DK355485A - Dinatrium-3-amino-l-hydroxy-propan-1,1-diphosphonat samt fremgangsmaade til fremstilling deraf - Google Patents

Dinatrium-3-amino-l-hydroxy-propan-1,1-diphosphonat samt fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK355485A
DK355485A DK355485A DK355485A DK355485A DK 355485 A DK355485 A DK 355485A DK 355485 A DK355485 A DK 355485A DK 355485 A DK355485 A DK 355485A DK 355485 A DK355485 A DK 355485A
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DK
Denmark
Prior art keywords
dinate
diphosphonate
propan
hydroxy
procedures
Prior art date
Application number
DK355485A
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English (en)
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DK355485D0 (da
DK167282B1 (da
Inventor
Peter Heinrich Stahl
Beat Schmitz
Original Assignee
Ciba Geigy Ag
Henkel Kgaa
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Application filed by Ciba Geigy Ag, Henkel Kgaa filed Critical Ciba Geigy Ag
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Publication of DK355485A publication Critical patent/DK355485A/da
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/16Esters of thiophosphoric acids or thiophosphorous acids
    • C07F9/165Esters of thiophosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3839Polyphosphonic acids
    • C07F9/3873Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK355485A 1984-08-06 1985-08-05 Krystallinsk, krystalvandholdigt dinatrium-3-amino-1-hydroxy-propan-1,1-diphosphonat paa ikke-hygroskopisk form, fremgangsmaader til fremstilling deraf, anvendelse deraf til fremstilling af farmaceutiske praeparater samt farmaceutiske praeparater med indhold deraf DK167282B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH376884 1984-08-06
CH376884 1984-08-06

Publications (3)

Publication Number Publication Date
DK355485D0 DK355485D0 (da) 1985-08-05
DK355485A true DK355485A (da) 1986-02-07
DK167282B1 DK167282B1 (da) 1993-10-04

Family

ID=4263070

Family Applications (1)

Application Number Title Priority Date Filing Date
DK355485A DK167282B1 (da) 1984-08-06 1985-08-05 Krystallinsk, krystalvandholdigt dinatrium-3-amino-1-hydroxy-propan-1,1-diphosphonat paa ikke-hygroskopisk form, fremgangsmaader til fremstilling deraf, anvendelse deraf til fremstilling af farmaceutiske praeparater samt farmaceutiske praeparater med indhold deraf

Country Status (26)

Country Link
US (2) US4639338A (da)
EP (1) EP0177443B1 (da)
JP (1) JPS6143196A (da)
KR (1) KR940000817B1 (da)
AR (4) AR240832A1 (da)
AT (1) ATE47396T1 (da)
AU (1) AU591066B2 (da)
CA (1) CA1255694A (da)
CY (1) CY1570A (da)
DD (1) DD239597A5 (da)
DE (1) DE3573783D1 (da)
DK (1) DK167282B1 (da)
DO (1) DOP1990004769A (da)
ES (2) ES8701188A1 (da)
FI (1) FI79712C (da)
GR (1) GR851910B (da)
HK (1) HK42591A (da)
HU (1) HU193124B (da)
IE (1) IE58077B1 (da)
IL (1) IL75990A (da)
MX (1) MX9203373A (da)
NO (1) NO165401C (da)
PH (1) PH24854A (da)
PT (1) PT80916B (da)
SG (1) SG91390G (da)
ZA (1) ZA855892B (da)

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EP0998932A1 (de) 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
US6160165A (en) * 1998-12-10 2000-12-12 Aesgen, Inc. Method for preparation of disodium pamidronate
DE69907258T2 (de) * 1998-12-10 2003-11-06 Aesgen Inc Verfahren zur herstellung von dinatriumpamidronat
US6794536B1 (en) * 1998-12-10 2004-09-21 Aesqen, Inc. Method for preparation of disodium pamidronate
US6143919A (en) * 1999-05-18 2000-11-07 3M Innovative Properties Company Polymerizable acidic compounds and methods of preparation
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Also Published As

Publication number Publication date
ES545899A0 (es) 1986-11-16
SG91390G (en) 1991-01-18
KR940000817B1 (ko) 1994-02-02
ES8706707A1 (es) 1987-07-01
DE3573783D1 (en) 1989-11-23
PH24854A (en) 1990-12-26
ATE47396T1 (de) 1989-11-15
NO165401C (no) 1991-02-06
DK355485D0 (da) 1985-08-05
JPS6143196A (ja) 1986-03-01
HUT38361A (en) 1986-05-28
JPH058717B2 (da) 1993-02-02
ES8701188A1 (es) 1986-11-16
ES555602A0 (es) 1987-07-01
AU4577785A (en) 1986-02-13
EP0177443A1 (de) 1986-04-09
FI852986L (fi) 1986-02-07
GR851910B (da) 1985-12-03
PT80916B (pt) 1987-12-30
AR240832A2 (es) 1991-02-28
US4711880A (en) 1987-12-08
PT80916A (en) 1985-09-01
AR244697A1 (es) 1993-11-30
US4639338A (en) 1987-01-27
NO165401B (no) 1990-10-29
CA1255694A (en) 1989-06-13
DK167282B1 (da) 1993-10-04
AR240832A1 (es) 1991-02-28
IE58077B1 (en) 1993-06-30
DD239597A5 (de) 1986-10-01
MX9203373A (es) 1992-09-01
IL75990A (en) 1989-07-31
FI79712B (fi) 1989-10-31
CY1570A (en) 1991-12-20
AU591066B2 (en) 1989-11-30
EP0177443B1 (de) 1989-10-18
ZA855892B (en) 1986-03-26
FI852986A0 (fi) 1985-08-02
DOP1990004769A (es) 1999-08-19
HK42591A (en) 1991-06-07
KR860001821A (ko) 1986-03-22
AR244696A1 (es) 1993-11-30
HU193124B (en) 1987-08-28
NO853087L (no) 1986-02-07
AR244698A1 (es) 1993-11-30
IE851931L (en) 1986-02-06
FI79712C (fi) 1990-02-12

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