DK417789A - Rekombineret saccharomyces - Google Patents

Rekombineret saccharomyces

Info

Publication number
DK417789A
DK417789A DK417789A DK417789A DK417789A DK 417789 A DK417789 A DK 417789A DK 417789 A DK417789 A DK 417789A DK 417789 A DK417789 A DK 417789A DK 417789 A DK417789 A DK 417789A
Authority
DK
Denmark
Prior art keywords
recombined
saccharomyces
recombined saccharomyces
Prior art date
Application number
DK417789A
Other languages
Danish (da)
English (en)
Other versions
DK417789D0 (da
Inventor
Claudine Bruck
Joseph Cohen
Jessica Angell Gorman
Yigal Koltin
Camille Locht
Frans Van Wijnendaele
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK417789D0 publication Critical patent/DK417789D0/da
Publication of DK417789A publication Critical patent/DK417789A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/495Transforming growth factor [TGF]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2428Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK417789A 1988-08-25 1989-08-24 Rekombineret saccharomyces DK417789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23669988A 1988-08-25 1988-08-25

Publications (2)

Publication Number Publication Date
DK417789D0 DK417789D0 (da) 1989-08-24
DK417789A true DK417789A (da) 1990-02-26

Family

ID=22890585

Family Applications (1)

Application Number Title Priority Date Filing Date
DK417789A DK417789A (da) 1988-08-25 1989-08-24 Rekombineret saccharomyces

Country Status (6)

Country Link
EP (1) EP0362179A3 (fr)
JP (1) JPH02163074A (fr)
AU (1) AU4005289A (fr)
DK (1) DK417789A (fr)
PT (1) PT91554A (fr)
ZA (1) ZA896459B (fr)

Families Citing this family (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991005863A1 (fr) * 1989-10-11 1991-05-02 Pitman-Moore Australia Limited Facteurs de croissance recombinants
US5665585A (en) * 1992-09-03 1997-09-09 Alko-Yhiot Oy Recombinant production of glucoamylase P in trichoderma
DE4441197C1 (de) * 1994-11-18 1996-03-28 Deutsches Krebsforsch Expressionsplasmide für Hefe
US6030945A (en) * 1996-01-09 2000-02-29 Genentech, Inc. Apo-2 ligand
US6998116B1 (en) 1996-01-09 2006-02-14 Genentech, Inc. Apo-2 ligand
US6469144B1 (en) 1996-04-01 2002-10-22 Genentech, Inc. Apo-2LI and Apo-3 polypeptides
US5851984A (en) * 1996-08-16 1998-12-22 Genentech, Inc. Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
US6159462A (en) * 1996-08-16 2000-12-12 Genentech, Inc. Uses of Wnt polypeptides
US6462176B1 (en) 1996-09-23 2002-10-08 Genentech, Inc. Apo-3 polypeptide
US6342369B1 (en) 1997-05-15 2002-01-29 Genentech, Inc. Apo-2-receptor
AU739350B2 (en) 1997-06-05 2001-10-11 University Of Texas System, The APAF-1, the CED-4 human homolog, an activator of caspase-3
EP2083079A1 (fr) 1997-06-18 2009-07-29 Genentech, Inc. Apo-2DcR
US6342220B1 (en) 1997-08-25 2002-01-29 Genentech, Inc. Agonist antibodies
AU762959B2 (en) 1997-09-18 2003-07-10 Genentech Inc. DcR3 polypeptide, A TNFR homolog
CA2305713A1 (fr) 1997-10-10 1999-04-22 Genentech, Inc. Reactifs de fusion d'anticorps monoclonal a chaine unique regulant une transcription in vivo
ATE409225T1 (de) 1997-10-29 2008-10-15 Genentech Inc Durch wnt-1 induzierbare gene
EP1481990B1 (fr) 1997-11-21 2007-06-06 Genentech, Inc. Antigènes apparentés à A33 et leurs utilisations pharmacologiques
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
EP1045906B1 (fr) 1998-01-15 2008-10-15 Genentech, Inc. Apo-2 ligand
US6727079B1 (en) 1998-02-25 2004-04-27 The United States Of America As Represented By The Department Of Health And Human Services cDNA encoding a gene BOG (B5T Over-expressed Gene) and its protein product
EP2050762A3 (fr) 1998-03-10 2009-07-08 Genentech, Inc. Nouvelles polypeptides et acides nucléiques les codant
ES2313778T3 (es) 1998-03-17 2009-03-01 Genentech, Inc. Polipeptidos homologos de vegf y de bmp1.
EP1865061A3 (fr) 1998-05-15 2007-12-19 Genentech, Inc. Polypeptides allogéniques IL-17 et utilisations thérapeutiques
EP3112468A1 (fr) 1998-05-15 2017-01-04 Genentech, Inc. Polypeptides allogéniques il-17 et utilisations thérapeutiques
EP2333069A3 (fr) 1998-05-15 2011-09-14 Genentech, Inc. Utilisations therapeutiques de polypeptides homologues de il-17
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
EP1820859B9 (fr) 1998-12-22 2009-10-28 Genentech, Inc. Procédés et compositions d'inhibition de la croissance de cellules néoplasiques
EP1141299A2 (fr) 1998-12-23 2001-10-10 Genentech, Inc. Polypeptides apparentes a il-1
EP1953173B1 (fr) 1999-06-15 2009-11-18 Genentech, Inc. Polypeptides sécrétés et transmembranaires, et acides nucléiques les codant
EP1222209A2 (fr) 1999-10-20 2002-07-17 Genentech, Inc. Recepteur tccr de cytokine de type i
EP1666495A1 (fr) 1999-12-01 2006-06-07 Genentech, Inc. Polypeptides secretés et transmembranaires et acides nucléiques les codant
EP2258848B1 (fr) 1999-12-23 2014-03-05 Genentech, Inc. Polypeptides allogéniques IL-17 et utilisations thérapeutiques
DE60017942T2 (de) 1999-12-30 2006-05-18 Genencor International, Inc., Palo Alto Trichoderma reesei xylanase
EP1246917B1 (fr) 2000-01-13 2009-03-04 Genentech, Inc. Polypeptides humains stra6
ATE343562T1 (de) 2000-03-23 2006-11-15 Elan Pharm Inc Verbindungen und verfahren zur behandlung der alzheimerschen krankheit
DK1266018T3 (da) 2000-03-24 2008-09-01 Genencor Int Fremstilling af udskilte proteiner af rekombinante, eukaryotiske celler
CA2709771A1 (fr) 2000-06-23 2002-01-03 Genentech, Inc. Compositions et methode de diagnostic et de traitement des troubles mettant en cause l'angiogenese
DK2042597T3 (da) 2000-06-23 2014-08-11 Genentech Inc Sammensætninger og fremgangsmåder til diagnose og behandling af sygdomme, der involverer angiogenese
ATE412009T1 (de) 2000-08-24 2008-11-15 Genentech Inc Methode zur inhibierung von il-22 induziertem pap1
EP1944317A3 (fr) 2000-09-01 2008-09-17 Genentech, Inc. Polypeptides sécrétés et transmembranaires, et acides nucléiques les codant
US6645767B1 (en) 2000-10-03 2003-11-11 Carnegie Mellon University Cells engineered to contain genes of interest without expressed bacterial sequences and materials and methods therefor
US6673580B2 (en) 2000-10-27 2004-01-06 Genentech, Inc. Identification and modification of immunodominant epitopes in polypeptides
US20070160576A1 (en) 2001-06-05 2007-07-12 Genentech, Inc. IL-17A/F heterologous polypeptides and therapeutic uses thereof
ES2372321T3 (es) 2001-06-20 2012-01-18 Genentech, Inc. Composiciones y métodos para el diagnóstico y tratamiento de un tumor de pulmón.
NZ530985A (en) 2001-08-29 2006-03-31 Genentech Inc Bv8 nucleic acids and polypeptides with mitogenic activity
KR101008758B1 (ko) 2001-09-18 2011-01-14 제넨테크, 인크. 종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
KR100623128B1 (ko) 2002-01-02 2006-09-14 제넨테크, 인크. 종양의 진단 및 치료 방법 및 이를 위한 조성물
CA2476518A1 (fr) 2002-02-22 2003-09-04 Genentech, Inc. Compositions et methodes de traitement de maladies relatives au systeme immunitaire
EP2011886A3 (fr) 2002-04-16 2009-02-11 Genentech, Inc. Compositions et procédés pour le traitement et le diagnostic d'une tumeur
EP2305710A3 (fr) 2002-06-03 2013-05-29 Genentech, Inc. Bibliothèques de phages et anticorps synthétiques
AU2003243400B2 (en) 2002-06-07 2009-10-29 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2004004649A2 (fr) 2002-07-08 2004-01-15 Genentech, Inc. Compositions et procedes destines au traitement de maladies liees au systeme immunitaire
WO2007068784A1 (fr) 2005-12-14 2007-06-21 Licentia Ltd Nouveau facteur neurotrophique et utilisations de celui-ci
EP1539228B1 (fr) 2002-09-11 2010-12-29 Genentech, Inc. Nouvelles composition et methodes servant au traitement de maladies associees au systeme immunitaire
CA2497334A1 (fr) 2002-09-11 2004-03-25 Genentech, Inc. Nouvelles compositions et methodes pour le traitement de maladies associees au systeme immunitaire
JP2006515165A (ja) 2002-09-16 2006-05-25 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための新規組成物と方法
JP2006513700A (ja) 2002-09-25 2006-04-27 ジェネンテック・インコーポレーテッド 乾癬の治療のための新規組成物と方法
EP1576137A4 (fr) 2002-10-29 2010-06-30 Genentech Inc Compositions et methodes de traitement de maladies liees au systeme immunitaire
EP2364716A3 (fr) 2002-11-08 2012-01-11 Genentech, Inc. Compositions et procédés pour le traitement des maladies liées aux cellules tueuses naturelles
AU2003302386B2 (en) 2002-11-26 2010-04-01 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
EP2526960A1 (fr) 2003-03-12 2012-11-28 Genentech, Inc. Utilisation de BV8 et/ou de EG-VEGF pour promouvoir l'hématopoièse
ZA200507757B (en) 2003-04-04 2007-01-31 Genentech Inc High concentration antibody and protein formulations
MXPA05013565A (es) 2003-06-12 2006-03-09 Lilly Co Eli Proteinas de fusion analogas al glp-1.
US7097993B2 (en) 2003-06-25 2006-08-29 Wisconsin Alumni Research Foundation Method for identifying an agent that modulates type 1 phosphatidylinositol phosphate kinase isoform β661 activity
NZ544317A (en) 2003-07-08 2009-05-31 Genentech Inc IL-17 A/F heterologous polypeptides and therapeutic uses thereof
WO2005019258A2 (fr) 2003-08-11 2005-03-03 Genentech, Inc. Compositions et methodes de traitement de maladies relatives au systeme immunitaire
ES2472690T3 (es) 2003-11-17 2014-07-02 Genentech, Inc. Anticuerpo contra CD22 para el tratamiento de tumores de origen hematopoy�tico
ATE502298T1 (de) 2003-12-19 2011-04-15 Univ California Verfahren und materialien zur beurteilung von prostatakrebstherapien
NZ550102A (en) 2004-02-24 2010-10-29 Univ California Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives)
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
NZ563341A (en) 2005-06-06 2009-10-30 Genentech Inc Methods for identifying agents that modulate a gene that encodes for a PRO1568 polypeptide
JP2009504183A (ja) 2005-08-15 2009-02-05 ジェネンテック・インコーポレーテッド 遺伝子破壊、それに関連する組成物および方法
CN101292036B (zh) 2005-10-21 2016-04-13 弗·哈夫曼-拉罗切有限公司 用于重组表达多肽的方法
WO2007081608A2 (fr) 2005-11-21 2007-07-19 Genentech, Inc. Nouvelles dissociations de gènes, compositions et procédés les concernant
US20080311107A1 (en) 2006-02-17 2008-12-18 Genetech, Inc. Novel Gene Disruptions, Compositions and Methods Relating Thereto
EP2004181B3 (fr) 2006-03-27 2023-05-24 The Regents Of The University Of California Modulateur de récepteur androgène pour le traitement du cancer de la prostate et de maladies associées au récepteur androgène
US8110594B2 (en) 2006-03-29 2012-02-07 The Regents Of The University Of California Diarylthiohydantoin compounds
WO2007126455A2 (fr) 2006-04-05 2007-11-08 Genentech, Inc. Méthode d'utilisation du boc/cdo pour moduler l'émission des signaux du hedgehog
US20090288176A1 (en) 2006-04-19 2009-11-19 Genentech, Inc. Novel Gene Disruptions, Compositions and Methods Relating Thereto
EP2078040B1 (fr) 2006-11-02 2017-06-28 Daniel J. Capon Procédé de production de polypeptides hybrides présentant des parties mobiles
ES2379413T3 (es) 2007-02-22 2012-04-25 Genentech, Inc. Procedimientos para detectar la enfermedad inflamatoria del intestino
JP2010533495A (ja) 2007-07-16 2010-10-28 ジェネンテック, インコーポレイテッド ヒト化CD79b抗体およびイムノコンジュゲートならびにそれらの使用
PT2176296E (pt) 2007-07-16 2012-05-14 Genentech Inc Anticorpos e imunoconjugados anti-cd79b e métodos de utilização
CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术(上海)有限公司 白介素-22在治疗脂肪肝中的应用
TR201816045T4 (tr) 2007-10-12 2018-11-21 Hoffmann La Roche Birden fazla nükleik asitten protein ekspresyonu.
CA2966280A1 (fr) 2007-10-26 2009-04-30 The Regents Of The University Of California Composes de diaryl-hydantoine
MY157403A (en) 2008-01-31 2016-06-15 Genentech Inc Anti-cd79b antibodies and immunoconjugates and methods of use
US20090258013A1 (en) 2008-04-09 2009-10-15 Genentech, Inc. Novel compositions and methods for the treatment of immune related diseases
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
FI20080326A0 (fi) 2008-04-30 2008-04-30 Licentia Oy Neurotroofinen tekijä MANF ja sen käytöt
JP6132548B2 (ja) 2009-04-01 2017-05-24 ジェネンテック, インコーポレイテッド 抗FcRH5抗体および免疫接合体および使用方法
JP6016636B2 (ja) 2009-10-15 2016-10-26 ジェネンテック, インコーポレイテッド 改変したレセプター特異性を持つキメラ線維芽細胞増殖因子
ES2564207T3 (es) 2009-10-22 2016-03-18 F. Hoffmann-La Roche Ag Métodos y composiciones para modular la activación con hepsina de la proteína estimuladora de macrófagos
WO2011056497A1 (fr) 2009-10-26 2011-05-12 Genentech, Inc. Compositions de récepteur de l'activine de type iib et leurs méthodes d'utilisation
WO2011056494A1 (fr) 2009-10-26 2011-05-12 Genentech, Inc. Combinaisons d'antagonistes de la kinase-1 du type récepteur de l'activine et d'antagonistes vegfr3
WO2011056502A1 (fr) 2009-10-26 2011-05-12 Genentech, Inc. Compositions du gene recepteur de proteine morphogenetique osseuse type ii et procedes d'utilisation
KR20120103587A (ko) 2009-11-12 2012-09-19 제넨테크, 인크. 수상돌기 소극 밀도를 증진시키는 방법
EP3002297B1 (fr) 2009-11-30 2020-04-08 F. Hoffmann-La Roche AG Anticorps pour le traitement et la diagnose du tumeurs exprimant slc34a2 ( tat211 )
CN106983749A (zh) 2010-02-16 2017-07-28 亚拉冈制药公司 雄激素受体调节剂及其用途
KR20130004579A (ko) 2010-02-23 2013-01-11 제넨테크, 인크. 종양의 진단 및 치료를 위한 조성물 및 방법
RU2636461C2 (ru) 2010-05-03 2017-11-23 Дженентек, Инк. Композиции и способы для диагностики и лечения опухоли
US8853150B2 (en) 2010-07-29 2014-10-07 Eleven Biotherapeutics, Inc. Chimeric IL-1 receptor type I antagonists
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术(上海)有限公司 白介素-22在治疗病毒性肝炎中的应用
AU2011302522A1 (en) 2010-09-15 2013-05-02 Aligna Technologies, Inc. Bioproduction of aromatic chemicals from lignin-derived compounds
WO2012103240A2 (fr) 2011-01-25 2012-08-02 Eleven Biotherapeutics, Inc. Agents de liaison à un récepteur
SG10201606218WA (en) 2011-07-29 2016-09-29 Eleven Biotherapeutics Inc Purified Proteins
US20140315252A1 (en) 2011-11-23 2014-10-23 Hoffmann-La Roche Inc. Cd40l expressing mammalian cells and their use
CA2865676C (fr) 2012-04-17 2020-03-10 Stefan Klostermann Procede d'expression de polypeptides faisant appel a des acides nucleiques modifies
ES2836424T3 (es) 2012-09-26 2021-06-25 Aragon Pharmaceuticals Inc Antiandrógenos para tratar el cáncer de próstata no metastásico y resistente a la castración
CN104870637A (zh) 2012-12-07 2015-08-26 丹尼斯科美国公司 组合物及使用方法
US20160186221A1 (en) 2012-12-07 2016-06-30 Danisco Us Inc. Compositions and methods of use
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
BR112015022587A2 (pt) 2013-03-13 2017-10-24 Eleven Biotherapeutics Inc formulações de citocina quimérica para entrega ocular
CA2903587C (fr) 2013-03-15 2021-09-28 Genentech, Inc. Polypeptides d'il-22 et proteines de fusion fc il-22 et leurs procedes d'utilisation
EP2968495B1 (fr) 2013-03-15 2019-07-03 Daniel J. Capon Immunoglobuline hybride contenant une liaison non peptidique
US20160075766A1 (en) 2013-05-21 2016-03-17 Roche Diagnostics Operations, Inc. Method for producing antibodies using ovine b-cells and uses thereof
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术(上海)有限公司 Il-22二聚体在制备静脉注射药物中的应用
NZ724904A (en) 2014-03-14 2023-04-28 Biomolecular Holdings Llc Hybrid immunoglobulin containing non-peptidyl linkage
EP3201331A1 (fr) 2014-09-30 2017-08-09 Danisco US Inc. Compositions comprenant de la bêta-mannamase, et procédés d'utilisation
WO2016054185A1 (fr) 2014-09-30 2016-04-07 Danisco Us Inc Compositions comprenant une bêta-mannanase et leurs procédés d'utilisation
EP3201332A1 (fr) 2014-09-30 2017-08-09 Danisco US Inc. Compositions comprenant la bêta-mannanase et procédés d'utilisation
WO2016054194A1 (fr) 2014-09-30 2016-04-07 1/1Danisco Us Inc Compositions comprenant une bêta-mannanase et leurs procédés d'utilisation
WO2016054205A1 (fr) 2014-09-30 2016-04-07 Danisco Us Inc Compositions comprenant de la bêta-mannanase et procédés d'utilisation
CN106413739B (zh) 2014-12-09 2019-09-17 张文涛 Nbp158及其用途
EP3234118A1 (fr) 2014-12-18 2017-10-25 Danisco US Inc. Enzymes multifonctionnelles modifiées par génie génétique et procédés d'utilisation
EP3234119A1 (fr) 2014-12-18 2017-10-25 Danisco US Inc. Enzymes multifonctionnelles modifiées et procédés d'utilisation
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
PL3436571T3 (pl) 2016-03-30 2023-09-25 F. Hoffmann-La Roche Ag Sposób hodowli limfocytów B
WO2017181143A1 (fr) 2016-04-15 2017-10-19 Generon (Shanghai) Corporation, Ltd. Utilisation d'il-22 pour le traitement de l'entérocolite nécrosante
AU2017370682A1 (en) 2016-12-06 2019-06-20 Kaleido Biosciences, Inc. Glycan polymers and related methods thereof
EP3562936B1 (fr) 2017-01-02 2024-05-22 F. Hoffmann-La Roche AG Procédé de culture de lymphocyte b
WO2018152496A1 (fr) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Compositions et méthodes de diagnostic et de traitement de l'infection par le virus zika
EP3615569A1 (fr) 2017-04-25 2020-03-04 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Anticorps et procédés de diagnostic et de traitement d'infection par le virus d'epstein barr
WO2018210896A1 (fr) 2017-05-19 2018-11-22 F. Hoffmann-La Roche Ag Procédé de production d'un surnageant thymocytaire
EP3655430A1 (fr) 2017-07-19 2020-05-27 The U.S.A. as represented by the Secretary, Department of Health and Human Services Anticorps et procédés de diagnostic et de traitement d'infection par le virus de l'hépatite b
JOP20200076A1 (ar) 2017-10-16 2020-04-30 Aragon Pharmaceuticals Inc مضادات أندروجين لعلاج سرطان البروستاتا غير النقيلي المقاوم للاستئصال
RS63812B1 (sr) 2018-01-26 2023-01-31 Hoffmann La Roche Il-22 fc kompozicije i postupci primene
EP3743437A1 (fr) 2018-01-26 2020-12-02 F. Hoffmann-La Roche AG Protéines de fusion il-22 fc et procédés d'utilisation
WO2019165140A1 (fr) 2018-02-21 2019-08-29 Genentech, Inc. Posologie pour un traitement avec des protéines de fusion il-22 fc
US20210171610A1 (en) 2018-05-02 2021-06-10 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
JP2022538178A (ja) 2019-06-28 2022-08-31 エフ.ホフマン-ラ ロシュ アーゲー 抗体の製造方法
WO2021207662A1 (fr) 2020-04-10 2021-10-14 Genentech, Inc. Utilisation d'il-22-fc pour le traitement ou la prévention de la pneumonie, du syndrome de détresse respiratoire aiguë ou du syndrome de libération de cytokines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL76190A0 (en) * 1984-08-31 1985-12-31 Smithkline Beckman Corp Recombinant saccharomyces

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DK417789D0 (da) 1989-08-24
EP0362179A3 (fr) 1990-07-11
EP0362179A2 (fr) 1990-04-04

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