DK408186A - Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne - Google Patents

Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne Download PDF

Info

Publication number
DK408186A
DK408186A DK408186A DK408186A DK408186A DK 408186 A DK408186 A DK 408186A DK 408186 A DK408186 A DK 408186A DK 408186 A DK408186 A DK 408186A DK 408186 A DK408186 A DK 408186A
Authority
DK
Denmark
Prior art keywords
podophyllotoxin
derivatives
compounds
pharmaceutical preparations
procedures
Prior art date
Application number
DK408186A
Other languages
English (en)
Other versions
DK169506B1 (da
DK408186D0 (da
Inventor
Boerje Rosen
Kurt Leander
Original Assignee
Conpharm Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conpharm Ab filed Critical Conpharm Ab
Publication of DK408186A publication Critical patent/DK408186A/da
Publication of DK408186D0 publication Critical patent/DK408186D0/da
Application granted granted Critical
Publication of DK169506B1 publication Critical patent/DK169506B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK408186A 1984-12-28 1986-08-27 Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme DK169506B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8406660 1984-12-28
SE8406660 1984-12-28
SE8500541 1985-12-20
PCT/SE1985/000541 WO1986004062A1 (en) 1984-12-28 1985-12-20 Pharmaceutically active compound and a method for its preparation

Publications (3)

Publication Number Publication Date
DK408186A true DK408186A (da) 1986-08-27
DK408186D0 DK408186D0 (da) 1986-08-27
DK169506B1 DK169506B1 (da) 1994-11-14

Family

ID=20358339

Family Applications (1)

Application Number Title Priority Date Filing Date
DK408186A DK169506B1 (da) 1984-12-28 1986-08-27 Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme

Country Status (23)

Country Link
US (1) US4788216A (da)
EP (1) EP0207124B1 (da)
JP (2) JPH0720966B2 (da)
CN (1) CN1006795B (da)
AP (1) AP32A (da)
AT (1) ATE68186T1 (da)
AU (1) AU585936B2 (da)
CA (1) CA1255230A (da)
DE (1) DE3584370D1 (da)
DK (1) DK169506B1 (da)
DZ (1) DZ876A1 (da)
EG (1) EG17788A (da)
ES (1) ES8701761A1 (da)
FI (1) FI89330C (da)
GR (1) GR853145B (da)
HU (1) HU201672B (da)
IL (1) IL77456A (da)
MA (1) MA20602A1 (da)
NO (1) NO863329D0 (da)
PT (1) PT81760B (da)
TN (1) TNSN86004A1 (da)
WO (1) WO1986004062A1 (da)
ZA (1) ZA859881B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
EP0461141B1 (en) * 1989-02-23 1999-11-03 University Of North Carolina At Chapel Hill Etoposide analogues
SE464167B (sv) 1989-07-31 1991-03-18 Analytecon Sa Topisk farmaceutisk beredning av podophyllotoxin
US5332811A (en) * 1989-09-12 1994-07-26 The University Of North Carolina At Chapel Hill Etopside analogs
US5338867A (en) * 1992-04-24 1994-08-16 Genelabs Technologies, Inc. Preparation of 4β- amino podophyllotoxin compounds
SE9301831D0 (sv) * 1993-05-28 1993-05-28 Analytecon S A Pharmaceutical compositions
GB9422947D0 (en) * 1994-11-14 1995-01-04 Univ Salamanca Immunosuppressive cyclolignan derivatives
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
FI105152B (fi) * 1998-07-17 2000-06-30 Eero Saarela Paikallinen kivunlievitysmenetelmä
US6143304A (en) * 1999-08-17 2000-11-07 The University Of Mississippi Enhanced yield of podophyllotoxin from natural products through in situ conversion methods
SE0102168D0 (sv) 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
DE60233601D1 (de) * 2001-06-19 2009-10-15 Axelar Ab Verwendung von bestimmten Cyclolignanen
SE0203746D0 (sv) * 2002-12-18 2002-12-18 Karolinska Innovations Ab New compounds
AU2009263074A1 (en) * 2008-06-23 2009-12-30 Axelar Ab Use of cyclolignans for the treatment of a hyperactive immune system
WO2013124380A1 (en) * 2012-02-24 2013-08-29 Nestec S.A. Peltatin for the treatment of chronic inflammatory disorders
WO2015028456A1 (en) * 2013-08-28 2015-03-05 Nestec S.A. PPAR modulators
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA635769A (en) * 1962-01-30 Rutschmann Jurg Amides of podophyllic acid and picropodophyllic acid
SE335139B (da) * 1964-08-12 1971-05-17 Sandoz Ag
US4122092A (en) * 1977-08-25 1978-10-24 University Of Rochester Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone
US4567253A (en) * 1984-02-03 1986-01-28 Tony Durst 2-Substituted derivatives of podophyllotoxin and etoposide
GB8424269D0 (en) * 1984-09-26 1984-10-31 Pharma Medica As Isolation and purification of podophyllotoxin

Also Published As

Publication number Publication date
HU201672B (en) 1990-12-28
NO863329L (no) 1986-08-19
JP2572558B2 (ja) 1997-01-16
IL77456A0 (en) 1986-08-31
FI863482A (fi) 1986-08-27
EP0207124B1 (en) 1991-10-09
AU585936B2 (en) 1989-06-29
ATE68186T1 (de) 1991-10-15
FI89330B (fi) 1993-06-15
EG17788A (en) 1990-12-30
ZA859881B (en) 1986-09-24
FI863482A0 (fi) 1986-08-27
DK169506B1 (da) 1994-11-14
ES550504A0 (es) 1986-12-01
ES8701761A1 (es) 1986-12-01
CN85109666A (zh) 1986-10-29
FI89330C (fi) 1993-09-27
JPH07173063A (ja) 1995-07-11
CA1255230A (en) 1989-06-06
AP32A (en) 1988-12-07
AU5300386A (en) 1986-07-29
NO863329D0 (no) 1986-08-19
TNSN86004A1 (fr) 1990-01-01
EP0207124A1 (en) 1987-01-07
GR853145B (da) 1986-04-29
PT81760B (pt) 1987-11-11
CN1006795B (zh) 1990-02-14
PT81760A (en) 1986-01-02
WO1986004062A1 (en) 1986-07-17
MA20602A1 (fr) 1986-07-01
JPH0720966B2 (ja) 1995-03-08
AP8500017A0 (en) 1985-11-01
US4788216A (en) 1988-11-29
DZ876A1 (fr) 2004-09-13
JPS62501360A (ja) 1987-06-04
HUT47582A (en) 1989-03-28
DE3584370D1 (de) 1991-11-14
DK408186D0 (da) 1986-08-27
IL77456A (en) 1989-07-31

Similar Documents

Publication Publication Date Title
DK408186A (da) Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne
DK295287D0 (da) Fremgangsmaade til fremstilling af ravsyre ved anaerob fermentering
NO833346L (no) Fremgangsmaate ved fremstilling av nye diazabicyclo-(3,3,1)-nonaner
ES8404332A1 (es) Procedimiento para preparar acidos omega-(1,4,5-trifenilimidazol-2-iloxi)-alcanicos
AU6319480A (en) 2-hydroxyalkyl-3,4,5-trihydroxypiperidines
ES551204A0 (es) Procedimiento para aislar derivados oxigenados de labdano a partir de coleus forskohlii
ES8400417A1 (es) "procedimiento para la preparacion de esteres carboxilicos de 6-hidroxi-2-benzotiazolsulfonamida".
JPS6442427A (en) Sialidase inhibitor
ES437046A2 (es) Un procedimiento para la preparacion de un concentrado o mezcla de hormonas.
ATE4117T1 (de) Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel.
NO872574L (no) FremgangsmŸte for fremstilling av terapeutisk aktive tetrahydro-benzotiazoler.
ATE19623T1 (de) Verfahren zur herstellung von 1-alpha-hydroxy vitamin d oder 1-alpha hydroxy previtamin d derivaten und previtamin d oder tachysteroladdukten mit geeigneten dienophilen.
IT1143012B (it) Composti 6-aril pirimidinici per il trattamento e la prevenzione di infezioni virali e per stimolare la produzione di interferone
ATE46687T1 (de) Basisch substituierte phenylacetaldehyde, ihre herstellung und diese enthaltende arzneimittel.
IL58828A (en) 3-bromoisoxazole derivatives,the preparation of 1-(3-bromoisoxazol-5-yl)-2-tert.butylaminoethanol and pharmaceutical compositions containing it
DK455487A (da) 13alfa-alkylgonan-delta9(11)-5,10-epoxider og fremgangsmaade til fremstilling deraf
JPS5414983A (en) Tunicamine derivative and its preparation
JPS5420195A (en) Preparation of guanosine-5'-monophosphoric acid
JPS5283411A (en) Preparation of 3,3-dimethyl-4-pentenoic acid and its derivatives
JPS55136283A (en) Novel diterpene derivative
JPS5414951A (en) Preparation of vitamin d derivatives
JPS5519049A (en) Production of coenzyme q
JPS53149911A (en) Preparation of alkoxyalkykidene compounds
JPS5271500A (en) Purification of colesterol
JPS5683500A (en) Novel oligoglycoside and antimycotic

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed