DE602005023550D1 - Verwendungen eines neurotrophischen Faktors - Google Patents

Verwendungen eines neurotrophischen Faktors

Info

Publication number
DE602005023550D1
DE602005023550D1 DE200560023550 DE602005023550T DE602005023550D1 DE 602005023550 D1 DE602005023550 D1 DE 602005023550D1 DE 200560023550 DE200560023550 DE 200560023550 DE 602005023550 T DE602005023550 T DE 602005023550T DE 602005023550 D1 DE602005023550 D1 DE 602005023550D1
Authority
DE
Germany
Prior art keywords
disease
patient
neurotrophic factor
condition
parkinson
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE200560023550
Other languages
English (en)
Inventor
Mart Saarma
Juha Lauren
Paeivi Lindholm
Tonis Timmusk
Raimo Tuominen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HERMO PHARMA LTD., HELSINKI, FI
Original Assignee
Licentia Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Licentia Oy filed Critical Licentia Oy
Publication of DE602005023550D1 publication Critical patent/DE602005023550D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/035Animal model for multifactorial diseases
    • A01K2267/0356Animal model for processes and diseases of the central nervous system, e.g. stress, learning, schizophrenia, pain, epilepsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE200560023550 2005-12-14 2005-12-14 Verwendungen eines neurotrophischen Faktors Active DE602005023550D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/FI2005/050461 WO2007068784A1 (en) 2005-12-14 2005-12-14 Novel neurotrophic factor protein and uses thereof

Publications (1)

Publication Number Publication Date
DE602005023550D1 true DE602005023550D1 (de) 2010-10-21

Family

ID=38162600

Family Applications (1)

Application Number Title Priority Date Filing Date
DE200560023550 Active DE602005023550D1 (de) 2005-12-14 2005-12-14 Verwendungen eines neurotrophischen Faktors

Country Status (11)

Country Link
US (4) US20100285045A1 (de)
EP (2) EP1969003B8 (de)
JP (1) JP5236488B2 (de)
AT (1) ATE480559T1 (de)
AU (1) AU2005339101B2 (de)
CA (1) CA2633468C (de)
DE (1) DE602005023550D1 (de)
DK (1) DK1969003T3 (de)
ES (1) ES2352205T3 (de)
PL (1) PL1969003T3 (de)
WO (2) WO2007068784A1 (de)

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FI20080326A0 (fi) 2008-04-30 2008-04-30 Licentia Oy Neurotroofinen tekijä MANF ja sen käytöt
CN103987400B (zh) * 2011-06-09 2019-09-13 迈阿密大学 治疗视网膜疾病的方法
FI20115870A0 (fi) * 2011-09-05 2011-09-05 Urmas Arumaee Neuroprotektiiviset soluihin tunkeutuvat peptidit
US20130331330A1 (en) * 2012-06-08 2013-12-12 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating alzheimer's disease and other tauopathies with inhibitors of microtubule affinity regulating kinase
DK3063168T3 (en) 2013-10-30 2019-04-15 Univ Western Australia NEURO PROTECTIVE PEPTIDES
US20170252403A1 (en) * 2014-10-06 2017-09-07 Amarantus Bioscience Holdings, Inc. Methods and compositions for treating retinal disorders
JP7201432B2 (ja) 2015-11-18 2023-01-10 ヘランティス ファーマ ピーエルシー 中枢神経系疾患の鼻腔内治療に使用するためのcdnfまたはmanfを含む組成物
RU2019136495A (ru) 2017-05-04 2021-06-04 Хельсингин Илиописто C-концевые фрагменты cdnf и маnf, фармацевтические композиции, содержащие указанные фрагменты, и применения указанных фрагментов и композиций
US11614450B2 (en) * 2017-06-02 2023-03-28 Peter Dominiek Emiel Maria Verhaert Mass spectrometry histochemistry of peptides from formaldehyde-fixed, paraffin-embedded tissue
RU2020131433A (ru) 2018-03-29 2022-05-04 Хельсингин Илиописто C-концевые фрагменты cdnf, фармацевтические композиции, содержащие указанные фрагменты, и применения указанных фрагментов и композиций
CN108925783B (zh) * 2018-07-23 2021-09-21 浙江大学 烟粉虱manf基因或其表达的蛋白作为靶点在制备防治烟粉虱的药物中的应用
EP3838912A1 (de) 2019-12-20 2021-06-23 Herantis Pharma Oyj Retro-inverso peptide
EP3838345A1 (de) 2019-12-20 2021-06-23 Herantis Pharma Oyj Makrocyclische peptide
WO2023202835A1 (en) * 2022-04-21 2023-10-26 Instituto de Medicina Molecular João Lobo Antunes Mesencephalic astrocyte-derived neurotrophic factor (manf) for increasing muscle regeneration

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Also Published As

Publication number Publication date
WO2007068784A1 (en) 2007-06-21
WO2007068803A1 (en) 2007-06-21
PL1969003T3 (pl) 2011-05-31
EP1960426B1 (de) 2014-04-02
DK1969003T3 (da) 2010-12-13
AU2005339101B2 (en) 2013-01-10
EP1960426A4 (de) 2009-07-08
EP1969003B8 (de) 2010-11-10
JP5236488B2 (ja) 2013-07-17
EP1969003A1 (de) 2008-09-17
ATE480559T1 (de) 2010-09-15
US20110251132A1 (en) 2011-10-13
US9127082B2 (en) 2015-09-08
ES2352205T3 (es) 2011-02-16
US20190153052A1 (en) 2019-05-23
EP1969003B1 (de) 2010-09-08
CA2633468C (en) 2014-02-18
JP2009519028A (ja) 2009-05-14
AU2005339101A1 (en) 2007-06-21
US8980821B2 (en) 2015-03-17
US20100285045A1 (en) 2010-11-11
CA2633468A1 (en) 2007-06-21
EP1969003A4 (de) 2009-03-25
EP1960426A1 (de) 2008-08-27
US20080269154A1 (en) 2008-10-30

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