PL4031547T3 - Inhibitory kalikreiny osoczowej i ich zastosowania - Google Patents

Inhibitory kalikreiny osoczowej i ich zastosowania

Info

Publication number
PL4031547T3
PL4031547T3 PL20785878.8T PL20785878T PL4031547T3 PL 4031547 T3 PL4031547 T3 PL 4031547T3 PL 20785878 T PL20785878 T PL 20785878T PL 4031547 T3 PL4031547 T3 PL 4031547T3
Authority
PL
Poland
Prior art keywords
plasma kallikrein
kallikrein inhibitors
inhibitors
plasma
kallikrein
Prior art date
Application number
PL20785878.8T
Other languages
English (en)
Inventor
Nikolaos PAPAIOANNOU
Jeremy Mark Travins
Sarah Jocelyn FINK
John Mark Ellard
Alastair Rae
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of PL4031547T3 publication Critical patent/PL4031547T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL20785878.8T 2019-09-18 2020-09-17 Inhibitory kalikreiny osoczowej i ich zastosowania PL4031547T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962902353P 2019-09-18 2019-09-18
PCT/US2020/051293 WO2021055621A1 (en) 2019-09-18 2020-09-17 Plasma kallikrein inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
PL4031547T3 true PL4031547T3 (pl) 2024-10-07

Family

ID=72717914

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20785878.8T PL4031547T3 (pl) 2019-09-18 2020-09-17 Inhibitory kalikreiny osoczowej i ich zastosowania

Country Status (10)

Country Link
US (2) US11787796B2 (pl)
EP (2) EP4031547B1 (pl)
JP (2) JP7777519B2 (pl)
CN (1) CN114728962B (pl)
DK (1) DK4031547T3 (pl)
ES (1) ES2987744T3 (pl)
FI (1) FI4031547T3 (pl)
PL (1) PL4031547T3 (pl)
PT (1) PT4031547T (pl)
WO (1) WO2021055621A1 (pl)

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TW202144331A (zh) * 2020-02-13 2021-12-01 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物
TWI873290B (zh) 2020-02-13 2025-02-21 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物
CN114262322A (zh) * 2020-09-16 2022-04-01 中国科学院上海有机化学研究所 一类细胞程序性坏死抑制剂及其制备方法和用途
TW202308619A (zh) 2021-05-04 2023-03-01 美商特納亞治療股份有限公司 用於治療代謝疾病和hfpef的hdac6抑制劑
CN114907260A (zh) * 2022-05-27 2022-08-16 河南省科学院高新技术研究中心 一种利用离子液体制备4-溴甲基喹啉酮的方法
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WO2025001956A1 (zh) * 2023-06-30 2025-01-02 远森制药（杭州）有限公司 杂芳族甲酰胺类化合物及其在医药上的应用
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Also Published As

Publication number Publication date
CN114728962A (zh) 2022-07-08
EP4031547A1 (en) 2022-07-27
EP4031547B1 (en) 2024-07-17
JP2025179190A (ja) 2025-12-09
ES2987744T3 (es) 2024-11-18
US11787796B2 (en) 2023-10-17
DK4031547T3 (da) 2024-09-09
US20230391773A1 (en) 2023-12-07
US20210078999A1 (en) 2021-03-18
US12221441B2 (en) 2025-02-11
JP7777519B2 (ja) 2025-11-28
JP2022548696A (ja) 2022-11-21
CN114728962B (zh) 2025-09-19
EP4477220A3 (en) 2025-02-26
PT4031547T (pt) 2024-08-27
FI4031547T3 (fi) 2024-09-16
WO2021055621A1 (en) 2021-03-25
EP4477220A2 (en) 2024-12-18

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