DK3565844T5 - Fremgangsmåder til behandling af cancer med anti-PD-1-antistoffer - Google Patents

Fremgangsmåder til behandling af cancer med anti-PD-1-antistoffer Download PDF

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Publication number
DK3565844T5
DK3565844T5 DK18704101.7T DK18704101T DK3565844T5 DK 3565844 T5 DK3565844 T5 DK 3565844T5 DK 18704101 T DK18704101 T DK 18704101T DK 3565844 T5 DK3565844 T5 DK 3565844T5
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Prior art keywords
antibodies
methods
treating cancer
cancer
treating
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DK18704101.7T
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Danish (da)
English (en)
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DK3565844T3 (da
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David Jenkins
Ellie Im
Allene Diaz
Sharon Lu
Haley A Laken
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Tesaro Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK18704101.7T 2017-01-09 2018-01-09 Fremgangsmåder til behandling af cancer med anti-PD-1-antistoffer DK3565844T5 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762444336P 2017-01-09 2017-01-09
US201762477423P 2017-03-27 2017-03-27
US201762491220P 2017-04-27 2017-04-27
US201762556386P 2017-09-09 2017-09-09
PCT/US2018/013029 WO2018129559A1 (en) 2017-01-09 2018-01-09 Methods of treating cancer with anti-pd-1 antibodies

Publications (2)

Publication Number Publication Date
DK3565844T3 DK3565844T3 (da) 2023-05-01
DK3565844T5 true DK3565844T5 (da) 2024-09-02

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DK18704101.7T DK3565844T5 (da) 2017-01-09 2018-01-09 Fremgangsmåder til behandling af cancer med anti-PD-1-antistoffer

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US (3) US11407830B2 (enExample)
EP (2) EP3565844B8 (enExample)
JP (2) JP7110206B6 (enExample)
KR (1) KR102606252B1 (enExample)
CN (1) CN110382545A (enExample)
AU (2) AU2018206481B2 (enExample)
BR (1) BR112019014187A2 (enExample)
CA (1) CA3049440A1 (enExample)
DK (1) DK3565844T5 (enExample)
ES (1) ES2945745T3 (enExample)
FI (1) FI3565844T3 (enExample)
HU (1) HUE061842T2 (enExample)
IL (1) IL267804B2 (enExample)
MA (1) MA47208A (enExample)
MX (1) MX2019008207A (enExample)
PL (1) PL3565844T3 (enExample)
PT (1) PT3565844T (enExample)
SG (2) SG10201913075RA (enExample)
TW (1) TWI767976B (enExample)
WO (1) WO2018129559A1 (enExample)
ZA (1) ZA201904316B (enExample)

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US20260193352A1 (en) 2026-07-09
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US20200239574A1 (en) 2020-07-30
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