DK41584A - Optisk aktive bicycliske imino-alfa-carboxylsyreestere, fremgangsmaade til adskillelse af racemiske blandinger deraf samt anvendelse af de saaledes opnaaede forbindelser til syntese af carboxyalkyldipeptider - Google Patents
Optisk aktive bicycliske imino-alfa-carboxylsyreestere, fremgangsmaade til adskillelse af racemiske blandinger deraf samt anvendelse af de saaledes opnaaede forbindelser til syntese af carboxyalkyldipeptider Download PDFInfo
- Publication number
- DK41584A DK41584A DK41584A DK41584A DK41584A DK 41584 A DK41584 A DK 41584A DK 41584 A DK41584 A DK 41584A DK 41584 A DK41584 A DK 41584A DK 41584 A DK41584 A DK 41584A
- Authority
- DK
- Denmark
- Prior art keywords
- carboxylypty
- alfa
- procedures
- synthesis
- acid esters
- Prior art date
Links
- -1 CARBOXYL Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3303112 | 1983-01-31 | ||
| DE3303139 | 1983-01-31 | ||
| DE19833303139 DE3303139A1 (de) | 1983-01-31 | 1983-01-31 | Verfahren zur herstellung von carboxyalkyldipeptiden |
| DE19833303112 DE3303112A1 (de) | 1983-01-31 | 1983-01-31 | Verfahren zur racemattrennung optisch aktiver bicyclischer imino-(alpha)-carbonsaeuren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK41584D0 DK41584D0 (da) | 1984-01-30 |
| DK41584A true DK41584A (da) | 1984-08-01 |
| DK174386B1 DK174386B1 (da) | 2003-01-27 |
Family
ID=25807929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198400415A DK174386B1 (da) | 1983-01-31 | 1984-01-30 | Bicycliske imino-alfa-carboxylsyreestere, fremgangsmåde til deres fremstilling ved adskillelse af racemiske blandinger deraf, eventuelt i form af deres hydrochlorid- eller tosylatsalt samt diastereomert salt i form af en beskyttet N-acyleret, ...... |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0115345B1 (da) |
| JP (1) | JPH0788358B2 (da) |
| KR (1) | KR910001438B1 (da) |
| AU (1) | AU566589B2 (da) |
| CA (2) | CA1283249C (da) |
| DE (1) | DE3468415D1 (da) |
| DK (1) | DK174386B1 (da) |
| ES (2) | ES529272A0 (da) |
| FI (1) | FI88153C (da) |
| GR (1) | GR82650B (da) |
| HU (1) | HU191120B (da) |
| IE (1) | IE56654B1 (da) |
| IL (1) | IL70830A (da) |
| MA (1) | MA20020A1 (da) |
| NO (1) | NO166641C (da) |
| NZ (1) | NZ206980A (da) |
| PT (1) | PT78036B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4500713A (en) * | 1982-09-23 | 1985-02-19 | Usv Pharmaceutical Corporation | Therapeutic dipeptides |
| DE3345355A1 (de) * | 1983-12-15 | 1985-06-27 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester |
| ZA855659B (en) * | 1984-07-30 | 1987-03-25 | Schering Corp | Novel process for the preparation of cis,endo-octahydrocyclopenta(b)pyrrole-2-carboxylate |
| HU192914B (en) * | 1985-02-11 | 1987-07-28 | Richter Gedeon Vegyeszet | Process for producing new 3-/substituted amino/-5-phenyl-2/3h/-furanone derivatives and pharmaceutically acceptable salts |
| FR2620703B1 (fr) * | 1987-09-17 | 1991-10-04 | Adir | Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides |
| HU904967D0 (en) * | 1988-04-22 | 1991-01-28 | Hoechst Ag | Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives |
| US6407262B1 (en) | 2001-11-21 | 2002-06-18 | Brantford Chemicals Inc. | Process for the preparation of Ramipril |
| WO2006059347A2 (en) * | 2004-12-01 | 2006-06-08 | Morepen Laboratories Limited | Improved process for preparation of ramipril |
| US8558023B2 (en) | 2010-04-20 | 2013-10-15 | Chiral Quest, Inc. | Enantioselective process for cycloalkenyl β-substituted alanines |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2503155A2 (fr) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
| IE52663B1 (en) * | 1980-04-02 | 1988-01-20 | Warner Lambert Co | Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids |
| US4374847A (en) * | 1980-10-27 | 1983-02-22 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
-
1984
- 1984-01-25 HU HU84312A patent/HU191120B/hu unknown
- 1984-01-27 DE DE8484100858T patent/DE3468415D1/de not_active Expired
- 1984-01-27 FI FI840350A patent/FI88153C/fi not_active IP Right Cessation
- 1984-01-27 EP EP84100858A patent/EP0115345B1/de not_active Expired
- 1984-01-28 KR KR1019840000396A patent/KR910001438B1/ko not_active Expired
- 1984-01-30 NZ NZ206980A patent/NZ206980A/en unknown
- 1984-01-30 MA MA20241A patent/MA20020A1/fr unknown
- 1984-01-30 GR GR73651A patent/GR82650B/el unknown
- 1984-01-30 DK DK198400415A patent/DK174386B1/da not_active IP Right Cessation
- 1984-01-30 NO NO840350A patent/NO166641C/no not_active IP Right Cessation
- 1984-01-30 ES ES529272A patent/ES529272A0/es active Granted
- 1984-01-30 CA CA000446349A patent/CA1283249C/en not_active Expired - Lifetime
- 1984-01-30 IL IL70830A patent/IL70830A/xx not_active IP Right Cessation
- 1984-01-30 PT PT78036A patent/PT78036B/pt unknown
- 1984-01-30 IE IE210/84A patent/IE56654B1/en not_active IP Right Cessation
- 1984-01-31 AU AU23933/84A patent/AU566589B2/en not_active Expired
- 1984-04-04 ES ES531284A patent/ES531284A0/es active Granted
-
1988
- 1988-09-06 CA CA000576609A patent/CA1317067C/en not_active Expired - Lifetime
-
1991
- 1991-01-30 JP JP3027801A patent/JPH0788358B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR910001438B1 (ko) | 1991-03-07 |
| AU2393384A (en) | 1984-08-02 |
| NO840350L (no) | 1984-08-01 |
| NO166641C (no) | 1991-08-21 |
| FI88153C (fi) | 1993-04-13 |
| DE3468415D1 (en) | 1988-02-11 |
| IE840210L (en) | 1984-07-31 |
| IE56654B1 (en) | 1991-10-23 |
| DK174386B1 (da) | 2003-01-27 |
| AU566589B2 (en) | 1987-10-22 |
| EP0115345B1 (de) | 1988-01-07 |
| NO166641B (no) | 1991-05-13 |
| ES8500228A1 (es) | 1984-10-01 |
| PT78036B (de) | 1986-05-30 |
| JPH0788358B2 (ja) | 1995-09-27 |
| HU191120B (en) | 1987-01-28 |
| DK41584D0 (da) | 1984-01-30 |
| GR82650B (da) | 1985-02-07 |
| IL70830A (en) | 1988-02-29 |
| ES8501759A1 (es) | 1984-12-01 |
| CA1317067C (en) | 1993-04-27 |
| NZ206980A (en) | 1988-05-30 |
| HUT34159A (en) | 1985-02-28 |
| ES529272A0 (es) | 1984-10-01 |
| IL70830A0 (en) | 1984-04-30 |
| EP0115345A1 (de) | 1984-08-08 |
| FI840350A0 (fi) | 1984-01-27 |
| FI840350A7 (fi) | 1984-08-01 |
| CA1283249C (en) | 1991-04-16 |
| JPH0517439A (ja) | 1993-01-26 |
| MA20020A1 (fr) | 1984-10-01 |
| FI88153B (fi) | 1992-12-31 |
| PT78036A (de) | 1984-02-01 |
| ES531284A0 (es) | 1984-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |