AU2393384A - Resolution of optical isomers of bicycle pyrrollidine compounds and the products in peptide synthesis - Google Patents
Resolution of optical isomers of bicycle pyrrollidine compounds and the products in peptide synthesisInfo
- Publication number
- AU2393384A AU2393384A AU23933/84A AU2393384A AU2393384A AU 2393384 A AU2393384 A AU 2393384A AU 23933/84 A AU23933/84 A AU 23933/84A AU 2393384 A AU2393384 A AU 2393384A AU 2393384 A AU2393384 A AU 2393384A
- Authority
- AU
- Australia
- Prior art keywords
- pyrrollidine
- bicycle
- resolution
- compounds
- products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3303139 | 1983-01-31 | ||
| DE19833303112 DE3303112A1 (en) | 1983-01-31 | 1983-01-31 | METHOD FOR RACEMATE SEPARATION OF OPTICALLY ACTIVE BICYCLIC IMINO (ALPHA) CARBONIC ACIDS |
| DE19833303139 DE3303139A1 (en) | 1983-01-31 | 1983-01-31 | Process for the preparation of carboxyalkyldipeptides |
| DE3303112 | 1983-01-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2393384A true AU2393384A (en) | 1984-08-02 |
| AU566589B2 AU566589B2 (en) | 1987-10-22 |
Family
ID=25807929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU23933/84A Expired AU566589B2 (en) | 1983-01-31 | 1984-01-31 | Resolution of optical isomers of bicycle pyrrollidine compounds and the products in peptide synthesis |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0115345B1 (en) |
| JP (1) | JPH0788358B2 (en) |
| KR (1) | KR910001438B1 (en) |
| AU (1) | AU566589B2 (en) |
| CA (2) | CA1283249C (en) |
| DE (1) | DE3468415D1 (en) |
| DK (1) | DK174386B1 (en) |
| ES (2) | ES529272A0 (en) |
| FI (1) | FI88153C (en) |
| GR (1) | GR82650B (en) |
| HU (1) | HU191120B (en) |
| IE (1) | IE56654B1 (en) |
| IL (1) | IL70830A (en) |
| MA (1) | MA20020A1 (en) |
| NO (1) | NO166641C (en) |
| NZ (1) | NZ206980A (en) |
| PT (1) | PT78036B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4500713A (en) * | 1982-09-23 | 1985-02-19 | Usv Pharmaceutical Corporation | Therapeutic dipeptides |
| DE3345355A1 (en) * | 1983-12-15 | 1985-06-27 | Hoechst Ag, 6230 Frankfurt | METHOD FOR RACEMATE CLEAVING BICYCLIC IMINO (ALPHA) CARBONIC ACID ESTERS |
| CA1244041A (en) * | 1984-07-30 | 1988-11-01 | Elijah H. Gold | Process for the preparation of cis, endo- octahydrocyclopenta¬b|pyrrole-2-carboxylate |
| HU192914B (en) * | 1985-02-11 | 1987-07-28 | Richter Gedeon Vegyeszet | Process for producing new 3-/substituted amino/-5-phenyl-2/3h/-furanone derivatives and pharmaceutically acceptable salts |
| FR2620703B1 (en) * | 1987-09-17 | 1991-10-04 | Adir | PROCESS FOR THE INDUSTRIAL SYNTHESIS OF PERHYDROINDOLE CARBOXYLIC ACID - 2 (2S, 3AS, 7AS). APPLICATION TO THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES |
| HU904967D0 (en) * | 1988-04-22 | 1991-01-28 | Hoechst Ag | Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives |
| US6407262B1 (en) | 2001-11-21 | 2002-06-18 | Brantford Chemicals Inc. | Process for the preparation of Ramipril |
| WO2006059347A2 (en) * | 2004-12-01 | 2006-06-08 | Morepen Laboratories Limited | Improved process for preparation of ramipril |
| ES2686298T3 (en) | 2010-04-20 | 2018-10-17 | Chiral Quest, Inc. | Enantioselective procedure for cycloalkenyl substituted beta alanines |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2503155A2 (en) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | NOVEL SUBSTITUTED IMINO DIACIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS AN ENZYME INHIBITOR |
| IE52663B1 (en) * | 1980-04-02 | 1988-01-20 | Warner Lambert Co | Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids |
| US4374847A (en) * | 1980-10-27 | 1983-02-22 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
-
1984
- 1984-01-25 HU HU84312A patent/HU191120B/en unknown
- 1984-01-27 EP EP84100858A patent/EP0115345B1/en not_active Expired
- 1984-01-27 DE DE8484100858T patent/DE3468415D1/en not_active Expired
- 1984-01-27 FI FI840350A patent/FI88153C/en not_active IP Right Cessation
- 1984-01-28 KR KR1019840000396A patent/KR910001438B1/en not_active IP Right Cessation
- 1984-01-30 IE IE210/84A patent/IE56654B1/en not_active IP Right Cessation
- 1984-01-30 NO NO840350A patent/NO166641C/en not_active IP Right Cessation
- 1984-01-30 ES ES529272A patent/ES529272A0/en active Granted
- 1984-01-30 NZ NZ206980A patent/NZ206980A/en unknown
- 1984-01-30 GR GR73651A patent/GR82650B/el unknown
- 1984-01-30 DK DK198400415A patent/DK174386B1/en not_active IP Right Cessation
- 1984-01-30 PT PT78036A patent/PT78036B/en unknown
- 1984-01-30 MA MA20241A patent/MA20020A1/en unknown
- 1984-01-30 CA CA000446349A patent/CA1283249C/en not_active Expired - Lifetime
- 1984-01-30 IL IL70830A patent/IL70830A/en not_active IP Right Cessation
- 1984-01-31 AU AU23933/84A patent/AU566589B2/en not_active Expired
- 1984-04-04 ES ES531284A patent/ES8501759A1/en not_active Expired
-
1988
- 1988-09-06 CA CA000576609A patent/CA1317067C/en not_active Expired - Lifetime
-
1991
- 1991-01-30 JP JP3027801A patent/JPH0788358B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR910001438B1 (en) | 1991-03-07 |
| FI88153C (en) | 1993-04-13 |
| FI88153B (en) | 1992-12-31 |
| CA1283249C (en) | 1991-04-16 |
| FI840350A0 (en) | 1984-01-27 |
| IL70830A (en) | 1988-02-29 |
| MA20020A1 (en) | 1984-10-01 |
| NZ206980A (en) | 1988-05-30 |
| HUT34159A (en) | 1985-02-28 |
| CA1317067C (en) | 1993-04-27 |
| PT78036A (en) | 1984-02-01 |
| HU191120B (en) | 1987-01-28 |
| ES8500228A1 (en) | 1984-10-01 |
| EP0115345A1 (en) | 1984-08-08 |
| DK41584D0 (en) | 1984-01-30 |
| FI840350A (en) | 1984-08-01 |
| NO166641C (en) | 1991-08-21 |
| DK174386B1 (en) | 2003-01-27 |
| IL70830A0 (en) | 1984-04-30 |
| NO166641B (en) | 1991-05-13 |
| PT78036B (en) | 1986-05-30 |
| DK41584A (en) | 1984-08-01 |
| IE840210L (en) | 1984-07-31 |
| ES531284A0 (en) | 1984-12-01 |
| DE3468415D1 (en) | 1988-02-11 |
| ES8501759A1 (en) | 1984-12-01 |
| AU566589B2 (en) | 1987-10-22 |
| JPH0788358B2 (en) | 1995-09-27 |
| EP0115345B1 (en) | 1988-01-07 |
| NO840350L (en) | 1984-08-01 |
| IE56654B1 (en) | 1991-10-23 |
| ES529272A0 (en) | 1984-10-01 |
| GR82650B (en) | 1985-02-07 |
| JPH0517439A (en) | 1993-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Assignment registered |
Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH Free format text: FORMER OWNER WAS: HOECHST A.G. |
|
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |