DK3419991T3 - Modificerede ribosomale genpromotorer til proteinproduktion i mikroorganismer - Google Patents
Modificerede ribosomale genpromotorer til proteinproduktion i mikroorganismer Download PDFInfo
- Publication number
- DK3419991T3 DK3419991T3 DK17713100.0T DK17713100T DK3419991T3 DK 3419991 T3 DK3419991 T3 DK 3419991T3 DK 17713100 T DK17713100 T DK 17713100T DK 3419991 T3 DK3419991 T3 DK 3419991T3
- Authority
- DK
- Denmark
- Prior art keywords
- microorganisms
- protein production
- gene promoters
- ribosomal gene
- modified ribosomal
- Prior art date
Links
- 108020001027 Ribosomal DNA Proteins 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 230000014616 translation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01001—Alpha-amylase (3.2.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662304061P | 2016-03-04 | 2016-03-04 | |
| PCT/US2017/020913 WO2017152169A1 (en) | 2016-03-04 | 2017-03-06 | Engineered ribosomal promoters for protein production in microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3419991T3 true DK3419991T3 (da) | 2023-01-16 |
Family
ID=58402134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17713100.0T DK3419991T3 (da) | 2016-03-04 | 2017-03-06 | Modificerede ribosomale genpromotorer til proteinproduktion i mikroorganismer |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11447782B2 (enExample) |
| EP (2) | EP3419991B1 (enExample) |
| JP (2) | JP7103948B2 (enExample) |
| KR (1) | KR20180117166A (enExample) |
| CN (1) | CN109071615A (enExample) |
| DK (1) | DK3419991T3 (enExample) |
| FI (1) | FI3419991T3 (enExample) |
| WO (1) | WO2017152169A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200047668A (ko) * | 2017-09-13 | 2020-05-07 | 다니스코 유에스 인크. | 바실러스에서 증가된 단백질 생산을 위한 변형된 5'-비번역 영역(utr) 서열 |
| CN108441489B (zh) * | 2018-04-09 | 2023-04-14 | 潍坊康地恩生物科技有限公司 | 一种蛋白生产方法及高产碱性蛋白酶的枯草芽孢杆菌 |
| US20240279627A1 (en) | 2018-08-30 | 2024-08-22 | Danisco Us Inc | Compositions comprising a lipolytic enzyme variant and methods of use thereof |
| KR20210096629A (ko) * | 2018-11-28 | 2021-08-05 | 다니스코 유에스 인크. | 바실러스 세포에서의 향상된 단백질 생산을 위한 신규 프로모터 서열 및 이의 방법 |
| WO2021030267A1 (en) | 2019-08-14 | 2021-02-18 | Danisco Us Inc | Compositions and methods for increased protein production in bacillus licheniformis |
| US20230049452A1 (en) | 2020-01-13 | 2023-02-16 | Danisco Us Inc | Compositions comprising a lipolytic enzyme variant and methods of use thereof |
| AU2023272468A1 (en) | 2022-05-14 | 2024-11-14 | Novonesis Plant Biosolutions A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
| CN120129752A (zh) | 2022-09-02 | 2025-06-10 | 丹尼斯科美国公司 | 增强革兰氏阳性细胞中的蛋白质生产的新型启动子和5′-非翻译区突变 |
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-
2017
- 2017-03-06 EP EP17713100.0A patent/EP3419991B1/en active Active
- 2017-03-06 US US16/081,082 patent/US11447782B2/en active Active
- 2017-03-06 CN CN201780025872.5A patent/CN109071615A/zh active Pending
- 2017-03-06 JP JP2018546634A patent/JP7103948B2/ja active Active
- 2017-03-06 EP EP22174866.8A patent/EP4095152A3/en not_active Withdrawn
- 2017-03-06 WO PCT/US2017/020913 patent/WO2017152169A1/en not_active Ceased
- 2017-03-06 KR KR1020187027921A patent/KR20180117166A/ko not_active Withdrawn
- 2017-03-06 DK DK17713100.0T patent/DK3419991T3/da active
- 2017-03-06 FI FIEP17713100.0T patent/FI3419991T3/fi active
-
2022
- 2022-05-17 JP JP2022081023A patent/JP2022116087A/ja active Pending
- 2022-08-08 US US17/818,258 patent/US12077762B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20180117166A (ko) | 2018-10-26 |
| CN109071615A (zh) | 2018-12-21 |
| EP3419991A1 (en) | 2019-01-02 |
| JP2022116087A (ja) | 2022-08-09 |
| JP2019511218A (ja) | 2019-04-25 |
| US11447782B2 (en) | 2022-09-20 |
| FI3419991T3 (fi) | 2023-01-31 |
| WO2017152169A1 (en) | 2017-09-08 |
| EP4095152A3 (en) | 2022-12-28 |
| EP3419991B1 (en) | 2022-10-26 |
| US12077762B1 (en) | 2024-09-03 |
| US20190085341A1 (en) | 2019-03-21 |
| EP4095152A2 (en) | 2022-11-30 |
| JP7103948B2 (ja) | 2022-07-20 |
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