和α-取代的亚烃基内酯的制备方法
CA2361037A1 (en) 1999-03-30 2000-10-05 Leo E. Manzer Process for the preparation of .alpha.-methylene lactones
US6362346B1 (en) 1999-11-12 2002-03-26 E. I. Du Pont De Nemours And Company Process for the preparation of α-methylene-γ-butyrolactone and α-acetoxymethyl-γ-butyrolactone
US6642346B2 (en) 2000-02-28 2003-11-04 E. I. Du Pont De Nemours And Company Coating compositions containing substituted and unsubstituted exomethylene lactone or lactam monomers
US6531616B2 (en) 2000-12-22 2003-03-11 E. I. Du Pont De Nemours And Company Process for the preparation of a-methylenelactones and a-substituted hydrocarbylidene lactones
KR100428408B1 (ko) * 2001-12-14 2004-04-28 학교법인 성균관대학 α-메틸렌-γ-부티로락톤의 제조방법
JP2005515220A (ja) 2002-01-07 2005-05-26 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 超臨界流体中におけるアルファ−メチレンラクトン類の合成
TW200301764A (en) 2002-01-07 2003-07-16 Du Pont Methylenelactone synthesis in supercritical fluids
WO2007025177A2 (en) * 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2010502722A (ja) * 2006-09-08 2010-01-28 ブレインセルス,インコーポレイティド 4−アシルアミノピリジン誘導体を含む組み合わせ
CN102276559B (zh) * 2011-08-12 2014-05-28 河北威远生化农药有限公司 3-羟甲基四氢呋喃的合成方法
WO2023151894A1 (en) 2022-02-11 2023-08-17 Henkel Ag & Co. Kgaa Process for the synthesis of alpha-methylene-gamma-butyrolactone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
EP0261763B1 (en) * 1986-06-27 1994-02-09 Beecham Group Plc Novel bridged bicyclic N-heterocycles
GB8615785D0 (en) * 1986-06-27 1986-08-06 Beecham Group Plc Compounds
DK202388A (da) * 1987-04-15 1988-10-16 Beecham Group Plc Azabicycliske forbindelser og fremgangsmaade til fremstilling deraf
DE3877470T2 (de) * 1987-09-10 1993-06-24 Merck Sharp & Dohme Oxazole und thiazole zur behandlung seniler demenz.
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
EP0322182A3 (en) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK504889A (da) 1990-04-14
EP0366304B1 (en) 1998-04-15
DE68928644T2 (de) 1998-08-27
AU4278289A (en) 1990-04-26
PT91956B (pt) 1995-05-31
DE68928644D1 (de) 1998-05-20
ATE165095T1 (de) 1998-05-15
EP0366304A2 (en) 1990-05-02
JPH02134380A (ja) 1990-05-23
EP0366304A3 (en) 1991-09-11
PT91956A (pt) 1990-04-30
CA2000041A1 (en) 1990-04-13
US5166357A (en) 1992-11-24
JP2934743B2 (ja) 1999-08-16

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Legal Events

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AHS Application shelved for other reasons than non-payment