DK4031547T3 - Plasmakallikreininhibitorer og anvendelser deraf - Google Patents

Plasmakallikreininhibitorer og anvendelser deraf Download PDF

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Publication number
DK4031547T3
DK4031547T3 DK20785878.8T DK20785878T DK4031547T3 DK 4031547 T3 DK4031547 T3 DK 4031547T3 DK 20785878 T DK20785878 T DK 20785878T DK 4031547 T3 DK4031547 T3 DK 4031547T3
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DK
Denmark
Prior art keywords
plasma kallikrein
kallikrein inhibitors
inhibitors
plasma
kallikrein
Prior art date
Application number
DK20785878.8T
Other languages
Danish (da)
English (en)
Inventor
Nikolaos Papaioannou
Jeremy Mark Travins
Sarah Jocelyn Fink
John Mark Ellard
Alastair Rae
Original Assignee
Takeda Pharmaceuticals Co
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Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
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Publication of DK4031547T3 publication Critical patent/DK4031547T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK20785878.8T 2019-09-18 2020-09-17 Plasmakallikreininhibitorer og anvendelser deraf DK4031547T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962902353P 2019-09-18 2019-09-18
PCT/US2020/051293 WO2021055621A1 (en) 2019-09-18 2020-09-17 Plasma kallikrein inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
DK4031547T3 true DK4031547T3 (da) 2024-09-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK20785878.8T DK4031547T3 (da) 2019-09-18 2020-09-17 Plasmakallikreininhibitorer og anvendelser deraf

Country Status (10)

Country Link
US (2) US11787796B2 (enExample)
EP (2) EP4477220A3 (enExample)
JP (2) JP7777519B2 (enExample)
CN (1) CN114728962B (enExample)
DK (1) DK4031547T3 (enExample)
ES (1) ES2987744T3 (enExample)
FI (1) FI4031547T3 (enExample)
PL (1) PL4031547T3 (enExample)
PT (1) PT4031547T (enExample)
WO (1) WO2021055621A1 (enExample)

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TW202144331A (zh) * 2020-02-13 2021-12-01 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物
TWI873290B (zh) 2020-02-13 2025-02-21 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物
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Also Published As

Publication number Publication date
PT4031547T (pt) 2024-08-27
CN114728962B (zh) 2025-09-19
PL4031547T3 (pl) 2024-10-07
US12221441B2 (en) 2025-02-11
WO2021055621A1 (en) 2021-03-25
FI4031547T3 (fi) 2024-09-16
US20210078999A1 (en) 2021-03-18
EP4477220A2 (en) 2024-12-18
US20230391773A1 (en) 2023-12-07
ES2987744T3 (es) 2024-11-18
CN114728962A (zh) 2022-07-08
JP2022548696A (ja) 2022-11-21
JP7777519B2 (ja) 2025-11-28
EP4031547B1 (en) 2024-07-17
EP4031547A1 (en) 2022-07-27
US11787796B2 (en) 2023-10-17
JP2025179190A (ja) 2025-12-09
EP4477220A3 (en) 2025-02-26

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